publication . Article . 2015

Treatment of Severe Acute Respiratory Syndrome With Glucosteroids

Rongchang Chen; Xiao Ping Tang; Shou Yong Tan; Bi Ling Liang; Zhuo Yue Wan; Ji Qian Fang; Nanshan Zhong;
Open Access English
  • Published: 01 Dec 2015 Journal: Chest, volume 129, issue 6, pages 1,441-1,452 (issn: 0012-3692, eissn: 1931-3543, Copyright policy)
  • Publisher: The American College of Chest Physicians. Published by Elsevier Inc.
Abstract
Study objective To investigate the efficacy and safety profiles of corticosteroid therapy in severe acute respiratory syndrome (SARS) patients. Design Four hundred one of 1,278 SARS cases treated in Guangzhou China between December 2002 and June 2003 fulfilled the diagnostic criteria issued by the World Health Organization for confirmed identification of SARS. Among them, the diagnosis of critical SARS was defined by criteria of SARS guidelines incorporated with a low oxygenation index (OI) [< 300 mm Hg]. Data of these patients retrieved from a database were retrospectively analyzed by logistic regression and Cox regression for the effect of corticosteroid thera...
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free text keywords: Article, complication, corticosteroid, mortality, SARS, ALI, acute lung injury, AVN, avascular osteonecrosis, CI, confidence interval, IL, interleukin, IP-10, interferon-inducible protein 10, OI, oxygenation index, OR, odds ratio, PCR, polymerase chain reaction, SARS, severe acute respiratory syndrome, SARS-CoV, severe acute respiratory syndrome coronavirus, Critical Care and Intensive Care Medicine, Pulmonary and Respiratory Medicine, Cardiology and Cardiovascular Medicine, Survival rate, Respiratory disease, medicine.disease, medicine, Mortality rate, Odds ratio, Univariate analysis, Surgery, medicine.medical_specialty, Complication, business.industry, business, Retrospective cohort study, Internal medicine, Epidemiology
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40 references, page 1 of 3

Drosten, C, Gunther, S, Preiser, W. Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N Engl J Med. 2003; 348: 1967-1976 [OpenAIRE] [PubMed]

Hui, DS, Sung, JJ. Treatment of severe acute respiratory syndrome. Chest. 2004; 126: 670-674 [OpenAIRE] [PubMed]

Zhao, Z, Zhang, F, Xu, M. Description and clinical treatment of an early outbreak of severe acute respiratory syndrome (SARS) in Guangzhou, PR China. J Med Microbiol. 2003; 52(Pt 8): 715-720 [PubMed]

So, LK, Lau, AC, Yam, LY. Development of a standard treatment protocol for severe acute respiratory syndrome. Lancet. 2003; 361: 1615-1617 [OpenAIRE] [PubMed]

Ho, JC, Ooi, GC, Mok, TY. High dose pulse versus non-pulse corticosteroid regimens in severe acute respiratory syndrome. Am J Respir Crit Care Med. 2003; 168: 1449-1456 [PubMed]

Meng, QH, Dong, PL, Guo, YB. Use of glucocorticoid in treatment of severe acute respiratory syndrome cases. Zhonghua Yu Fang Yi Xue Za Zhi. 2003; 37: 233-235 [PubMed]

Xiao, JZ, Ma, L, Gao, J. Glucocorticoid-induced diabetes in severe acute respiratory syndrome: the impact of high dosage and duration of methylprednisolone therapy. Chin J Intern Med. 2004; 43: 179-182

Sung, JJ, Wu, A, Joynt, GM. Severe acute respiratory syndrome: report of treatment and outcome after a major outbreak. Thorax. 2004; 59: 414-420 [OpenAIRE] [PubMed]

Zhong, NS. Management and prevention of SARS in China. Phil Trans R Soc Lond B Biol Sci. 2004; 359: 1115-1116 [OpenAIRE] [PubMed]

Cheng, VC, Tang, BS, Wu, AK. Medical treatment of viral pneumonia including SARS in immunocompetent adult. J Infect. 2004; 49: 262-273 [OpenAIRE] [PubMed]

Tsang, K, Zhong, NS. SARS: pharmacotherapy. Respirology. 2003; 8: 25-30

Mishra, S, Lee, WM, Bressler, B. High dose intravenous methylprednisolone in the treatment of severe acute respiratory syndrome. Can Respir J. 2004; 11: 311-312 [PubMed]

Lee, N, Hui, D, Wu, A. A major outbreak of severe acute respiratory syndrome in Hong Kong. N Engl J Med. 2003; 348: 1986-1994 [PubMed]

40 references, page 1 of 3
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