publication . Article . 2017

Diagnostic Accuracy of FebriDx: A Rapid Test to Detect Immune Responses to Viral and Bacterial Upper Respiratory Infections

Wesley H. Self; Jeffrey Rosen; Stephan C Sharp; Michael R. Filbin; Peter C. Hou; Amisha Parekh; Michael C. Kurz; Nathan I. Shapiro;
Open Access
  • Published: 07 Oct 2017
  • Publisher: MDPI AG
C-reactive protein (CRP) and myxovirus resistance protein A (MxA) are associated with bacterial and viral infections, respectively. We conducted a prospective, multicenter, cross-sectional study of adults and children with febrile upper respiratory tract infections (URIs) to evaluate the diagnostic accuracy of a rapid CRP/MxA immunoassay to identify clinically significant bacterial infection with host response and acute pathogenic viral infection. The reference standard for classifying URI etiology was an algorithm that included throat bacterial culture, upper respiratory PCR for viral and atypical pathogens, procalcitonin, white blood cell count, and bandemia. ...
Persistent Identifiers
free text keywords: Article, respiratory infection, antibiotic stewardship, MxA, CRP, immunoassay, FebriDx, Respiratory infection, Medicine, business.industry, business, Internal medicine, medicine.medical_specialty, Etiology, Respiratory tract infections, Procalcitonin, White blood cell, medicine.anatomical_structure, Microbiological culture, Bandemia, Immunology, Immune system, Gastroenterology, lcsh:Medicine, lcsh:R
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