publication . Article . 2017

Ebola Virus Neutralizing Antibodies Detectable in Survivors of theYambuku, Zaire Outbreak 40 Years after Infection

Anne W. Rimoin; Kai Lu; Matthew S. Bramble; Imke Steffen; Reena H. Doshi; Nicole A. Hoff; Patrick Mukadi; Bradly P. Nicholson; Vivian H. Alfonso; Gerrard Olinger; ...
Open Access
  • Published: 14 Dec 2017 Journal: The Journal of Infectious Diseases, volume 217, issue 2, pages 223-231 (issn: 0022-1899, eissn: 1537-6613, Copyright policy)
  • Publisher: Oxford University Press (OUP)
Duration of immunity against Ebola virus among survivors remains unclear. We assessed serological immune profiles and retention of Ebola virus neutralizing antibodies in 14 survivors of the 1976 Yambuku outbreak 40 years postinfection, providing the longest documentation of such measures reported.
Persistent Identifiers
Medical Subject Headings: virusesvirus diseaseshumanitiesbiochemical phenomena, metabolism, and nutrition
free text keywords: Infectious Diseases, Immunology and Allergy, Humans, Hemorrhagic Fever, Ebola, Antibodies, Viral, Antigens, Enzyme-Linked Immunosorbent Assay, Neutralization Tests, Disease Outbreaks, Time Factors, Adolescent, Adult, Aged, 80 and over, Middle Aged, Survivors, Democratic Republic of the Congo, Female, Male, Ebolavirus, Young Adult, Neutralizing, Viral Plaque Assay, Surveys and Questionnaires, Ebola virus, filovirus, serological response, virus neutralization, and over, Microbiology, Biological Sciences, Medical and Health Sciences, Major Articles and Brief Reports, Viruses, Ebola virus, Democratic Republic of the Congo, virus neutralization, serological response, filovirus, Outbreak, Serology, VP40, Virology, Ebola virus, medicine.disease_cause, medicine, Neutralization, Antibody, biology.protein, biology, Plaque reduction neutralization test, business.industry, business, Virus
Funded by
NIH| Serological prevalence of viral hemorrhagic fevers in Equatorial Africa
  • Funder: National Institutes of Health (NIH)
  • Project Code: 5R21AI107420-02
NIH| University of California Global Health Institute Program for Fellows and Scholars
  • Funder: National Institutes of Health (NIH)
  • Project Code: 5D43TW009343-07
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