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Evolution of outcomes for patients hospitalized during the first SARS-CoV-2 pandemic wave in France

Authors: Lefrancq, Noémie; Paireau, Juliette; Hozé, Nathanaël; Courtejoie, Noémie; Yazdanpanah, Yazdan; Bouadma, Lila; Boëlle, Pierre-Yves; +3 Authors

Evolution of outcomes for patients hospitalized during the first SARS-CoV-2 pandemic wave in France

Abstract

As SARS-CoV-2 continues to spread, a thorough characterization of healthcare needs and patient outcomes is essential to inform planning; however, these analyses are complicated by ongoing changes in patient profiles. Here we develop age and sex adjusted models to analyze detailed patient trajectories from 91,304 hospitalizations in France during the first 4 months of the epidemic. Only 25% of hospital deaths occurred in patients that were admitted into ICU. The probability of entering ICU fell by 50% and the probability of death by 52% over the study period. Had the age and sex profile not changed over time, these reductions would have been 59% and 56%, respectively. These findings suggest substantial improvements in patient outcomes since the start of the pandemic.

Country
France
Keywords

SARS-CoV-2, delays, [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie, ICU, outcome, COVID-19, epidemiology, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, hospital

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    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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Corona Virus Disease