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  • COVID-19
  • 2012-2021
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Terence Kee; Jong Cheol Jeong; Harun Ur-Rashid; Nura Afza Salma Begum; +11 Authors

    Background : Asia is the global epicenter of the coronavirus disease 2019 (COVID-19) pandemic; however, COVID-19-related mortality in Asia remains lower than in other parts of the world. It is uncertain whether the mortality of COVID-19-infected kidney transplant recipients (KTXs) from Asia follows the lower mortality trends of the younger Asian population. Methods : Specific transplant centers from countries in the Asian Society of Transplantation were invited to participate in a study to examine the epidemiology, clinical features, natural history, and outcomes of COVID-19 infections in KTXs. Data were analyzed and compared with those of large cohort studies from other countries. Results : The study population was 87 KTXs from nine hospitals in seven Asian countries. Within the study population, 9% were aged 60 years and older, and 79% had at least one comorbidity. The majority of patients (69%) presented with mild-to-moderate COVID-19 severity. Disease progression was more frequently encountered among those with moderate or severe infection (23%) and non-survivors (55%). The mortality rate was 23% (n=20) and differed according to the level of care: 12% (n=1/8), 15% (n=10/67), and 100% (n=9/9) of patients managed as outpatients, in the general ward, and in the intensive care unit, respectively. Disease severity at the time of presentation was an independent predictor of mortality. Compared with the mortality rates in other studies worldwide, mortality rates in the current study were comparable. Conclusions: Mortality in Asian KTXs who were infected with COVID-19 remains high and could be related to comorbidity burden and the constraints of the general healthcare system when the COVID-19 caseload is high.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Korean Journal of Tr...arrow_drop_down
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    Korean Journal of Transplantation
    Article . 2021
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    Korean Journal of Transplantation
    Article . 2021 . Peer-reviewed
    License: CC BY NC
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    Korean Journal of Transplantation
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Korean Journal of Tr...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      Korean Journal of Transplantation
      Article . 2021
      Data sources: DOAJ
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      Korean Journal of Transplantation
      Article . 2021 . Peer-reviewed
      License: CC BY NC
      Data sources: Crossref
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      Korean Journal of Transplantation
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Masmoudi, Slim;

    This study was conducted to assess the psychological distress in the general population of Tunisia during the pandemic of COVID-19 and examines how awareness of the disease, emotional experience, and motivation shaped the behavior toward this outbreak. The study covers 1492 Tunisian participants. Gender effects and age limits were studied in relation with the seriousness of the disease and lockdown impacts. The data were analyzed and interpreted using the chi-square test, ANOVA, path analysis (PA), and confirmatory factor analysis (CFA). We found a significant effect of gender and age on the awareness of the pandemic dangerousness, the attitude, and the commitment to respect the preventive measures. Women are significantly more aware and committed than men to respect preventive health measures. The 35–45 age group showed more awareness and dedication than the other age groups, while the 20–35 age group showed the most less promise. PA and CFA results showed how awareness, emotion, and motivation shaped behavior toward COVID-19. This study provides practical and relevant information on behavior change during a pandemic crisis, which can orient communication campaigns and help policymakers.

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    Frontiers in Public Health
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    License: CC BY
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    DOAJ
    Article . 2021
    Data sources: DOAJ
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    Frontiers in Public Health
    Article . 2021 . Peer-reviewed
    License: CC BY
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      Frontiers in Public Health
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      DOAJ
      Article . 2021
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      Frontiers in Public Health
      Article . 2021 . Peer-reviewed
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Shereen E. Tawfeek; Ayat M. Domouky; Reham H. Abdel-Kareem;

    Ivermectin (Ive) has exceedingly efficient against several microorganisms including viruses; therefore, it could help as a potential treatment of COVID-19. Because of increasing consumption of ivermectin and vitamin C (Vit.C) in hope to treat COVID-19, and because of ivermectin nephrotoxic effects have not been fully clarified especially in juvenile age, it was conducted to examine the histopathological and biochemical effects of ivermectin on adult and juvenile kidneys, and to assess the possible protective role of Vit.C against this potential toxicity. Rats were divided to 4 subgroups (Control subgroup, Vit.C subgroup, Ive subgroup, and Vit.C+Ive subgroup), 1 week after 4 doses of ivermectin (0.4 mg/kg Ive±1.25 mg/kg Vit.C), blood samples obtained for assessment of kidney function test, part of kidneys prepared for determination of matrix metalloproteinase-9 and antioxidant enzymes essay. Other parts prepared for histopathological and ultrastructural examination. Results showed that administration of ivermectin led to attenuation in kidney function and in activities of the antioxidant enzymes and increase in matrix metalloproteinase-9 activity. In addition, there were histological damages (shrunken glomeruli, widened urinary space, cytoplasmic vacuolation and pyknotic nuclei with epithelial exfoliation, extravasated blood, and mononuclear cell infiltration) and immunohistochemistry revealed increase in percentage of Bax proapoptotic protein expression. Also, ultrastructure examination showed alteration in cell architecture. All these changes were more obvious in juvenile group while co-administration of Vit.C led to significant protection more in adult group. In conclusion, Ivermectin should be used cautiously especially in juvenile age, and co-administration of Vit.C is highly recommended.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Europe PubMed Centra...arrow_drop_down
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    Anatomy & Cell Biology
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    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Anatomy & Cell Biology
    Article . 2021 . Peer-reviewed
    License: CC BY NC
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      Anatomy & Cell Biology
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      Anatomy & Cell Biology
      Article . 2021 . Peer-reviewed
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Jung-Ja Hong; Shin Hwang; Deog-Bok Moon; Young Hoon Kim; +5 Authors

    Background : The severity of the coronavirus disease 2019 (COVID-19) pandemic has discouraged organ donation. However, the prevalence of COVID-19 in Korea was much lower in comparison to Western countries. With this, the authors decided to determine the real-world impact of COVID-19 on organ donation and transplantation in Korea. Methods : The number of kidney transplantations (KTs) and liver transplantations (LTs) performed in 2020 were compared with those in 2019 using the Korean Network for Organ Sharing database and Asan Medical Center (AMC) database. Results : The annual number of deceased donors (DDs) was 450 in 2019 compared to 478 in 2020. Monthly DD number was 37.5±5.9 in 2019 and 39.8±4.4 in 2020 (P=0.284). Annual number of DD kidney transplant (DDKT) was 794 in 2019 and 848 in 2020, and monthly number was 66.1±10.4 in 2019 and 70.7±9.8 in 2020 (P=0.285). The annual number of DDLT was 391 in 2019 and 395 in 2020, and the monthly number was 32.6±5.7, 2019 and 32.9±4.7 in 2020 (P=0.877). The annual number of living donor (LD) KT was 2,293 in 2019 and 1,432 in 2020, and the monthly number was 191.1±19.5 in 2019 and 119.3±11.7 in 2020 (P<0.001). Annual number of living donor LDLT was 1,577 in 2019 and 1,146 in 2020, and monthly number was 131.4±18.1 in 2019 and 95.5±8.0 in 2020 (P<0.001). In the AMC, not all types of KT and LT changed significantly. Conclusions: The results of this study indicate that the number of DD organ transplantations remained stable in Korea in 2020, but the number of LD organ transplantations was significantly reduced. However, the number of organ transplantations did not change in the AMC.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Korean Journal of Tr...arrow_drop_down
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    Korean Journal of Transplantation
    Article . 2021 . Peer-reviewed
    License: CC BY NC
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    Korean Journal of Transplantation
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    Korean Journal of Transplantation
    Article . 2021
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Korean Journal of Tr...arrow_drop_down
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      Korean Journal of Transplantation
      Article . 2021 . Peer-reviewed
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      Korean Journal of Transplantation
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      Korean Journal of Transplantation
      Article . 2021
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    Authors: Mansour A. Alyahya; Ibrahim A. Elshaer; Abu Elnasr E. Sobaih;

    The COVID-19 pandemic has severe psychological and psychosocial impacts on hotel workers. This study examines the causal direct impact of both job insecurity and distributive injustice, which were common in hotels post COVID-19, on social loafing behavior among hotel workers, and the indirect impact through turnover intention. Data were collected from 850 hotels workers in the Kingdom of Saudi Arabia. Using results obtained through structural equation modeling (SEM), the spread of both job insecurity and distributive injustice positively and significantly influences turnover intention among hotel workers post the COVID-19 pandemic. The results also found that turnover intention fully mediates the influence of both distributive injustices on social loafing behavior. On the other side, it partially mediates job insecurity on social loafing behavior among hotel workers. Implications for scholars and practitioners as well as limitations of current research are discussed.

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    Authors: Areej Yousef Ahmed Hakim;

    The current study aimed to identify the quality level of academic life during COVID-19 pandemic from students' perception of Taibah University, Yanbu branch. To this end, a descriptive approach was used to answer the following main research question: What is the quality level of academic life during COVID-19 pandemic from students' perception of Taibah University? The study tool consisted of a questionnaire to measure the quality level of the students’ academic life. The tool was ensured for reliability and validity and composed of three sections that contained indicators to measure the quality of academic life; academic practices, academic satisfaction, and academic support. The sample of the study consisted of 187 male and female students. Results showed high perceptions for the respondents in the quality of academic practices section (M=4.15, SD=1.03). The statement No.9 entitles “Rate the precautionary actions provided to you to activate the online education as an alternative to face-to-face education during COVID-19 pandemic” obtained the highest rank (M=4.63). The second section that measured the level of academic satisfaction recorded (M=1.76, SD=1.10), obtaining 58.71%. The statement 6 entitles “I felt my love to home increased during COVID-19 pandemic” obtained the highest rank (M=4.63, SD=.81, 98.93%). The academic support dimension recorded (M=4.33, SD=.93), Indicating that the level of academic support for students during COVID-19 pandemic was excellent (86.65%) as perceived by the study sample. The statement 5 which entitles “Rate the extent to benefit from academic counseling during COVID-19 pandemic” got the highest rank (M=4.67, SD=.72, 93.485). The most challenges encountered the students gradually categorized from the highest to the lowest were the poor Internet network, non-availability of laptop computers, low experience in working with blackboard, and poor technical experience. The study recommended the significance of academic support and suggested doing further studies on and the reality of quality of academic life from faculty members perspectives and the role of precautionary health during COID-19 pandemic to enhance the national loyalty for the university students.

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    Authors: Ahmed S. Ali; Torki Al-Zughaibi; Assmaa A. Shaker;

    Many investigations have confirmed the link between a substance use disorder (SUD) and the COVID-19 pandemic's increased risk of infection and consequences. This narrative review aims to understand these issues from a pharmacological standpoint, as well as the pandemic's impact on forensic medicine. Research and review articles included in this review were selected through an extensive search of databases such as PubMed and the use of appropriate keywords e.g. “substance use disorder” and “COVID-19”. Due to a weakened immune system and degeneration of the respiratory system's defense systems, SUDs have been shown to increase the risk of COVID-19 infection. Furthermore, some substances raise pro-inflammatory mediators, exposing the body to a cytokine storm. SUD frequently causes secondary comorbidities, such as the liver, lung and cardiovascular disease, complicating the treatment of COVID-19 infections. Some misused substances can compromise the treatment's effectiveness or safety. This study also looked at the effects of the pandemic on forensic medicine. It underlines the importance of developing safe forensic examination procedures and methodologies during pandemics. The use of narcotic substances was documented as one of the reasons for the increase in the frequency of COVID-19 and the severity of its repercussions.

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    Arab Journal of Forensic Sciences &amp; Forensic Medicine
    Article . 2021 . Peer-reviewed
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      Arab Journal of Forensic Sciences &amp; Forensic Medicine
      Article . 2021 . Peer-reviewed
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    Authors: Rawabi Aljumaiah; Wael Alturaiki; Bandar Alosaimi;

    Besides respiratory symptoms, COVID-19 disease has a wide range of clinical, subclinical, and atypical presentations reported previously. Here, we report the case report of a middle-aged man, with no previous known medical illness, who presented with a 5-day-history of anxiety, fever, confusion, and hallucinations. Patient’s SARS-CoV-2 polymerase chain reaction test was positive, and he underwent daily vital signs and respiratory, cardiovascular, and abdominal examinations. Chest radiography, electrocardiogram, microbial culture, biochemistry, and toxicology tests were also investigated. In this report, a case of COVID-19 is described with an unusual presentation of confusion and hallucinations in the absence of severe upper respiratory or constitutional symptoms. The earlier recognition of atypical manifestation, the safer the practice, with optimal timely diagnosis, and less anticipated outbreaks in healthcare facilities. Further studies are needed to establish the underlying pathophysiological mechanisms involved.

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    Case Reports in Psychiatry
    Article . 2021 . Peer-reviewed
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      Case Reports in Psychiatry
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    Authors: ALOTAIBI FAISAL;

    Abstract The epidemic of COVID-19 spread quickly through China and engulfed all of the countries across the globe. Several advances have been made in understanding the novel coronavirus’s pathophysiology and in the development of newer diagnostics with pinpoint accuracy. Several newer therapeutic methods have either been accepted or are awaiting acceptance. In many countries, vaccination programs have been rolled out. Despite all these efforts, coronavirus still exists, though with lesser propensity. Multiple new forms of the novel coronavirus unexpectedly appeared in various areas of the world, undermining previously existing diagnosis and care protocols. This article highlights our understanding of the novel coronavirus’s symptoms in brief, pathogenesis, diagnostics, and therapeutic strategies to contain COVID-19. The clinical findings, including serological, radiological, and other advanced diagnostic strategies, contributed much to control the disease. To date, supportive interventions have been used in tandem with potent antiviral therapies such as remdesivir, lopinavir/ritonavir, or corticosteroids with a level of trust in the care of COVID-19 patients. However, in several areas of the world, vaccination initiatives took place; the vaccines’ safety and efficacy to control the outbreak is yet to be identified. This review concludes that improvement in therapies and diagnostics for COVID-19 must continually be explored as new variants constantly emerge.

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    Acta Pharmaceutica
    Article . 2021 . Peer-reviewed
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    Acta Pharmaceutica
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      Acta Pharmaceutica
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  • Authors: Asma Shakoor; Aleeza Sana; Hammad Hassan; Farhan Ahmed; +3 Authors

    Objective: COVID-19 began in Wuhan, China, and has since spread around the world, becoming the leading cause of death in 2020 from the day it infected the first human. The aim of this study was to determine how well the general public knew about COVID-19 and to investigate their attitudes and practices. Methods: This descriptive cross-sectional survey was conducted for the period of two months from July 2021 to August 2021.The sample size was 907. Questionnaire was divided into three components and gathered information about demographic data, knowledge of COVID-19 and their practice section that involves steps taken by the individual to prevent contracting the infection and data was analysed. Results: In this study, 51 %( 463) participants were males and 49 %( 444) were females. 91% of respondents responded that they are aware of the fact that covid-19 is contagious infection. 54% of candidates take preventive measures such as they wash hands frequently, use hand sanitizer, steam inhalation, wear facemasks etc. 50% of respondents are practicing social distance through only going out for essentials for food items, while 16% do social distancing by working from home. Conclusion: The participants indicated a high level of awareness about the COVID-19 pandemic, its outbreak, and basic information about it. Educated people are more likely to believe the scientific facts thus more compliance with preventive measures.The majority of them were satisfied with the actions done by the Government of Punjab. Keywords: Awareness; Attitude; Practices; COVID-19; Public.

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    Authors: Terence Kee; Jong Cheol Jeong; Harun Ur-Rashid; Nura Afza Salma Begum; +11 Authors

    Background : Asia is the global epicenter of the coronavirus disease 2019 (COVID-19) pandemic; however, COVID-19-related mortality in Asia remains lower than in other parts of the world. It is uncertain whether the mortality of COVID-19-infected kidney transplant recipients (KTXs) from Asia follows the lower mortality trends of the younger Asian population. Methods : Specific transplant centers from countries in the Asian Society of Transplantation were invited to participate in a study to examine the epidemiology, clinical features, natural history, and outcomes of COVID-19 infections in KTXs. Data were analyzed and compared with those of large cohort studies from other countries. Results : The study population was 87 KTXs from nine hospitals in seven Asian countries. Within the study population, 9% were aged 60 years and older, and 79% had at least one comorbidity. The majority of patients (69%) presented with mild-to-moderate COVID-19 severity. Disease progression was more frequently encountered among those with moderate or severe infection (23%) and non-survivors (55%). The mortality rate was 23% (n=20) and differed according to the level of care: 12% (n=1/8), 15% (n=10/67), and 100% (n=9/9) of patients managed as outpatients, in the general ward, and in the intensive care unit, respectively. Disease severity at the time of presentation was an independent predictor of mortality. Compared with the mortality rates in other studies worldwide, mortality rates in the current study were comparable. Conclusions: Mortality in Asian KTXs who were infected with COVID-19 remains high and could be related to comorbidity burden and the constraints of the general healthcare system when the COVID-19 caseload is high.

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    Korean Journal of Transplantation
    Article . 2021
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    Korean Journal of Transplantation
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    Korean Journal of Transplantation
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      Korean Journal of Transplantation
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      Korean Journal of Transplantation
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      Korean Journal of Transplantation
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    Authors: Masmoudi, Slim;

    This study was conducted to assess the psychological distress in the general population of Tunisia during the pandemic of COVID-19 and examines how awareness of the disease, emotional experience, and motivation shaped the behavior toward this outbreak. The study covers 1492 Tunisian participants. Gender effects and age limits were studied in relation with the seriousness of the disease and lockdown impacts. The data were analyzed and interpreted using the chi-square test, ANOVA, path analysis (PA), and confirmatory factor analysis (CFA). We found a significant effect of gender and age on the awareness of the pandemic dangerousness, the attitude, and the commitment to respect the preventive measures. Women are significantly more aware and committed than men to respect preventive health measures. The 35–45 age group showed more awareness and dedication than the other age groups, while the 20–35 age group showed the most less promise. PA and CFA results showed how awareness, emotion, and motivation shaped behavior toward COVID-19. This study provides practical and relevant information on behavior change during a pandemic crisis, which can orient communication campaigns and help policymakers.

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    Frontiers in Public Health
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    DOAJ
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    Frontiers in Public Health
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      Frontiers in Public Health
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    Authors: Shereen E. Tawfeek; Ayat M. Domouky; Reham H. Abdel-Kareem;

    Ivermectin (Ive) has exceedingly efficient against several microorganisms including viruses; therefore, it could help as a potential treatment of COVID-19. Because of increasing consumption of ivermectin and vitamin C (Vit.C) in hope to treat COVID-19, and because of ivermectin nephrotoxic effects have not been fully clarified especially in juvenile age, it was conducted to examine the histopathological and biochemical effects of ivermectin on adult and juvenile kidneys, and to assess the possible protective role of Vit.C against this potential toxicity. Rats were divided to 4 subgroups (Control subgroup, Vit.C subgroup, Ive subgroup, and Vit.C+Ive subgroup), 1 week after 4 doses of ivermectin (0.4 mg/kg Ive±1.25 mg/kg Vit.C), blood samples obtained for assessment of kidney function test, part of kidneys prepared for determination of matrix metalloproteinase-9 and antioxidant enzymes essay. Other parts prepared for histopathological and ultrastructural examination. Results showed that administration of ivermectin led to attenuation in kidney function and in activities of the antioxidant enzymes and increase in matrix metalloproteinase-9 activity. In addition, there were histological damages (shrunken glomeruli, widened urinary space, cytoplasmic vacuolation and pyknotic nuclei with epithelial exfoliation, extravasated blood, and mononuclear cell infiltration) and immunohistochemistry revealed increase in percentage of Bax proapoptotic protein expression. Also, ultrastructure examination showed alteration in cell architecture. All these changes were more obvious in juvenile group while co-administration of Vit.C led to significant protection more in adult group. In conclusion, Ivermectin should be used cautiously especially in juvenile age, and co-administration of Vit.C is highly recommended.

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    Anatomy & Cell Biology
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    Anatomy & Cell Biology
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      Anatomy & Cell Biology
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      Anatomy & Cell Biology
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    Authors: Jung-Ja Hong; Shin Hwang; Deog-Bok Moon; Young Hoon Kim; +5 Authors

    Background : The severity of the coronavirus disease 2019 (COVID-19) pandemic has discouraged organ donation. However, the prevalence of COVID-19 in Korea was much lower in comparison to Western countries. With this, the authors decided to determine the real-world impact of COVID-19 on organ donation and transplantation in Korea. Methods : The number of kidney transplantations (KTs) and liver transplantations (LTs) performed in 2020 were compared with those in 2019 using the Korean Network for Organ Sharing database and Asan Medical Center (AMC) database. Results : The annual number of deceased donors (DDs) was 450 in 2019 compared to 478 in 2020. Monthly DD number was 37.5±5.9 in 2019 and 39.8±4.4 in 2020 (P=0.284). Annual number of DD kidney transplant (DDKT) was 794 in 2019 and 848 in 2020, and monthly number was 66.1±10.4 in 2019 and 70.7±9.8 in 2020 (P=0.285). The annual number of DDLT was 391 in 2019 and 395 in 2020, and the monthly number was 32.6±5.7, 2019 and 32.9±4.7 in 2020 (P=0.877). The annual number of living donor (LD) KT was 2,293 in 2019 and 1,432 in 2020, and the monthly number was 191.1±19.5 in 2019 and 119.3±11.7 in 2020 (P<0.001). Annual number of living donor LDLT was 1,577 in 2019 and 1,146 in 2020, and monthly number was 131.4±18.1 in 2019 and 95.5±8.0 in 2020 (P<0.001). In the AMC, not all types of KT and LT changed significantly. Conclusions: The results of this study indicate that the number of DD organ transplantations remained stable in Korea in 2020, but the number of LD organ transplantations was significantly reduced. However, the number of organ transplantations did not change in the AMC.

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    Korean Journal of Transplantation
    Article . 2021 . Peer-reviewed
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    Korean Journal of Transplantation
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    Korean Journal of Transplantation
    Article . 2021
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      Korean Journal of Transplantation
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      Korean Journal of Transplantation
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      Korean Journal of Transplantation
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    Authors: Mansour A. Alyahya; Ibrahim A. Elshaer; Abu Elnasr E. Sobaih;

    The COVID-19 pandemic has severe psychological and psychosocial impacts on hotel workers. This study examines the causal direct impact of both job insecurity and distributive injustice, which were common in hotels post COVID-19, on social loafing behavior among hotel workers, and the indirect impact through turnover intention. Data were collected from 850 hotels workers in the Kingdom of Saudi Arabia. Using results obtained through structural equation modeling (SEM), the spread of both job insecurity and distributive injustice positively and significantly influences turnover intention among hotel workers post the COVID-19 pandemic. The results also found that turnover intention fully mediates the influence of both distributive injustices on social loafing behavior. On the other side, it partially mediates job insecurity on social loafing behavior among hotel workers. Implications for scholars and practitioners as well as limitations of current research are discussed.

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    Authors: Areej Yousef Ahmed Hakim;

    The current study aimed to identify the quality level of academic life during COVID-19 pandemic from students' perception of Taibah University, Yanbu branch. To this end, a descriptive approach was used to answer the following main research question: What is the quality level of academic life during COVID-19 pandemic from students' perception of Taibah University? The study tool consisted of a questionnaire to measure the quality level of the students’ academic life. The tool was ensured for reliability and validity and composed of three sections that contained indicators to measure the quality of academic life; academic practices, academic satisfaction, and academic support. The sample of the study consisted of 187 male and female students. Results showed high perceptions for the respondents in the quality of academic practices section (M=4.15, SD=1.03). The statement No.9 entitles “Rate the precautionary actions provided to you to activate the online education as an alternative to face-to-face education during COVID-19 pandemic” obtained the highest rank (M=4.63). The second section that measured the level of academic satisfaction recorded (M=1.76, SD=1.10), obtaining 58.71%. The statement 6 entitles “I felt my love to home increased during COVID-19 pandemic” obtained the highest rank (M=4.63, SD=.81, 98.93%). The academic support dimension recorded (M=4.33, SD=.93), Indicating that the level of academic support for students during COVID-19 pandemic was excellent (86.65%) as perceived by the study sample. The statement 5 which entitles “Rate the extent to benefit from academic counseling during COVID-19 pandemic” got the highest rank (M=4.67, SD=.72, 93.485). The most challenges encountered the students gradually categorized from the highest to the lowest were the poor Internet network, non-availability of laptop computers, low experience in working with blackboard, and poor technical experience. The study recommended the significance of academic support and suggested doing further studies on and the reality of quality of academic life from faculty members perspectives and the role of precautionary health during COID-19 pandemic to enhance the national loyalty for the university students.

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    Authors: Ahmed S. Ali; Torki Al-Zughaibi; Assmaa A. Shaker;

    Many investigations have confirmed the link between a substance use disorder (SUD) and the COVID-19 pandemic's increased risk of infection and consequences. This narrative review aims to understand these issues from a pharmacological standpoint, as well as the pandemic's impact on forensic medicine. Research and review articles included in this review were selected through an extensive search of databases such as PubMed and the use of appropriate keywords e.g. “substance use disorder” and “COVID-19”. Due to a weakened immune system and degeneration of the respiratory system's defense systems, SUDs have been shown to increase the risk of COVID-19 infection. Furthermore, some substances raise pro-inflammatory mediators, exposing the body to a cytokine storm. SUD frequently causes secondary comorbidities, such as the liver, lung and cardiovascular disease, complicating the treatment of COVID-19 infections. Some misused substances can compromise the treatment's effectiveness or safety. This study also looked at the effects of the pandemic on forensic medicine. It underlines the importance of developing safe forensic examination procedures and methodologies during pandemics. The use of narcotic substances was documented as one of the reasons for the increase in the frequency of COVID-19 and the severity of its repercussions.

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    Arab Journal of Forensic Sciences &amp; Forensic Medicine
    Article . 2021 . Peer-reviewed
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      Arab Journal of Forensic Sciences &amp; Forensic Medicine
      Article . 2021 . Peer-reviewed
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    Authors: Rawabi Aljumaiah; Wael Alturaiki; Bandar Alosaimi;

    Besides respiratory symptoms, COVID-19 disease has a wide range of clinical, subclinical, and atypical presentations reported previously. Here, we report the case report of a middle-aged man, with no previous known medical illness, who presented with a 5-day-history of anxiety, fever, confusion, and hallucinations. Patient’s SARS-CoV-2 polymerase chain reaction test was positive, and he underwent daily vital signs and respiratory, cardiovascular, and abdominal examinations. Chest radiography, electrocardiogram, microbial culture, biochemistry, and toxicology tests were also investigated. In this report, a case of COVID-19 is described with an unusual presentation of confusion and hallucinations in the absence of severe upper respiratory or constitutional symptoms. The earlier recognition of atypical manifestation, the safer the practice, with optimal timely diagnosis, and less anticipated outbreaks in healthcare facilities. Further studies are needed to establish the underlying pathophysiological mechanisms involved.

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    Case Reports in Psychiatry
    Article . 2021 . Peer-reviewed
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      Case Reports in Psychiatry
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: ALOTAIBI FAISAL;

    Abstract The epidemic of COVID-19 spread quickly through China and engulfed all of the countries across the globe. Several advances have been made in understanding the novel coronavirus’s pathophysiology and in the development of newer diagnostics with pinpoint accuracy. Several newer therapeutic methods have either been accepted or are awaiting acceptance. In many countries, vaccination programs have been rolled out. Despite all these efforts, coronavirus still exists, though with lesser propensity. Multiple new forms of the novel coronavirus unexpectedly appeared in various areas of the world, undermining previously existing diagnosis and care protocols. This article highlights our understanding of the novel coronavirus’s symptoms in brief, pathogenesis, diagnostics, and therapeutic strategies to contain COVID-19. The clinical findings, including serological, radiological, and other advanced diagnostic strategies, contributed much to control the disease. To date, supportive interventions have been used in tandem with potent antiviral therapies such as remdesivir, lopinavir/ritonavir, or corticosteroids with a level of trust in the care of COVID-19 patients. However, in several areas of the world, vaccination initiatives took place; the vaccines’ safety and efficacy to control the outbreak is yet to be identified. This review concludes that improvement in therapies and diagnostics for COVID-19 must continually be explored as new variants constantly emerge.

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    Acta Pharmaceutica
    Article . 2021 . Peer-reviewed
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    Acta Pharmaceutica
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      Acta Pharmaceutica
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      Acta Pharmaceutica
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  • Authors: Asma Shakoor; Aleeza Sana; Hammad Hassan; Farhan Ahmed; +3 Authors

    Objective: COVID-19 began in Wuhan, China, and has since spread around the world, becoming the leading cause of death in 2020 from the day it infected the first human. The aim of this study was to determine how well the general public knew about COVID-19 and to investigate their attitudes and practices. Methods: This descriptive cross-sectional survey was conducted for the period of two months from July 2021 to August 2021.The sample size was 907. Questionnaire was divided into three components and gathered information about demographic data, knowledge of COVID-19 and their practice section that involves steps taken by the individual to prevent contracting the infection and data was analysed. Results: In this study, 51 %( 463) participants were males and 49 %( 444) were females. 91% of respondents responded that they are aware of the fact that covid-19 is contagious infection. 54% of candidates take preventive measures such as they wash hands frequently, use hand sanitizer, steam inhalation, wear facemasks etc. 50% of respondents are practicing social distance through only going out for essentials for food items, while 16% do social distancing by working from home. Conclusion: The participants indicated a high level of awareness about the COVID-19 pandemic, its outbreak, and basic information about it. Educated people are more likely to believe the scientific facts thus more compliance with preventive measures.The majority of them were satisfied with the actions done by the Government of Punjab. Keywords: Awareness; Attitude; Practices; COVID-19; Public.

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