publication . Article . 2021

Describing variability in pig genes involved in coronavirus infections for a One Health perspective in conservation of animal genetic resources

Samuele Bovo; Giuseppina Schiavo; Anisa Ribani; Valerio Joe Utzeri; Valeria Taurisano; Mohamad Ballan; María Muñoz; Estefania Alves; J. P. Araujo; Riccardo Bozzi; ...
Open Access English
  • Published: 09 Feb 2021
  • Publisher: Nature Research
Abstract
<jats:title>Abstract</jats:title><jats:p>Coronaviruses silently circulate in human and animal populations, causing mild to severe diseases. Therefore, livestock are important components of a “One Health” perspective aimed to control these viral infections. However, at present there is no example that considers pig genetic resources in this context. In this study, we investigated the variability of four genes (<jats:italic>ACE2</jats:italic>, <jats:italic>ANPEP</jats:italic> and <jats:italic>DPP4</jats:italic> encoding for host receptors of the viral spike proteins and <jats:italic>TMPRSS2</jats:italic> encoding for a host proteinase) in 23 European (19 autochtho...
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Subjects
free text keywords: 619, Angiotensin-Converting Enzyme 2, Animals, Breeding, CD13 Antigens, Coronavirus Infections, Dipeptidyl Peptidase 4, Gene Frequency, Genetics, Population, High-Throughput Nucleotide Sequencing, Humans, INDEL Mutation, One Health, Polymorphism, Single Nucleotide, Receptors, Virus, Serine Endopeptidases, Sus scrofa, Swine, Whole Genome Sequencing, Genetic Variation, pig ; local breed ; whole genome sequencing ; coronavirus, Angiotensin-Converting Enzyme 2; Animals; Breeding; CD13 Antigens; Coronavirus Infections; Dipeptidyl Peptidase 4; Gene Frequency; Genetics, Population; High-Throughput Nucleotide Sequencing; Humans; INDEL Mutation; One Health; Polymorphism, Single Nucleotide; Receptors, Virus; Serine Endopeptidases; Sus scrofa; Swine; Whole Genome Sequencing; Genetic Variation, Multidisciplinary, Article, Infectious diseases, Data mining, Next-generation sequencing, Agricultural genetics, Animal breeding, Genetic markers, Genomics, Population genetics, Genetic resources, Candidate gene, Genetics, Wild boar, biology.animal, biology, Population, education.field_of_study, education, One Health, Gene, Coronavirus Infections, Livestock, business.industry, business, lcsh:Medicine, lcsh:R, lcsh:Science, lcsh:Q
Funded by
EC| TREASURE
Project
TREASURE
DIVERSITY OF LOCAL PIG BREEDS AND PRODUCTION SYSTEMS FOR HIGH QUALITY TRADITIONAL PRODUCTS AND SUSTAINABLE PORK CHAINS
  • Funder: European Commission (EC)
  • Project Code: 634476
  • Funding stream: H2020 | RIA
Communities
COVID-19
Agricultural and Food SciencesAGINFRA+ Projects: DIVERSITY OF LOCAL PIG BREEDS AND PRODUCTION SYSTEMS FOR HIGH QUALITY TRADITIONAL PRODUCTS AND SUSTAINABLE PORK CHAINS
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