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173 Research products, page 1 of 18

  • COVID-19
  • French National Research Agency (ANR)
  • FR
  • IL
  • Hal-Diderot
  • Mémoires en Sciences de l'Information et de la Communication
  • Hyper Article en Ligne - Sciences de l'Homme et de la Société

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  • Open Access English
    Authors: 
    Peter Czuppon; Florence Débarre; Antonio Gonçalves; Olivier Tenaillon; Alan S. Perelson; Jeremie Guedj; François Blanquart;
    Publisher: HAL CCSD
    Country: France
    Project: ANR | TheraCoV (ANR-20-COVI-0018), ANR | TheoGeneDrive (ANR-19-CE45-0009), EC | PolyPath (844369)

    Abstract Repurposed drugs that are immediately available and have a good safety profile constitute a first line of defense against new viral infections. Despite a limited antiviral activity against SARS-CoV-2, several drugs serve as candidates for application, not only ...

  • Open Access English
    Authors: 
    Matthieu Van Tilbeurgh; Katia Lemdani; Anne Sophie Beignon; Catherine Chapon; Nicolas Tchitchek; Lina Cheraitia; Ernesto Marcos Lopez; Quentin Pascal; Roger Le Grand; Pauline Maisonnasse; +1 more
    Publisher: HAL CCSD
    Country: France
    Project: ANR | IDMIT (ANR-11-INBS-0008)

    International audience; Vaccines represent one of the major advances of modern medicine. Despite the many successes of vaccination, continuous efforts to design new vaccines are needed to fight “old” pandemics, such as tuberculosis and malaria, as well as emerging patho...

  • Open Access English
    Authors: 
    Trapman, Pieter; Ball, Frank; Dhersin, Jean-Stéphane; Tran, Viet Chi; Wallinga, Jacco; Britton, Tom;
    Countries: United Kingdom, France, United Kingdom
    Project: ANR | CEMPI (ANR-11-LABX-0007)

    When controlling an emerging outbreak of an infectious disease, it is essential to know the key epidemiological parameters, such as the basic reproduction number R 0 and the control effort required to prevent a large outbreak. These parameters are estimated from the ob...

  • Open Access English
    Authors: 
    Jacques Piazzola; William Bruch; Christelle Desnues; Philippe Parent; Christophe Yohia; Elisa Canepa;
    Publisher: HAL CCSD
    Country: France
    Project: ANR | MATRAC (ANR-18-ASTR-0002)

    International audience; Human behaviors probably represent the most important causes of the SARS-Cov-2 virus propagation. However, the role of virus transport by aerosols—and therefore the influence of atmospheric conditions (temperature, humidity, type and concentratio...

  • Open Access English
    Authors: 
    Nicolas eDegauque; Nicolas eDegauque; Nicolas eDegauque; Nicolas eDegauque; Sophie eBrouard; Sophie eBrouard; Sophie eBrouard; Sophie eBrouard; Sophie eBrouard; Sophie eBrouard; +4 more
    Publisher: Frontiers Media S.A.
    Country: France
    Project: ANR | IGO (ANR-11-LABX-0016), EC | VISICORT (602470)

    International audience; Being able to track donor reactive T cells during the course of organ transplantation is a key to improve the graft survival, to prevent graft dysfunction, and to adapt the immunosuppressive regimen. The attempts of transplant immunologists have ...

  • Open Access English
    Authors: 
    Mathieu Andraud; Maribel Casas; Nicole Pavio; Nicolas Rose;
    Publisher: Public Library of Science (PLoS)
    Country: France
    Project: ANR | HEVECODYN (ANR-10-CESA-0010)

    International audience; Passive immunity (PI), acquired through colostrum intake, is essential for piglet protection against pathogens. Maternally-derived antibodies (MDAs) can decrease the transmission of pathogens between individuals by reducing shedding from infected...

  • English
    Authors: 
    Berger, Loïc; Berger, Nicolas; Bosetti, Valentina; Gilboa, Itzhak; Hansen, Lars,; Jarvis, Christopher; Marinacci, Massimo; Smith, Richard,;
    Publisher: HAL CCSD
    Country: France
    Project: ANR | ECODEC (ANR-11-LABX-0047), ANR | INDUCED (ANR-17-CE03-0008), ANR | IPS (ANR-11-IDEX-0003), EC | INDIMACRO (670337), EC | RISICO (336703)

    Policymaking during a pandemic can be extremely challenging. As COVID-19 is a new disease and its global impacts are unprecedented, decisions need to be made in a highly uncertain, complex and rapidly changing environment. In such a context, in which human lives and the...

  • Open Access English
    Authors: 
    Aurélien Marc; Marion Kerioui; François Blanquart; Julie Bertrand; Oriol Mitjà; Marc Corbacho-Monné; Michael Marks; Jeremie Guedj;
    Publisher: HAL CCSD
    Countries: France, United Kingdom
    Project: ANR | TheraCoV (ANR-20-COVI-0018)

    The relationship between SARS-CoV-2 viral load and infectiousness is poorly known. Using data from a cohort of cases and high-risk contacts, we reconstructed viral load at the time of contact and inferred the probability of infection. The effect of viral load was larger...

  • Open Access English
    Authors: 
    Ludivine Grzelak; Sarah Temmam; Cyril Planchais; Caroline Demeret; Laura Tondeur; Christèle Huon; Florence Guivel-Benhassine; Isabelle Staropoli; Maxime Chazal; Jérémy Dufloo; +46 more
    Publisher: American Association for the Advancement of Science (AAAS)
    Country: France
    Project: ANR | CHIKV-Viro-Immuno (ANR-14-CE14-0015), ANR | TIMTAMDEN (ANR-14-CE14-0029), EC | RECoVER (101003589)

    It is of paramount importance to evaluate the prevalence of both asymptomatic and symptomatic cases of SARS-CoV-2 infection and their differing antibody response profiles. Here, we performed a pilot study of four serological assays to assess the amounts of anti–SARS-CoV...

  • Open Access English
    Authors: 
    Guillaume Castel; Mathilde Couteaudier; Frank Sauvage; Jean-Baptiste Pons; Séverine Murri; Angelina Plyusnina; Dominique Pontier; Jean-François Cosson; Alexander Plyusnin; Philippe Marianneau; +1 more
    Countries: France, Finland
    Project: EC | EDENEXT (261504), ANR | ECOFECT (ANR-11-LABX-0048), EC | ANTIGONE (278976), ANR | Avenir L.S.E. (ANR-11-IDEX-0007)

    Puumala virus (PUUV) is the agent of nephropathia epidemica (NE), a mild form of hemorrhagic fever with renal syndrome (HFRS) in Europe. NE incidence presents a high spatial variation throughout France, while the geographical distribution of the wild reservoir of PUUV, ...