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864 research outcomes, page 1 of 87
  • publication . Conference object . Preprint . 2021
    Open Access English
    Authors:
    Esteban A. Hernandez-Vargas; César Parra-Rojas; Sorin Olaru;
    Publisher: HAL CCSD
    Country: France

    AbstractAntimicrobial resistance is a major threat to global health and food security today. Scheduling cycling therapies by targeting phenotypic states associated to specific mutations can help us to eradicate pathogenic variants in chronic infections. In this paper, w...

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  • publication . Preprint . Article . 2021
    Open Access English
    Authors:
    Evans K Lodge; Annakate M. Schatz; John M. Drake;
    Publisher: Cold Spring Harbor Laboratory
    Project: NIH | Forecasting tipping point... (1U01GM110744-01), NSF | REU Site: Population Biol... (1156707)

    Abstract Background During outbreaks of emerging and re-emerging infections, the lack of effective drugs and vaccines increases reliance on non-pharmacologic public health interventions and behavior change to limit human-to-human transmission. Interventions that increas...

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  • publication . Article . Preprint . Other literature type . 2021
    Open Access English
    Authors:
    di Gioacchino, Andrea; Šulc, Petr; Komarova, Anastassia V.; Greenbaum, Benjamin D.; Monasson, Rémi; Cocco, Simona;
    Publisher: HAL CCSD
    Country: France
    Project: NIH | Modulating anti-HIV immun... (7R01AI081848-04)

    SARS-CoV-2 infection can lead to acute respiratory syndrome in patients, which can be due in part to dysregulated immune signalling. We analyze here the occurrences of CpG dinucleotides, which are putative pathogen-associated molecular patterns, along the viral sequence...

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Rishikesh Magar; Prakarsh Yadav; Amir Barati Farimani;
    Publisher: Nature Portfolio

    The fast and untraceable virus mutations take lives of thousands of people before the immune system can produce the inhibitory antibody. Recent outbreak of novel coronavirus infected and killed thousands of people in the world. Rapid methods in finding peptides or antib...

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  • publication . Other literature type . Article . Preprint . 2021
    Open Access English
    Authors:
    Bartoszewicz, Jakub M; Seidel, Anja; Renard, Bernhard Y;
    Country: Germany

    Abstract Viruses evolve extremely quickly, so reliable methods for viral host prediction are necessary to safeguard biosecurity and biosafety alike. Novel human-infecting viruses are difficult to detect with standard bioinformatics workflows. Here, we predict whether a ...

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  • publication . Other literature type . Article . Preprint . 2021
    Open Access English
    Authors:
    Georg Hahn; Sanghun Lee; Scott T. Weiss; Christoph Lange;
    Project: NIH | Genetic Epidemiology of C... (5U01HL089897-02), NIH | Genetic Epidemiology of C... (1U01HL089856-01A1), NIH | Integrative & Systems... (5P01HL120839-02), NIH | Preparing Association Ana... (5R01HG008976-03)

    AbstractOver 10,000 viral genome sequences of the SARS-CoV-2 virus have been made readily available during the ongoing coronavirus pandemic since the initial genome sequence of the virus was released on the open access Virological website (http://virological.org/) early...

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  • publication . Article . Other literature type . Preprint . 2021
    Open Access
    Authors:
    Colavizza, Gi.; Costas Comesana, R.; Traag, V.A.; Eck, N.J.P. van; Leeuwen, T.N. van; Waltman, L.R.; Sugimoto Cassidy R;
    Publisher: Public Library of Science (PLoS)
    Country: Netherlands

    AbstractAs the COVID-19 pandemic unfolds, researchers from all disciplines are coming together and contributing their expertise. CORD-19, a dataset of COVID-19 and coronavirus publications, has been made available along-side calls to help mine the information it contain...

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  • publication . Article . Preprint . 2020
    Open Access English
    Authors:
    Shuai He; Lin He Wang; Yang Liu; Yi Qi Li; Hai Tian Chen; Jing Hong Xu; Wan Peng; Guo Wang Lin; Pan Pan Wei; Bo Li; ...
    Publisher: BMC

    Abstract Background As core units of organ tissues, cells of various types play their harmonious rhythms to maintain the homeostasis of the human body. It is essential to identify the characteristics of cells in human organs and their regulatory networks for understandi...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Joffrin, Léa; Goodman, Steve M; Wilkinson, David A; Ramasindrazana, Beza; Lagadec, Erwan; Gomard, Yann; Le Minter, Gildas; Dos Santos, Andrea; Schoeman, M Corrie; Sookhareea, Rajendrapasad; ...
    Publisher: HAL CCSD
    Country: France
    Project: EC | RUN-EMERGE (263958)

    AbstractBats provide key ecosystem services such as crop pest regulation, pollination, seed dispersal, and soil fertilization. Bats are also major hosts for biological agents responsible for zoonoses, such as coronaviruses (CoVs). The islands of the Western Indian Ocean...

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  • publication . Article . Preprint . 2020
    Open Access English
    Authors:
    Fedaa Ali; Menattallah Elserafy; Mohamed H. Alkordi; Muhamed Amin;
    Publisher: Elsevier BV
    Country: Netherlands

    The susceptibility of different populations to SARS-CoV-2 infection is not yet understood. Here, we combined ACE2 coding variants analysis in different populations and computational chemistry calculations to probe the effects on SARS-CoV-2/ACE2 interaction. ACE2-K26R; w...

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864 research outcomes, page 1 of 87