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  • Case Reports in Obstetrics and Gyne...

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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Odeh, Maha Ahmad; Abuzneid, Yousef S.; Badareen, Omar; Masarweh, Khaled;

    The coronavirus disease 2019, also called (COVID-19), is an infectious disease which is caused by a virus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first report was in December 2019, and on March 12, 2020, the World Health Organization (WHO) declared this disease a pandemic. COVID-19 targets many major organs causing life-threatening systemic complications. It can cause lung damage and respiratory failure in addition to systemic inflammation and immune dysregulation. Hypercoagulable state and numerous neurological abnormalities also have been reported due to this condition. Going through the literature review, we found some cases of pregnant women with novel coronavirus infection, being mostly mild illnesses, and most of these cases were focused on maternal-fetal transmission and neonatal outcomes. In this case report, we present the case of a COVID-19 positive woman who came to our emergency department at 34 weeks of gestation with tonic-clonic seizures. This case was a challenge for us because we faced a new an unknown manifestation of both COVID and eclampsia.

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    Authors: Akers, Allison; New, Erika P.; Plosker, Shayne; Silva, Celso P.; +2 Authors

    Objective. To report two cases of oocyte retrieval performed in asymptomatic SARS-CoV-2-positive patients. Design. Case report. Setting. Outpatient private practice infertility center. Patients. A 28-year-old woman at risk for OHSS who took her trigger injection prior to testing positive for SARS-CoV-2 and a 19-year-old oncofertility patient who tested positive prior to retrieval due to a family exposure. Both patients were asymptomatic. Main Outcome Measures. Cycle outcomes, patient safety, and staff safety. Results. Both patients underwent successful oocyte retrieval procedures without developing symptoms or complications from COVID-19. No staff members that cared for these patients developed symptoms of COVID-19. Conclusion. Worsening fertility outcomes and potential for psychological and financial burdens to the patient must be balanced with risk of perioperative complications in patients testing positive for SARS-CoV-2. As we continue to provide fertility care in a world with COVID-19, appropriate risk mitigation strategies should be implemented to minimize exposure to SARS-CoV-2.

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    Authors: Rishard, Mohamed(Department of Obstetrics and Gynecology, Faculty of Medicine) Perera, Suren(De Soysa Hospital for Women Kynsey Road, Colombo 08) Jayasinghe, Kushan(De Soysa Hospital for Women Kynsey Road, Colombo 08) Rubasinghe, Amila(De Soysa Hospital for Women Kynsey Road, Colombo 08) Athapaththu, Sanjaya(De Soysa Hospital for Women Kynsey Road, Colombo 08) Edirisinghe, Malindu(De Soysa Hospital for Women Kynsey Road, Colombo 08) Ranaweera, Prabhodana(Department of Obstetrics and Gynecology, Faculty of Medicine) Ranawaka, Tushani(Department of Obstetrics and Gynecology, Faculty of Medicine) Kaluarachchi, Athula(Department of Obstetrics and Gynecology, Faculty of Medicine) Jayawardana, Priyankara(De Soysa Hospital for Women Kynsey Road, Colombo 08) Haniffa, Zacky(De Soysa Hospital for Women Kynsey Road, Colombo 08);

    Based on available literature, pregnant women are at an increased risk of severe illness from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, compared to nonpregnant women. Consequences of coronavirus disease 2019 (COVID-19) in pregnancy have many implications in women’s lives other than unfavorable obstetric outcomes. In addition to managing acute respiratory illness and symptoms, caregivers should be equipped to detect and manage the short-term, intermediate, and long-term consequences of SARS-CoV-2 infection as well. Many pregnant women can remain asymptomatic and continue their pregnancy without being diagnosed. Pregnancy outcomes and consequences of SARS-CoV-2 infected yet asymptomatic mothers have not been very well explained. Reports of a new multisystem inflammatory syndrome in children (MIS-C) and multisystem inflammatory syndrome in adults (MIS-A) following COVID-19 have been described. However, MIS-A in pregnancy is an extremely rare presentation that can cause a huge diagnostic dilemma to caregivers. We describe the successful management of a pregnant woman with MIS-A following SARS-CoV-2 infection.

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    Authors: Connolly, Courtney T.(Department of Obstetrics, Gynecology and Reproductive Science) Grubman, Olivia(Department of Obstetrics, Gynecology and Reproductive Science) Al-Ibraheemi, Zainab(Department of Obstetrics, Gynecology and Reproductive Science) Kushner, Tatyana(Department of Obstetrics, Gynecology and Reproductive Science);

    Background. Alkaline phosphatase (ALP) is an enzyme produced by the liver, small intestine, bone, and kidneys as well as the placenta during pregnancy. ALP levels may increase up to twice the normal limit during pregnancy secondary to placental release and fetal bone growth. Rare case reports of extremely elevated levels of ALP during pregnancy have demonstrated possible association with adverse pregnancy outcomes. Case. The patient is a 36-year-old G2P1001 who was found to have extremely elevated ALP levels during pregnancy after presenting with bilateral lower leg swelling and rash after receiving the Pfizer COVID-19 vaccine. She subsequently developed intrahepatic cholestasis of pregnancy and preeclampsia. ALP peaked at 2,601 U/L immediately prior to delivery at 36 weeks 1 day. She was followed postpartum, and her ALP levels had nearly normalized by 15 weeks postpartum. Conclusion. Our case demonstrates a rare report of an extremely elevated level of ALP in the setting of multiple adverse pregnancy outcomes, including preterm delivery, preeclampsia without severe features, and intrahepatic cholestasis of pregnancy.

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    Authors: Gjakov, Boban(Department of Gynecology and Obstetrics, Brežice General Hospital) Kopač, Darja(Division of Obstetrics and Gynecology, University Medical Center Ljubljana) Vukmanič Pohar, Mateja(Department of Gynecology and Obstetrics, Brežice General Hospital) Lučovnik, Miha(Division of Obstetrics and Gynecology, University Medical Center Ljubljana);

    Maternal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been shown in epidemiological studies to be associated with an increased risk of stillbirth. Several histopathologic features of placental SARS-CoV-2 infection have been proposed as potential causes of fetal death. We present a case of an otherwise healthy G3P1 women with mild symptoms of SARS-CoV-2 infection at 23 6/7 weeks of gestation. At 25 2/7 weeks, she presented with signs and symptoms of preterm labor and decreased fetal movements. Fetal death was diagnosed at admission. Placental pathology showed pronounced placental mixed intervillositis. Inflammatory infiltrate caused extreme narrowing of intervillous space leading to placental malfunction and fetal death. Placental tissue SARS-CoV-2 infection was confirmed by positive immunohistochemistry staining of syncytiotrophoblasts with spike protein antibody. The case presented suggests that SARS-CoV-2 associated inflammatory placental changes pose an elevated risk for the fetus.

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    Authors: Wang, Gloria; Stapley, Eric; Peterson, Sara; Parrott, Jessica; +1 Authors

    Background. Rapid introduction and spread of SARS-CoV-2 have posed unique challenges in understanding the disease, role in vertical transmission, and in developing management. We present a case of a patient with COVID-19 infection and fetus with new-onset fetal SVT. Case. A 26-year-old gravida 4 para 2012 with third trimester COVID-19 infection was diagnosed with new onset fetal SVT. Successful cardioversion was achieved with flecainide. The patient was followed outpatient until induction of labor at 39 and 3/7 weeks of gestational age resulting in an uncomplicated vaginal delivery. Postpartum course was uncomplicated. Conclusion. Fetal SVT is a potential complication of maternal COVID-19 infection. The use of transplacental therapy with flecainide is an appropriate alternative to digoxin in these cases.

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    Authors: Sand, Anna(Department of Women’s and Children’s Health, Karolinska Institutet) Chaireti, Roza(Department of Molecular Medicine and Surgery, Karolinska Institutet) Sennström, Maria(Department of Women’s and Children’s Health, Karolinska Institutet) Pettersson, Karin(Department of Obstetrics and Gynaecology, Karolinska University Hospital) Magnusson, Maria(Department of Molecular Medicine and Surgery, Karolinska Institutet);

    Pregnancy is a naturally occurring hypercoagulable state, and COVID-19 can cause profound changes in the coagulation system associated with thromboinflammation. We report a case of a pregnant woman with moderate symptoms of COVID-19 and a severe coagulopathy with unexpected low levels of fibrinogen and factor VIII as well as atypical thrombelastometry results. She developed a severe placental dysfunction with intrauterine fetal distress and perinatal death. The case did not fulfil the criteria for preeclampsia or sepsis, and the adverse outcome was assessed as a direct effect of the COVID-19 infection with placental insufficiency, despite absence of serious maternal pulmonary symptoms. Atypical persistent coagulopathy may serve as an important marker of a serious obstetrical situation in COVID-19.

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    Authors: Martínez-Varea, Alicia(Department of Obstetrics and Gynecology, University and Polytechnic La Fe Hospital) Desco-Blay, Julia(Department of Obstetrics and Gynecology, University and Polytechnic La Fe Hospital) Monfort, Sagrario(Department of Obstetrics and Gynecology, University and Polytechnic La Fe Hospital) Hueso-Villanueva, María(Department of Obstetrics and Gynecology, University and Polytechnic La Fe Hospital) Perales-Marín, Alfredo(Department of Obstetrics and Gynecology, University and Polytechnic La Fe Hospital) Diago-Almela, Vicente José(Department of Obstetrics and Gynecology, University and Polytechnic La Fe Hospital);

    Background. Vertical transmission of the Coronavirus Disease 2019 (COVID-19) is still controversial. Additionally, the consequences of the infection during pregnancy in the offspring also are unknown. Case. A transitory fetal skin edema and polyhydramnios have been demonstrated by ultrasound in a pregnant patient with COVID-19 after a negative RT-PCR for SARS-CoV-2. The fetal findings presented a spontaneous resolution in utero, and abnormal findings were not found in the newborn. Conclusion. Women who have undergone SARS-CoV-2 infection during pregnancy should receive a subsequent appropriate follow-up in order to clarify the fetal consequences of the novel coronavirus, if any.

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    Authors: Shields, Andrea D.; Byrne, John J.; Munisteri, Meghan; Wood, Michael;

    Introduction. Coronavirus disease 2019 (COVID-19) has been linked to significant cardiovascular complications such as cardiac arrest, which are associated with a poor prognosis in adults. Little is known about the cardiac complications, specifically cardiac arrest, of COVID-19 during pregnancy and postpartum periods. Case. We present a case of survival and full neurological recovery after maternal cardiac arrest associated with COVID-19 in a postpartum female. Her postpartum course was also associated with seizures attributed to posterior reversible encephalopathy syndrome. After 19 days in the hospital, she was discharged home neurologically intact. Conclusion. More information is needed to determine the range of short- and long-term cardiac complications that may be associated with COVID-19 during pregnancy and postpartum. Additionally, pregnant patients with COVID-19 may be more likely to survive cardiac arrest compared to the general population.

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    Authors: Abourida, Yassamine(Department of Anesthesia & Intensive Care Medicine, Faculty of Medicine and Pharmacy of Marrakech) Rebahi, Houssam(Department of Anesthesia & Intensive Care Medicine, Faculty of Medicine and Pharmacy of Marrakech) Oussayeh, Imane(Department of Anesthesia & Intensive Care Medicine, Faculty of Medicine and Pharmacy of Marrakech) Chichou, Hajar(Department of Anesthesia & Intensive Care Medicine, Faculty of Medicine and Pharmacy of Marrakech) Fakhir, Bouchra(Department of Obstetrics & Gynecology, Mother & Child Hospital) Soummani, Abderraouf(Department of Obstetrics & Gynecology, Mother & Child Hospital) Jalal, Hicham(Department of Radiology, Mother & Child Hospital) Bennaoui, Fatiha(Department of Neonatal Intensive Care, Mother & Child Hospital) Slitine, Nadia El Idrissi(Department of Neonatal Intensive Care, Mother & Child Hospital) Maoulainine, Fadl Mrabih Rabou(Department of Neonatal Intensive Care, Mother & Child Hospital) El Adib, Ahmed Rhassane(Department of Anes;

    The scarcity of data concerning pregnant patients gravely infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) makes their management difficult, as most of the reported cases in the literature present mild pneumonia symptoms. The core problem is laying out evidence on coronavirus’s implications on pregnancy and delivery, as well as vertical transmission and neonatal mortality. A healthy 30-year-old pregnant woman, gravida 6, para 4, at 31 weeks of gestation, presented severe pneumonia symptoms promptly complicated with premature rupture of membranes (PROM). A nasopharyngeal swab returned positive for SARS-CoV-2 using reverse transcription polymerase chain reactions (RT-PCR). The parturient underwent a cesarean delivery. This paper is an attempt to outline management of the critical condition of COVID-19 during pregnancy.

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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Odeh, Maha Ahmad; Abuzneid, Yousef S.; Badareen, Omar; Masarweh, Khaled;

    The coronavirus disease 2019, also called (COVID-19), is an infectious disease which is caused by a virus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first report was in December 2019, and on March 12, 2020, the World Health Organization (WHO) declared this disease a pandemic. COVID-19 targets many major organs causing life-threatening systemic complications. It can cause lung damage and respiratory failure in addition to systemic inflammation and immune dysregulation. Hypercoagulable state and numerous neurological abnormalities also have been reported due to this condition. Going through the literature review, we found some cases of pregnant women with novel coronavirus infection, being mostly mild illnesses, and most of these cases were focused on maternal-fetal transmission and neonatal outcomes. In this case report, we present the case of a COVID-19 positive woman who came to our emergency department at 34 weeks of gestation with tonic-clonic seizures. This case was a challenge for us because we faced a new an unknown manifestation of both COVID and eclampsia.

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    Authors: Akers, Allison; New, Erika P.; Plosker, Shayne; Silva, Celso P.; +2 Authors

    Objective. To report two cases of oocyte retrieval performed in asymptomatic SARS-CoV-2-positive patients. Design. Case report. Setting. Outpatient private practice infertility center. Patients. A 28-year-old woman at risk for OHSS who took her trigger injection prior to testing positive for SARS-CoV-2 and a 19-year-old oncofertility patient who tested positive prior to retrieval due to a family exposure. Both patients were asymptomatic. Main Outcome Measures. Cycle outcomes, patient safety, and staff safety. Results. Both patients underwent successful oocyte retrieval procedures without developing symptoms or complications from COVID-19. No staff members that cared for these patients developed symptoms of COVID-19. Conclusion. Worsening fertility outcomes and potential for psychological and financial burdens to the patient must be balanced with risk of perioperative complications in patients testing positive for SARS-CoV-2. As we continue to provide fertility care in a world with COVID-19, appropriate risk mitigation strategies should be implemented to minimize exposure to SARS-CoV-2.

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    Authors: Rishard, Mohamed(Department of Obstetrics and Gynecology, Faculty of Medicine) Perera, Suren(De Soysa Hospital for Women Kynsey Road, Colombo 08) Jayasinghe, Kushan(De Soysa Hospital for Women Kynsey Road, Colombo 08) Rubasinghe, Amila(De Soysa Hospital for Women Kynsey Road, Colombo 08) Athapaththu, Sanjaya(De Soysa Hospital for Women Kynsey Road, Colombo 08) Edirisinghe, Malindu(De Soysa Hospital for Women Kynsey Road, Colombo 08) Ranaweera, Prabhodana(Department of Obstetrics and Gynecology, Faculty of Medicine) Ranawaka, Tushani(Department of Obstetrics and Gynecology, Faculty of Medicine) Kaluarachchi, Athula(Department of Obstetrics and Gynecology, Faculty of Medicine) Jayawardana, Priyankara(De Soysa Hospital for Women Kynsey Road, Colombo 08) Haniffa, Zacky(De Soysa Hospital for Women Kynsey Road, Colombo 08);

    Based on available literature, pregnant women are at an increased risk of severe illness from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, compared to nonpregnant women. Consequences of coronavirus disease 2019 (COVID-19) in pregnancy have many implications in women’s lives other than unfavorable obstetric outcomes. In addition to managing acute respiratory illness and symptoms, caregivers should be equipped to detect and manage the short-term, intermediate, and long-term consequences of SARS-CoV-2 infection as well. Many pregnant women can remain asymptomatic and continue their pregnancy without being diagnosed. Pregnancy outcomes and consequences of SARS-CoV-2 infected yet asymptomatic mothers have not been very well explained. Reports of a new multisystem inflammatory syndrome in children (MIS-C) and multisystem inflammatory syndrome in adults (MIS-A) following COVID-19 have been described. However, MIS-A in pregnancy is an extremely rare presentation that can cause a huge diagnostic dilemma to caregivers. We describe the successful management of a pregnant woman with MIS-A following SARS-CoV-2 infection.

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    Authors: Connolly, Courtney T.(Department of Obstetrics, Gynecology and Reproductive Science) Grubman, Olivia(Department of Obstetrics, Gynecology and Reproductive Science) Al-Ibraheemi, Zainab(Department of Obstetrics, Gynecology and Reproductive Science) Kushner, Tatyana(Department of Obstetrics, Gynecology and Reproductive Science);

    Background. Alkaline phosphatase (ALP) is an enzyme produced by the liver, small intestine, bone, and kidneys as well as the placenta during pregnancy. ALP levels may increase up to twice the normal limit during pregnancy secondary to placental release and fetal bone growth. Rare case reports of extremely elevated levels of ALP during pregnancy have demonstrated possible association with adverse pregnancy outcomes. Case. The patient is a 36-year-old G2P1001 who was found to have extremely elevated ALP levels during pregnancy after presenting with bilateral lower leg swelling and rash after receiving the Pfizer COVID-19 vaccine. She subsequently developed intrahepatic cholestasis of pregnancy and preeclampsia. ALP peaked at 2,601 U/L immediately prior to delivery at 36 weeks 1 day. She was followed postpartum, and her ALP levels had nearly normalized by 15 weeks postpartum. Conclusion. Our case demonstrates a rare report of an extremely elevated level of ALP in the setting of multiple adverse pregnancy outcomes, including preterm delivery, preeclampsia without severe features, and intrahepatic cholestasis of pregnancy.

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    Authors: Gjakov, Boban(Department of Gynecology and Obstetrics, Brežice General Hospital) Kopač, Darja(Division of Obstetrics and Gynecology, University Medical Center Ljubljana) Vukmanič Pohar, Mateja(Department of Gynecology and Obstetrics, Brežice General Hospital) Lučovnik, Miha(Division of Obstetrics and Gynecology, University Medical Center Ljubljana);

    Maternal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been shown in epidemiological studies to be associated with an increased risk of stillbirth. Several histopathologic features of placental SARS-CoV-2 infection have been proposed as potential causes of fetal death. We present a case of an otherwise healthy G3P1 women with mild symptoms of SARS-CoV-2 infection at 23 6/7 weeks of gestation. At 25 2/7 weeks, she presented with signs and symptoms of preterm labor and decreased fetal movements. Fetal death was diagnosed at admission. Placental pathology showed pronounced placental mixed intervillositis. Inflammatory infiltrate caused extreme narrowing of intervillous space leading to placental malfunction and fetal death. Placental tissue SARS-CoV-2 infection was confirmed by positive immunohistochemistry staining of syncytiotrophoblasts with spike protein antibody. The case presented suggests that SARS-CoV-2 associated inflammatory placental changes pose an elevated risk for the fetus.

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    Authors: Wang, Gloria; Stapley, Eric; Peterson, Sara; Parrott, Jessica; +1 Authors

    Background. Rapid introduction and spread of SARS-CoV-2 have posed unique challenges in understanding the disease, role in vertical transmission, and in developing management. We present a case of a patient with COVID-19 infection and fetus with new-onset fetal SVT. Case. A 26-year-old gravida 4 para 2012 with third trimester COVID-19 infection was diagnosed with new onset fetal SVT. Successful cardioversion was achieved with flecainide. The patient was followed outpatient until induction of labor at 39 and 3/7 weeks of gestational age resulting in an uncomplicated vaginal delivery. Postpartum course was uncomplicated. Conclusion. Fetal SVT is a potential complication of maternal COVID-19 infection. The use of transplacental therapy with flecainide is an appropriate alternative to digoxin in these cases.

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    Authors: Sand, Anna(Department of Women’s and Children’s Health, Karolinska Institutet) Chaireti, Roza(Department of Molecular Medicine and Surgery, Karolinska Institutet) Sennström, Maria(Department of Women’s and Children’s Health, Karolinska Institutet) Pettersson, Karin(Department of Obstetrics and Gynaecology, Karolinska University Hospital) Magnusson, Maria(Department of Molecular Medicine and Surgery, Karolinska Institutet);

    Pregnancy is a naturally occurring hypercoagulable state, and COVID-19 can cause profound changes in the coagulation system associated with thromboinflammation. We report a case of a pregnant woman with moderate symptoms of COVID-19 and a severe coagulopathy with unexpected low levels of fibrinogen and factor VIII as well as atypical thrombelastometry results. She developed a severe placental dysfunction with intrauterine fetal distress and perinatal death. The case did not fulfil the criteria for preeclampsia or sepsis, and the adverse outcome was assessed as a direct effect of the COVID-19 infection with placental insufficiency, despite absence of serious maternal pulmonary symptoms. Atypical persistent coagulopathy may serve as an important marker of a serious obstetrical situation in COVID-19.

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    Authors: Martínez-Varea, Alicia(Department of Obstetrics and Gynecology, University and Polytechnic La Fe Hospital) Desco-Blay, Julia(Department of Obstetrics and Gynecology, University and Polytechnic La Fe Hospital) Monfort, Sagrario(Department of Obstetrics and Gynecology, University and Polytechnic La Fe Hospital) Hueso-Villanueva, María(Department of Obstetrics and Gynecology, University and Polytechnic La Fe Hospital) Perales-Marín, Alfredo(Department of Obstetrics and Gynecology, University and Polytechnic La Fe Hospital) Diago-Almela, Vicente José(Department of Obstetrics and Gynecology, University and Polytechnic La Fe Hospital);

    Background. Vertical transmission of the Coronavirus Disease 2019 (COVID-19) is still controversial. Additionally, the consequences of the infection during pregnancy in the offspring also are unknown. Case. A transitory fetal skin edema and polyhydramnios have been demonstrated by ultrasound in a pregnant patient with COVID-19 after a negative RT-PCR for SARS-CoV-2. The fetal findings presented a spontaneous resolution in utero, and abnormal findings were not found in the newborn. Conclusion. Women who have undergone SARS-CoV-2 infection during pregnancy should receive a subsequent appropriate follow-up in order to clarify the fetal consequences of the novel coronavirus, if any.

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    Authors: Shields, Andrea D.; Byrne, John J.; Munisteri, Meghan; Wood, Michael;

    Introduction. Coronavirus disease 2019 (COVID-19) has been linked to significant cardiovascular complications such as cardiac arrest, which are associated with a poor prognosis in adults. Little is known about the cardiac complications, specifically cardiac arrest, of COVID-19 during pregnancy and postpartum periods. Case. We present a case of survival and full neurological recovery after maternal cardiac arrest associated with COVID-19 in a postpartum female. Her postpartum course was also associated with seizures attributed to posterior reversible encephalopathy syndrome. After 19 days in the hospital, she was discharged home neurologically intact. Conclusion. More information is needed to determine the range of short- and long-term cardiac complications that may be associated with COVID-19 during pregnancy and postpartum. Additionally, pregnant patients with COVID-19 may be more likely to survive cardiac arrest compared to the general population.

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    Authors: Abourida, Yassamine(Department of Anesthesia & Intensive Care Medicine, Faculty of Medicine and Pharmacy of Marrakech) Rebahi, Houssam(Department of Anesthesia & Intensive Care Medicine, Faculty of Medicine and Pharmacy of Marrakech) Oussayeh, Imane(Department of Anesthesia & Intensive Care Medicine, Faculty of Medicine and Pharmacy of Marrakech) Chichou, Hajar(Department of Anesthesia & Intensive Care Medicine, Faculty of Medicine and Pharmacy of Marrakech) Fakhir, Bouchra(Department of Obstetrics & Gynecology, Mother & Child Hospital) Soummani, Abderraouf(Department of Obstetrics & Gynecology, Mother & Child Hospital) Jalal, Hicham(Department of Radiology, Mother & Child Hospital) Bennaoui, Fatiha(Department of Neonatal Intensive Care, Mother & Child Hospital) Slitine, Nadia El Idrissi(Department of Neonatal Intensive Care, Mother & Child Hospital) Maoulainine, Fadl Mrabih Rabou(Department of Neonatal Intensive Care, Mother & Child Hospital) El Adib, Ahmed Rhassane(Department of Anes;

    The scarcity of data concerning pregnant patients gravely infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) makes their management difficult, as most of the reported cases in the literature present mild pneumonia symptoms. The core problem is laying out evidence on coronavirus’s implications on pregnancy and delivery, as well as vertical transmission and neonatal mortality. A healthy 30-year-old pregnant woman, gravida 6, para 4, at 31 weeks of gestation, presented severe pneumonia symptoms promptly complicated with premature rupture of membranes (PROM). A nasopharyngeal swab returned positive for SARS-CoV-2 using reverse transcription polymerase chain reactions (RT-PCR). The parturient underwent a cesarean delivery. This paper is an attempt to outline management of the critical condition of COVID-19 during pregnancy.

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