publication . Article . 2020

Vaccines and Therapies in Development for SARS-CoV-2 Infections

David Wu; Raghuram Koganti; Upendra P Lambe; Tejabhiram Yadavalli; Shyam Sundar Nandi; Deepak Shukla;
Open Access English
  • Published: 01 Jun 2020 Journal: Journal of Clinical Medicine, volume 9, issue 1,885 (issn: 2077-0383, Copyright policy)
  • Publisher: MDPI AG
Abstract
The current COVID-19 pandemic is caused by the novel coronavirus SARS-CoV-2. The virus causes severe respiratory symptoms which manifest disproportionately in the elderly. Currently, there are over 6.5 million cases and 380,000 deaths reported. Given the current severity of the outbreak, there is a great need for antiviral therapies and vaccines to treat and prevent COVID-19. In this review, we provide an overview of SARS-CoV-2 and discuss the emerging therapies and vaccines that show promise in combating COVID-19. We also highlight potential viral targets that could be exploited by researchers and drug manufacturers.
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Medical Subject Headings: viruses
free text keywords: SARS-CoV-2, therapies, vaccines, COVID-19, coronavirus, Review, General Medicine, lcsh:Medicine, lcsh:R, Outbreak, Medicine, business.industry, business, Coronavirus, medicine.disease_cause, Coronavirus disease 2019 (COVID-19), 2019-20 coronavirus outbreak, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Virus, Pandemic, Virology
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