publication . Article . 2021

D-Dimers Level as a Possible Marker of Extravascular Fibrinolysis in COVID-19 Patients

Antonin Trimaille; Jecko Thachil; Benjamin Marchandot; Anaïs Curtiaud; Ian Leonard-Lorant; Adrien Carmona; Kensuke Matsushita; Chisato Sato; Laurent Sattler; Lelia Grunebaum; ...
Open Access English
  • Published: 01 Dec 2021 Journal: Journal of Clinical Medicine, volume 10, issue 1 (eissn: 2077-0383, Copyright policy)
  • Publisher: MDPI
Abstract
Background and Objective: Host defence mechanisms to counter virus infection include the activation of the broncho-alveolar haemostasis. Fibrin degradation products secondary to extravascular fibrin breakdown could contribute to the marked increase in D-Dimers during COVID-19. We sought to examine the prognostic value on lung injury of D-Dimers in non-critically ill COVID-19 patients without thrombotic events. Methods: This study retrospectively analysed hospitalized COVID-19 patients classified according to a D-Dimers threshold following the COVID-19 associated haemostatic abnormalities (CAHA) classification at baseline and at peak (Stage 1: D-Dimers less than ...
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Subjects
free text keywords: Article, coronavirus, fibrinolysis, lung injury, respiratory distress syndrome, thrombosis, lcsh:Medicine, lcsh:R
Communities
COVID-19
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