project . 2020 - 2022 . On going

Fight-nCoV

FIGHTING-OFF CORONAVIRUS (SARS-CoV-2) WITH BROAD-SPECTRUM ANTIVIRALS: ESTABLISHING ANIMAL VIRAL CHALLENGE MODEL

Open Access mandate for Publications European Commission

Funder: European CommissionProject code: 101003555 Call for proposal: H2020-SC1-PHE-CORONAVIRUS-2020
Funded under: H2020 | RIA Overall Budget: 2,807,030 EURFunder Contribution: 2,807,030 EUR
Status: On going
Start Date
01 Apr 2020
End Date
31 Mar 2022
Detailed project information (CORDIS)

Open Access mandate
Research Data: No

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Description

Project coordinator: Professor Anna-Lena Spetz, MD, PhD, Stockholm University, Sweden Objectives of proposal: Our consortium “Fight-nCoV” will accelerate preclinical development of new broad-spectrum antivirals for inhalation, building on breath-taking ongoing research. We will determine and characterize the antiviral activity and safety of three viral entry inhibitors (oligonucleotide, Macro-I, tweezer) against SARS-CoV-2 in vitro and in vivo. To enable this, we will build capacity for evaluation of antiviral efficacy against SARS-CoV-2 in vitro using viral pseudotypes and wild-type SARS-CoV-2 as well as in vivo in non-human primates. Safety studies will be per...

Partners

ADLEGO BIOMEDICAL AB, University of Ulm, AU, University of Duisburg-Essen, CEA, Stockholm University

Summary

Description

Partners

ADLEGO BIOMEDICAL AB, University of Ulm, AU, University of Duisburg-Essen, CEA, Stockholm University

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