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1,187 research outcomes, page 1 of 119
  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Christophe Batéjat; Quentin Grassin; Jean-Claude Manuguerra; India Leclercq;
    Publisher: KeAi Communications Co., Ltd.

    <jats:title>Abstract</jats:title><jats:p>Supernatants of cells infected with SARS-CoV-2, nasopharyngeal and sera samples containing SARS-CoV-2 were submitted to heat inactivation for various periods of time, ranging from 30 seconds to 60 minutes. Our results showed that...

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Niina Haiminen; Filippo Utro; Edward E. Seabolt; Laxmi Parida;
    Publisher: Nature Publishing Group

    Abstract In response to the ongoing global pandemic, characterizing the molecular-level host interactions of the new coronavirus SARS-CoV-2 responsible for COVID-19 has been at the center of unprecedented scientific focus. However, when the virus enters the body it also...

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Rishikesh Magar; Prakarsh Yadav; Amir Barati Farimani;
    Publisher: Nature Publishing Group UK

    Comment: We have computationally predicted the neutralizing candidates against COVID -19 using machine learning techniques. The main paper is 25 pages(4 figures) and Supporting information is 10 pages(5 figures)

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Yong Zhang; Wanjun Zhao; Yonghong Mao; Yaohui Chen; Shisheng Wang; Yi Zhong; Tao Su; Meng Gong; Dan Du; Xiaofeng Lu; ...
    Publisher: THE AUTHORS. Published by Elsevier Inc on behalf of American Society for Biochemistry and Molecular Biology.

    Graphical abstract

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  • publication . Other literature type . Article . Preprint . 2021
    Open Access
    Authors:
    Jakub M. Bartoszewicz; Anja Seidel; Bernhard Y. Renard;
    Publisher: bioRxiv

    <jats:title>ABSTRACT</jats:title><jats:p>Viruses evolve extremely quickly, so reliable methods for viral host prediction are necessary to safeguard biosecurity and biosafety alike. Novel human-infecting viruses are difficult to detect with standard bioinformatics workfl...

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Shengsheng Lu; Xiaoyan Pan; Daiwei Chen; Xi Xie; Yan Wu; Weijuan Shang; Xiaming Jiang; Yuan Sun; Sheng Fan; Jian He;
    Publisher: Elsevier Inc.

    Graphical abstract

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    S. Kaur; Josué Gómez-Blanco; Ahmad Abdelzaher Zaki Khalifa; S. Adinarayanan; Rubén J. Sánchez-García; Daniel Wrapp; Jason S. McLellan; Khanh Huy Bui; Javier Vargas;
    Publisher: BioRxiv
    Project: NSERC

    Cryo-electron microscopy (cryo-EM) maps usually show heterogeneous distributions of B-factors and electron density occupancies and are typically B-factor sharpened to improve their contrast and interpretability at high-resolutions. However, ‘over-sharpening’ due to the ...

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  • publication . Article . Preprint . 2021
    Open Access
    Authors:
    Jennifer N. Rauch; Eric Valois; Sabrina C. Solley; Friederike Braig; Ryan S. Lach; Morgane Audouard; Jose Carlos Ponce-Rojas; Michael S. Costello; Naomi J. Baxter; Kenneth S. Kosik; ...
    Publisher: eScholarship, University of California

    <jats:title>Abstract</jats:title><jats:p>The COVID-19 pandemic has created massive demand for widespread, distributed tools for detecting SARS-CoV-2 genetic material. The hurdles to scalable testing include reagent and instrument accessibility, availability of highly-tr...

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  • publication . Article . Preprint . Other literature type . 2021
    Open Access English
    Authors:
    Alejandro Lopez-Rincon; Alberto Tonda; Lucero Mendoza-Maldonado; Daphne G.J.C. Mulders; Richard Molenkamp; Carmina A. Perez-Romero; Eric Claassen; Johan Garssen; Aletta D. Kraneveld;

    <jats:title>ABSTRACT</jats:title><jats:p>In this paper, deep learning is coupled with explainable artificial intelligence techniques for the discovery of representative genomic sequences in SARS-CoV-2. A convolutional neural network classifier is first trained on 553 se...

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  • publication . Preprint . Article . 2021
    Open Access English
    Authors:
    Erney Ramírez-Aportela; David Maluenda; Yunior C. Fonseca; Pablo Conesa; Roberto Marabini; J. Bernard Heymann; José María Carazo; Carlos Oscar S. Sorzano;
    Project: EC | INSTRUCT-ULTRA (731005), EC | CORBEL (654248), EC | HighResCells (810057), EC | EOSC-Life (824087)

    Here, the authors present a cryo-EM validation method for the local analysis of the map-to-model fit and introduce FSC-Q as a quality measure. FSC-Q provides a quantitative estimation of how much of the model is supported by the signal content of the map.

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1,187 research outcomes, page 1 of 119