project . 2020 - 2022 . On going

Fight-nCoV

FIGHTING-OFF CORONAVIRUS (SARS-CoV-2) WITH BROAD-SPECTRUM ANTIVIRALS: ESTABLISHING ANIMAL VIRAL CHALLENGE MODEL
Open Access mandate for Publications European Commission
  • Funder: European CommissionProject code: 101003555 Call for proposal: H2020-SC1-PHE-CORONAVIRUS-2020
  • Funded under: H2020 | RIA Overall Budget: 2,807,030 EURFunder Contribution: 2,807,030 EUR
  • Status: On going
  • Start Date
    01 Apr 2020
    End Date
    31 Mar 2022
  • Detailed project information (CORDIS)
  • Open Access mandate
    Research Data: No
Description
Project coordinator: Professor Anna-Lena Spetz, MD, PhD, Stockholm University, Sweden Objectives of proposal: Our consortium “Fight-nCoV” will accelerate preclinical development of new broad-spectrum antivirals for inhalation, building on breath-taking ongoing research. We will determine and characterize the antiviral activity and safety of three viral entry inhibitors (oligonucleotide, Macro-I, tweezer) against SARS-CoV-2 in vitro and in vivo. To enable this, we will build capacity for evaluation of antiviral efficacy against SARS-CoV-2 in vitro using viral pseudotypes and wild-type SARS-CoV-2 as well as in vivo in non-human primates. Safety studies will be per...
Description
Project coordinator: Professor Anna-Lena Spetz, MD, PhD, Stockholm University, Sweden Objectives of proposal: Our consortium “Fight-nCoV” will accelerate preclinical development of new broad-spectrum antivirals for inhalation, building on breath-taking ongoing research. We will determine and characterize the antiviral activity and safety of three viral entry inhibitors (oligonucleotide, Macro-I, tweezer) against SARS-CoV-2 in vitro and in vivo. To enable this, we will build capacity for evaluation of antiviral efficacy against SARS-CoV-2 in vitro using viral pseudotypes and wild-type SARS-CoV-2 as well as in vivo in non-human primates. Safety studies will be per...
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