publication . Preprint . 2020

Evolution of outcomes for patients hospitalized during the first SARS-CoV-2 pandemic wave in France

Lefrancq, Noémie; Paireau, Juliette; Hozé, Nathanaël; Courtejoie, Noémie; Yazdanpanah, Yazdan; Bouadma, Lila; Boëlle, Pierre-Yves; Chereau, Fanny; Salje, Henrik; Cauchemez, Simon;
English
  • Published: 23 Sep 2020
  • Publisher: HAL CCSD
  • Country: France
Abstract
As SARS-CoV-2 continues to spread, a thorough characterization of healthcare needs and patient outcomes is essential to inform planning; however, these analyses are complicated by ongoing changes in patient profiles. Here we develop age and sex adjusted models to analyze detailed patient trajectories from 91,304 hospitalizations in France during the first 4 months of the epidemic. Only 25% of hospital deaths occurred in patients that were admitted into ICU. The probability of entering ICU fell by 50% and the probability of death by 52% over the study period. Had the age and sex profile not changed over time, these reductions would have been 59% and 56%, respectively. These findings suggest substantial improvements in patient outcomes since the start of the pandemic.
Subjects
free text keywords: SARS-CoV-2, COVID-19, epidemiology, hospital, ICU, outcome, delays, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
Communities
  • COVID-19
Funded by
ANR| INCEPTION
Project
INCEPTION
Institut Convergences pour l’étude de l’Emergence des Pathologies au Travers des Individus et des populatiONs
  • Funder: French National Research Agency (ANR) (ANR)
  • Project Code: ANR-16-CONV-0005
,
EC| VEO
Project
VEO
Versatile Emerging infectious disease Observatory
  • Funder: European Commission (EC)
  • Project Code: 874735
  • Funding stream: H2020 | RIA
,
EC| ARBODYNAMIC
Project
ARBODYNAMIC
Coupling dynamic population immunity profiles and host behaviours to arboviral spread
  • Funder: European Commission (EC)
  • Project Code: 804744
  • Funding stream: H2020 | ERC | ERC-STG
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