software . 2021

The landscape of circulating platelet aggregates in COVID-19

Zhou, Yuqi; Nishikawa, Masako; Kanno, Hiroshi; Xiao, Ting-Hui; Suzuki, Takuma; Ibayashi, Yuma; Harmon, Jeffrey; Takizawa, Shigekazu; Hiramatsu, Kotaro; Nitta, Nao; ...
Open Source
  • Published: 19 Aug 2021
  • Publisher: Zenodo
Abstract
A characteristic clinical feature of COVID-19 is the frequent occurrence of thrombotic events. Furthermore, many cases of multiorgan failure have been found to be thrombotic in nature. Since the outbreak of COVID-19, D-dimer testing has been used extensively to evaluate COVID-19-associated thrombosis, but does not provide a complete view of the disease because it probes blood coagulation, but not platelet activity. Due to this limitation, D-dimer testing fails to account for thrombotic events which occur despite low D-dimer levels, such as sudden stroke in young patients and autopsy-identified widespread microthrombi in multiple organs. Here we demonstrate large...
Communities
COVID-19
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Zenodo
Software . 2021
Provider: Datacite
Zenodo
Software . 2021
Provider: Datacite
Zenodo
Software . 2021
Provider: Datacite
Zenodo
Software . 2021
Provider: Datacite
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