publication . Article . 2015

Treatment of Severe Acute Respiratory Syndrome With Glucosteroids

Rongchang Chen; Xiao Ping Tang; Shou Yong Tan; Bi Ling Liang; Zhuo Yue Wan; Ji Qian Fang; Nanshan Zhong;
Open Access English
  • Published: 01 Dec 2015 Journal: Chest, volume 129, issue 6, pages 1,441-1,452 (issn: 0012-3692, eissn: 1931-3543, Copyright policy)
  • Publisher: The American College of Chest Physicians. Published by Elsevier Inc.
Study objective To investigate the efficacy and safety profiles of corticosteroid therapy in severe acute respiratory syndrome (SARS) patients. Design Four hundred one of 1,278 SARS cases treated in Guangzhou China between December 2002 and June 2003 fulfilled the diagnostic criteria issued by the World Health Organization for confirmed identification of SARS. Among them, the diagnosis of critical SARS was defined by criteria of SARS guidelines incorporated with a low oxygenation index (OI) [< 300 mm Hg]. Data of these patients retrieved from a database were retrospectively analyzed by logistic regression and Cox regression for the effect of corticosteroid thera...
Persistent Identifiers
free text keywords: Article, complication, corticosteroid, mortality, SARS, ALI, acute lung injury, AVN, avascular osteonecrosis, CI, confidence interval, IL, interleukin, IP-10, interferon-inducible protein 10, OI, oxygenation index, OR, odds ratio, PCR, polymerase chain reaction, SARS, severe acute respiratory syndrome, SARS-CoV, severe acute respiratory syndrome coronavirus, Critical Care and Intensive Care Medicine, Pulmonary and Respiratory Medicine, Cardiology and Cardiovascular Medicine, Survival rate, Respiratory disease, medicine.disease, medicine, Mortality rate, Odds ratio, Univariate analysis, Surgery, medicine.medical_specialty, Complication, business.industry, business, Retrospective cohort study, Internal medicine, Epidemiology
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