publication . Article . 2021

Prognostic Role of Neutrophil to Lymphocyte Ratio in COVID-19 Patients: Still Valid in Patients That Had Started Therapy?

Monica Gelzo; Monica Gelzo; Sara Cacciapuoti; Biagio Pinchera; Annunziata De Rosa; Gustavo Cernera; Gustavo Cernera; Filippo Scialò; Filippo Scialò; Mauro Mormile; ...
Open Access English
  • Published: 01 Jun 2021 Journal: Frontiers in Public Health, volume 9 (issn: 2296-2565, Copyright policy)
  • Publisher: Frontiers Media S.A.
COVID-19 may appear with a widely heterogeneous clinical expression. Thus, predictive markers of the outcome/progression are of paramount relevance. The neutrophil/lymphocyte ratio (NLR) has been suggested as a good predictive marker of disease severity and mortality. Accordingly, we found that NLR significantly increased in parallel with the WHO severity stage in COVID-19 patients during the Ist wave (March-May 2020; n = 49), due to the significant reduction of lymphocyte and the significant increase of neutrophil in severe COVID-19 patients. While, we did not observe significant differences of NLR between the WHO severity stage among COVID-19 patients of the I...
free text keywords: COVID-19, neutrophil to lymphocyte ratio, interleukin-6, myeloperoxidase, corticosteroid therapy, Public aspects of medicine, RA1-1270
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