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Actas Dermo-Sifiliográficas (English Edition)
Article . 2021 . Peer-reviewed
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SARS-CoV-2 Vaccines and the Skin

Authors: Galván Casas, Cristina; Català, A.; Muñoz Santos, Carlos;

SARS-CoV-2 Vaccines and the Skin

Abstract

Vaccines against the severe acute respiratory coronavirus 2, which are the first to be used in humans against any coronavirus, were developed and produced in record time. Dermatologic adverse effects appeared during clinical trials and have also been described in the population since approval. Just as descriptions and categorization of skin manifestations of the coronavirus disease 2019 proved important for understanding the disease itself, characterizing the effects of vaccines may also further that goal. This paper reviews the properties of the different types of vaccines currently available and under development and describes how they interact with the immune system and the clinical signs they may cause. We focus on dermatologic adverse effects reported to date and recommendations for managing them.Las vacunas contra el SARS-CoV-2 son las primeras vacunas que han sido usadas en humanos contra coronavirus y su desarrollo se ha producido en un tiempo récord. En los análisis de seguridad de los ensayos clínicos previos a su aprobación y en la fase postautorización en la población, se han descrito efectos secundarios dermatológicos. La descripción y categorización de las manifestaciones cutáneas de la COVID-19 fueron importantes para el conocimiento de la enfermedad y de la misma forma pueden serlo las generadas por las vacunas. En este artículo hacemos un repaso a las características de los diferentes tipos de vacunas disponibles y en desarrollo, su modo de interacción con el sistema inmune, las consecuentes manifestaciones clínicas que pueden generar, con especial interés en los efectos secundarios dermatológicos hasta el momento descritos, y las actitudes terapéuticas recomendadas ante cada una de estas reacciones.

Subjects by Vocabulary

Microsoft Academic Graph classification: medicine.medical_specialty Coronavirus disease 2019 (COVID-19) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Population Disease medicine.disease_cause Immune system medicine Adverse effect Intensive care medicine education Coronavirus education.field_of_study business.industry Clinical trial business

Keywords

Vacunas, Vacunas contra SARS-CoV-2, Histology, Novelties in Dermatology, Dermatology, Vacunes, COVID-19 (Malaltia), :afecciones patológicas, signos y síntomas::signos y síntomas::manifestaciones cutáneas [ENFERMEDADES], Reacciones cutáneas, Pathology and Forensic Medicine, :virosis::infecciones por virus ARN::infecciones por Nidovirales::infecciones por Coronaviridae::infecciones por Coronavirus [ENFERMEDADES], :mezclas complejas::productos biológicos::vacunas [COMPUESTOS QUÍMICOS Y DROGAS], :Complex Mixtures::Biological Products::Vaccines [CHEMICALS AND DRUGS], :Pathological Conditions, Signs and Symptoms::Signs and Symptoms::Skin Manifestations [DISEASES], COVID-19, :Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections [DISEASES], Skin reactions, SARS-CoV-2 vaccines, Pell - Malalties

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  • citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    1
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average
gold
Related to Research communities
Corona Virus Disease