publication . Article . 2004

Viral shedding patterns of coronavirus in patients with probable severe acute respiratory syndrome

Peter K.C. Cheng; Derek A. Wong; Louis K.L. Tong; Sin-Ming Ip; Angus C T Lo; C.S. Lau; Eugene Y.H. Yeung; Wilina Lim;
Open Access English
  • Published: 26 May 2004 Journal: Lancet (London, England), volume 363, issue 9,422, pages 1,699-1,700 (issn: 0140-6736, eissn: 1474-547X, Copyright policy)
  • Publisher: Elsevier Ltd.
Abstract
Summary Severe acute respiratory syndrome (SARS) is thought to be caused by a novel coronavirus, SARS-associated coronavirus. We studied viral shedding of SARS coronavirus to improve diagnosis and infection control. Reverse-transcriptase PCR was done on 2134 specimens of different types. 355 (45%) specimens of nasopharyngeal aspirates and 150 (28%) of faeces were positive for SARS coronavirus RNA. Positive rates peaked at 6–11 days after onset of illness for nasopharyngeal aspirates (87 of 149 [58%], to 37 of 62 [60%]), and 9–14 days for faeces (15 of 22 [68%], to 26 of 37 [70%]). Overall, peak viral loads were reached at 12–14 days of illness when patients were...
Subjects
Medical Subject Headings: viruses
free text keywords: Article, Nidovirales, biology.organism_classification, biology, Respiratory disease, medicine.disease, medicine, Viral shedding, Coronaviridae, Virology, Immunology, Viral disease, Viral load, Coronavirus, medicine.disease_cause, Virus, business.industry, business
Communities
COVID-19

Severe acute respiratory syndrome (SARS): multi-country outbreak—update 34.

Peiris, JSM, Lai, ST, Poon, LL. Coronavirus as a possible cause of severe acute respiratory syndrome. Lancet. 2003; 361: 1319-1325 [OpenAIRE] [PubMed]

Peiris, JSM, Chu, CM, Cheng, VCC. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. Lancet. 2003; 361: 1767-1772 [OpenAIRE] [PubMed]

Case definitions for surveillance of severe acute respiratory syndrome (SARS).

Tsang, OT, Chau, TN, Choi, KW. Coronavirus-positive nasopharyngeal aspirate as predictor for severe acute respiratory syndrome mortality. Emerg Infect Dis. 2003; 9: 1381-1387 [OpenAIRE] [PubMed]

Any information missing or wrong?Report an Issue