publication . Article . 2021

Long-Term Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infectiousness Among Three Immunocompromised Patients: From Prolonged Viral Shedding to SARS-CoV-2 Superinfection

Hassan Tarhini; Amélie Recoing; Antoine Bridier-Nahmias; Mayda Rahi; Céleste Lambert; Pascale Martres; Jean-Christophe Lucet; Christophe Rioux; Donia Bouzid; Samuel Lebourgeois; ...
Open Access
  • Published: 08 Feb 2021 Journal: The Journal of Infectious Diseases (issn: 0022-1899, eissn: 1537-6613, Copyright policy)
  • Publisher: Oxford University Press (OUP)
<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background</jats:title> <jats:p>Guidelines for stopping coronavirus disease 2019 patient isolation are mainly symptom-based, with isolation for 10 to 20 days depending on their condition.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods</jats:title> <jats:p>In this study, we describe 3 deeply immunocompromised patients, each with different clinical evolutions. We observed (1) the patients’ epidemiological, clinical, and serological data, (2) infectiousness using viral culture, and (3) viral mutations accumulated over time.</jats:p> </jats:sec> <jats:sec> <jats:title>Results</jats:title> <jats:p>Asymptom...
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free text keywords: Immunology and Allergy, Infectious Diseases, Serology, Viral shedding, Medicine, business.industry, business, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Asymptomatic, medicine.symptom, Carriage, Viral culture, Virology, Epidemiology, medicine.medical_specialty, Superinfection, medicine.disease_cause
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