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11 research outcomes, page 1 of 2
  • publication . Article . 2021
    Open Access English
    Authors:
    Rana Abdelnabi; Caroline S. Foo; Steven De Jonghe; Piet Maes; Birgit Weynand; Johan Neyts;
    Persistent Identifiers
    Publisher: OXFORD UNIV PRESS INC
    Country: Belgium
    Project: EC | SCORE (101003627)

    The emergence of SARS-CoV-2 variants of concern (VoCs) has exacerbated the COVID-19 pandemic. Currently available monoclonal antibodies and vaccines appear to have reduced efficacy against some of these VoCs. Antivirals targeting conserved proteins of SARS-CoV-2 are unl...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Stéphane Pelleau; Tom Woudenberg; Jason Rosado; Françoise Donnadieu; Laura Garcia; Thomas Obadia; Soazic Gardais; Yasmine Elgharbawy; Aurélie Velay; María González; ...
    Persistent Identifiers
    Publisher: Oxford University Press
    Project: EC | MultiSeroSurv (852373), ANR | HuMABK (ANR-18-CE17-0028), EC | SynarchiC (771813)

    Abstract Background Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a complex antibody response that varies by orders of magnitude between individuals and over time. Methods We developed a multiplex serological test for measuring anti...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Bart L. Haagmans; Danny Noack; Nisreen M.A. Okba; Wentao Li; Chunyan Wang; Theo M. Bestebroer; Rory D. de Vries; Sander Herfst; Dennis de Meulder; Elwin Verveer; ...
    Persistent Identifiers
    Publisher: Oxford University Press
    Project: EC | VEO (874735), EC | MANCO (101003651)

    Abstract Effective clinical intervention strategies for coronavirus disease 2019 (COVID-19) are urgently needed. Although several clinical trials have evaluated use of convalescent plasma containing virus-neutralizing antibodies, levels of neutralizing antibodies are us...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Schuit, Michael; Biryukov, Jennifer; Beck, Katie; Yolitz, Jason; Bohannon, Jordan; Weaver, Wade; Miller, David; Holland, Brian; Krause, Melissa; Freeburger, Denise; ...
    Persistent Identifiers
    Publisher: Oxford University Press
    Project: EC | EVA-GLOBAL (871029)

    Abstract Background Our laboratory previously examined the influence of environmental conditions on the stability of an early isolate of SARS-CoV-2 (hCoV-19/USA/WA-1/2020) in aerosols generated from culture medium or simulated saliva. However, genetic differences have e...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Nico A F Janssen; Inge Grondman; Aline H. de Nooijer; Collins K. Boahen; Valerie A. C. M. Koeken; Vasiliki Matzaraki; Vinod Kumar; Xuehui He; Matthijs Kox; Hans J. P. M. Koenen; ...
    Publisher: Oxford University Press (OUP)
    Country: Netherlands
    Project: EC | TRAIN-OLD (833247)

    Abstract The clinical spectrum of COVID-19 varies and the differences in host response characterizing this variation have not been fully elucidated. COVID-19 disease severity correlates with an excessive proinflammatory immune response and profound lymphopenia. Inflamma...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Trieu, Mai-Chi; Bansal, Amit; Madsen, Anders; Zhou, Fan; Sævik, Marianne; Vahokoski, Juha; Brokstad, Karl Albert; Krammer, Florian; Tøndel, Camilla; Mohn, Kristin G I; ...
    Persistent Identifiers
    Publisher: Oxford University Press
    Country: Norway
    Project: EC | INCENTIVE (874866)

    Abstract Background During the coronavirus disease 2019 (COVID-19) pandemic, many countries experienced infection in health care workers (HCW) due to overburdened health care systems. Whether infected HCW acquire protective immunity against severe acute respiratory synd...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Toni Luise Meister; Yannick Brüggemann; Daniel Todt; Carina Conzelmann; Janis A. Müller; Rüdiger Groß; Jan Münch; Adalbert Krawczyk; Jörg Steinmann; Jochen Steinmann; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: EC | Fight-nCoV (101003555)

    The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic creates a significant threat to global health. Recent studies suggested the significance of throat and salivary glands as major sites of virus replication and transmission during early cor...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Toni Luise Meister; Yannick Brüggemann; Daniel Todt; Carina Conzelmann; Janis A Müller; Rüdiger Groß; Jan Münch; Adalbert Krawczyk; Jörg Steinmann; Jochen Steinmann; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: EC | Fight-nCoV (101003555)

    Abstract The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic creates a significant threat to global health. Recent studies suggested the significance of throat and salivary glands as major sites of virus replication and transmission during ...

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  • publication . Article . 2014
    Open Access English
    Authors:
    Stefanie Gierer; Marcel A. Müller; Adeline Heurich; Daniel Ritz; Benjamin L. Springstein; Christina B. Karsten; Alexander Schendzielorz; Kerstin Gnirß; Christian Drosten; Stefan Pöhlmann;
    Persistent Identifiers
    Publisher: Oxford University Press
    Project: EC | EMPERIE (223498)

    Abstract Middle East respiratory syndrome coronavirus (MERS-CoV) infection is associated with a high case-fatality rate, and the potential pandemic spread of the virus is a public health concern. The spike protein of MERS-CoV (MERS-S) facilitates viral entry into host c...

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  • publication . Article . 2014
    Open Access English
    Authors:
    Memish, Ziad A.; Al-Tawfiq, Jaffar A.; Makhdoom, Hatem Q.; Assiri, Abdullah; Alhakeem, Raafat F.; Albarrak, Ali; Alsubaie, Sarah; Al-Rabeeah, Abdullah A.; Hajomar, Waleed H.; Hussain, Raheela; ...
    Persistent Identifiers
    Project: EC | ANTIGONE (278976), EC | EMPERIE (223498), WT

    Abstract Background. Analysis of clinical samples from patients with new viral infections is critical to confirm the diagnosis, to specify the viral load, and to sequence data necessary for characterizing the viral kinetics, transmission, and evolution. We analyzed samp...

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11 research outcomes, page 1 of 2