publication . Article . 2021

Viral Load of Severe Acute Respiratory Syndrome Coronavirus 2 in Adults During the First and Second Wave of Coronavirus Disease 2019 Pandemic in Houston, Texas: The Potential of the Superspreader

Vasanthi Avadhanula; Erin G Nicholson; Laura Ferlic-Stark; Felipe-Andres Piedra; Brittani N Blunck; Sonia Fragoso; Nanette L Bond; Patricia L Santarcangelo; Xunyan Ye; Trevor J McBride; ...
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  • Published: 15 Feb 2021 Journal: The Journal of Infectious Diseases (issn: 0022-1899, eissn: 1537-6613, Copyright policy)
  • Publisher: Oxford University Press (OUP)
Abstract
<jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>During the coronavirus disease 2019 pandemic, a minority of index cases are associated with a majority of secondary cases suggesting that superspreaders could drive the pandemic. We identified a phenotype in individuals with extremely high viral load who could act as superspreaders.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Data were analyzed from individuals tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from 18 March through 15 August 2020. Outcomes were compared using contingency table and quantile regression to test the eq...
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free text keywords: Immunology and Allergy, Infectious Diseases
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