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LFIA YÖNTEMİ İLE COVID 19 TAŞIYICILIĞININ SAPTANMASI: BİR SEROPREVALANS ÇALIŞMASI

Authors: Akman, Nazife; Akidağı, Zeynep; Özmen, Pelin; Yalap, Rukiye;

LFIA YÖNTEMİ İLE COVID 19 TAŞIYICILIĞININ SAPTANMASI: BİR SEROPREVALANS ÇALIŞMASI

Abstract

ÖZET Koronavirüs hastalığı 2019 (COVID-19) hızlı yayılım gösteren bir pandemidir. Hastalığın yayılmasında virüse bağlı etmenlerin (viral yük, ACE bağlama proteini vs.) yanı sıra asemptomatik bireylerin de rolü azımsanmayacak miktardadır. COVID-19 pandemisinde, toplumda virüsün yayılmasına neden olan sessiz bulaştırıcıları saptamak için Kapadokya Üniversitesi sağlık programlarında öğrenim gören 18-40 yaş arasındaki 258 öğrencide SARS-CoV-2 seroprevalansı araştırıldı. Katılımcıların yaş ortalaması 21,5 (min = 18, max= 33) olup %69’u (n=38) kız öğrenciydi. Çalışmada bireylerin seroprevalans taramasında LFIA (Lateral Flow Immuno Assay) yöntemi kullanılarak SARS-COV-2 virüsüne karşı antikor yanıtları tarandı ve hastalık bulguları, PZR (polimeraz zincir reaksiyonu) testi ve şüpheli temas öyküsü yönünden değerlendirildi. Çalışmamızda SARS-CoV-2 seropozitifliği %21 (n=55) olarak saptanmış olup bu bireylerin %25’inin (n=14) son altı ay içinde PZR pozitiflikleri bulunmaktaydı. %56’sının (n=31) semptom göstermediği için test yaptırmadığını fakat SARS-COV-2 antikor pozitifliği saptandı. Bu oranlar, toplumdaki sessiz bulaştırıcıların yaygınlığını ortaya koymuştur. Bu çalışma seroepidemiyolojik veri eldesi açısından değerli olmakla birlikte koruyucu bağışıklık göstergesi olarak kabul edilmemelidir.

Country
Turkey
Related Organizations
Keywords

Sars-Cov-2, Seroprevalans, Covıd19, LFIA

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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