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The following results are related to COVID-19. Are you interested to view more results? Visit OpenAIRE - Explore.
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14 research outcomes, page 1 of 2
  • publication . Article . 2021
    Open Access English
    Authors:
    Harry Sokol; Vanessa Contreras; Pauline Maisonnasse; Aurore Desmons; Benoit Delache; Valentin Sencio; Arnaud Machelart; Angela Brisebarre; Lydie Humbert; Lucie Deryuter; ...
    Publisher: HAL CCSD
    Project: ANR | IDMIT (ANR-11-INBS-0008), ANR | ACROBAT (ANR-17-CE15-0020)

    International audience; The current pandemic of coronavirus disease (COVID) 2019 constitutes a global public health issue. Regarding the emerging importance of the gut-lung axis in viral respiratory infections, analysis of the gut microbiota's composition and functional...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Stanislas Grassin-Delyle; Camille Roquencourt; Pierre Moine; Gabriel Saffroy; Stanislas Carn; Nicholas Heming; Jérôme Fleuriet; Hélène Salvator; Emmanuel Naline; Louis Jean Couderc; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | RECORDS (ANR-18-RHUS-0004), ANR | SoftwAiR (ANR-18-CE45-0017)

    Background: Early diagnosis of coronavirus disease 2019 (COVID-19) is of the utmost importance but remains challenging. The objective of the current study was to characterize exhaled breath from mechanically ventilated adults with COVID-19. Methods: In this prospective ...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Paul Bastard; Lindsey B. Rosen; Qian Zhang; Eleftherios Michailidis; Hans-Heinrich Hoffmann; Yu Zhang; Karim Dorgham; Quentin Philippot; Jérémie Rosain; Vivien Béziat; ...
    Publisher: HAL CCSD
    Project: ANR | IFN-COVID19 (ANR-20-COVI-0064), NIH | NHGRI Genome Sequencing P... (5U24HG008956-02), NIH | Developing, Demonstrating... (5UL1TR001866-03), NIH | Modulation of Human Dendr... (5U19AI111825-02), NIH | Inborn errors of immunity... (5R01AI088364-07), NIH | Type I interferon-stimula... (5R01AI091707-05), NIH | Yale Center for Mendelian... (5UM1HG006504-07)

    COVID Human Genetic Effort Laurent Abel1, Alessandro Aiuti2, Saleh Al Muhsen3, Fahd Al-Mulla4, Mark S. Anderson5, Andrés Augusto Arias6, Hagit Baris Feldman7, Dusan Bogunovic8, Alexandre Bolze9, Anastasiia Bondarenko10, Ahmed A. Bousfiha11, Petter Brodin12, Yenan Bryces...

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Marc-André Hograindleur; Gregory Effantin; Daphna Fenel; Caroline Mas; André Lieber; Guy Schoehn; Pascal Fender; Emilie Vassal-Stermann;
    Persistent Identifiers
    Publisher: MDPI
    Project: ANR | Ad-Cadh (ANR-18-CE11-0001), ANR | CBH-EUR-GS (ANR-17-EURE-0003)

    The study of viruses causing acute respiratory distress syndromes (ARDS) is more essential than ever at a time when a virus can create a global pandemic in a matter of weeks. Among human adenoviruses, adenovirus of serotype 7 (HAdV7) is one of the most virulent serotype...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Pauline Maisonnasse; Jeremie Guedj; Vanessa Contreras; Sylvie Behillil; Caroline Solas; Romain Marlin; Thibaut Naninck; Andrés Pizzorno; Julien Lemaitre; Antonio Gonçalves; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | TRANSVAC2 (730964), ANR | IDMIT (ANR-11-INBS-0008), EC | EVAg (653316), EC | Fight-nCoV (101003555)

    International audience; Coronavirus disease 2019 (COVID-19) has rapidly become a global pandemic and no antiviral drug or vaccine is yet available for the treatment of this disease1-3. Several clinical studies are ongoing to evaluate the efficacy of repurposed drugs tha...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Simon G. P. Funnell; W. E. Dowling; César Muñoz-Fontela; Pierre Stéphane Gsell; Donald E. Ingber; G. A. Hamilton; Leen Delang; Joana Rocha-Pereira; Suzanne J. F. Kaptein; K. H. Dallmeier; ...
    Persistent Identifiers
    Publisher: Nature Publishing Group UK
    Project: EC | EVAg (653316), EC | TRANSVAC2 (730964), ANR | IDMIT (ANR-11-INBS-0008), NIH | Lung-on-a-Chip Disease Mo... (1UG3HL141797-01)

    International audience; There is an urgent need for drugs, therapies and vaccines to be available to protect the human population against COVID-19. One of the first approaches taken in the COVID-19 global response was to consider repurposing licensed drugs. This comment...

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  • publication . Article . 2020
    Open Access
    Authors:
    Sonia Fieulaine; Martin D. Witte; Christopher S. Theile; Maya Ayach; Hidde L. Ploegh; Isabelle Jupin; Stéphane Bressanelli;
    Publisher: Elsevier BV
    Project: ANR | Viro-DUB (ANR-16-CE20-0015)

    International audience; Single-stranded, positive-sense RNA viruses assemble their replication complexes in infected cells from a multi-domain replication polyprotein. This polyprotein usually contains at least one protease whose primary function is to process the polyp...

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  • publication . Other literature type . Article . 2019
    Open Access English
    Authors:
    Yu Wu; Valérie Pons; Romain Noel; Sabrina Kali; Olena Shtanko; Robert A. Davey; Michel R. Popoff; Noël Tordo; Daniel Gillet; Jean-Christophe Cintrat; ...
    Publisher: American Chemical Society
    Project: ANR | LeishmaStop (ANR-18-CE18-0016)

    International audience; The small molecule ABMA has been previously shown to protect cells against multiple toxins and pathogens including virus, intracellular bacteria, and parasite. Its mechanism of action is directly associated with host endolysosomal pathway rather ...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Yu Wu; Valérie Pons; Amélie Goudet; Laetitia Panigai; Annette Fischer; Jo-Ana Herweg; Sabrina Kali; Robert A. Davey; Jérôme Laporte; Céline Bouclier; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | IPS (ANR-11-IDEX-0003), NIH | Receptor Trafficking in E... (5R01AI063513-05), NHMRC | Blue Mountains Cohort Stu... (457349)

    International audience; Intracellular pathogenic microorganisms and toxins exploit host cell mechanisms to enter, exert their deleterious effects as well as hijack host nutrition for their development. A potential approach to treat multiple pathogen infections and that ...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Isabelle Jupin; Maya Ayach; Lucile Jomat; Sonia Fieulaine; Stéphane Bressanelli;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | Viro-DUB (ANR-16-CE20-0015)

    The positive-strand RNA virus Turnip yellow mosaic virus (TYMV) encodes an ovarian tumor (OTU)-like protease/deubiquitinase (PRO/DUB) protein domain involved both in proteolytic processing of the viral polyprotein through its PRO activity, and in removal of ubiquitin ch...

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14 research outcomes, page 1 of 2