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The following results are related to COVID-19. Are you interested to view more results? Visit OpenAIRE - Explore.
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20 research outcomes, page 1 of 2
  • publication . Article . 2020
    Open Access English
    Authors:
    Paul Bastard; Lindsey B. Rosen; Qian Zhang; Eleftherios Michailidis; Hans-Heinrich Hoffmann; Yu Zhang; Karim Dorgham; Quentin Philippot; Jérémie Rosain; Vivien Béziat; ...
    Publisher: HAL CCSD
    Project: ANR | IFN-COVID19 (ANR-20-COVI-0064), NIH | Developing, Demonstrating... (5UL1TR001866-03), NIH | NHGRI Genome Sequencing P... (5U24HG008956-02), NIH | Inborn errors of immunity... (5R01AI088364-07), NIH | Yale Center for Mendelian... (5UM1HG006504-07), NIH | Modulation of Human Dendr... (5U19AI111825-02), NIH | Type I interferon-stimula... (5R01AI091707-05)

    In a large immunological and genomics study of COVID-19 patients, autoantibodies to type 1 interferons correlated with outcomes.

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  • publication . Article . 2020
    Open Access English
    Authors:
    Alm, Erik; Broberg, Eeva K; Connor, Thomas; Hodcroft, Emma B; Komissarov, Andrey B; Maurer-Stroh, Sebastian; Melidou, Angeliki; Neher, Richard A; O’Toole, Áine; Pereyaslov, Dmitriy; ...
    Publisher: European Centre for Disease Prevention and Control

    We show the distribution of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) genetic clades over time and between countries and outline potential genomic surveillance objectives. We applied three genomic nomenclature systems to all sequence data from the Wor...

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  • publication . Preprint . Conference object . Other literature type . 2020
    Open Access English
    Authors:
    Shang, Xuedong; De Heide, Rianne; Kaufmann, Emilie; Ménard, Pierre; Valko, Michal;
    Project: ANR | BADASS (ANR-16-CE40-0002)

    Due to COVID-19, the event has been postponed. AISTATS 2020 held online on August 26-28th.; International audience; We investigate and provide new insights on the sampling rule called Top-Two Thompson Sampling (TTTS). In particular, we justify its use for fixed-confiden...

  • publication . Article . 2020
    Open Access English
    Authors:
    Alexander E. Gorbalenya; Mart Krupovic; Arcady Mushegian; Andrew M. Kropinski; Stuart G. Siddell; Arvind Varsani; Michael J. Adams; Andrew J. Davison; Bas E. Dutilh; Balázs Harrach; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: UKRI | Persistent Infections (MC_UU_12014/3), EC | EVAg (653316)

    Here, the International Committee on Taxonomy of Viruses describe a new, expanded virus classification scheme with 15 ranks that closely aligns with the Linnaean taxonomic system and better encompasses viral diversity.

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  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Park, Young-Jun; Walls, Alexandra C.; Wang, Zhaoqian; Sauer, Maximillian M.; Li, Wentao; Tortorici, M. Alejandra; Bosch, Berend-Jan; DiMaio, Frank; Veesler, David;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: NIH | Structural Studies of Cor... (5R01GM120553-03)

    The Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe and often lethal respiratory illness in humans, and no vaccines or specific treatments are available. Infections are initiated via binding of the MERS-CoV spike (S) glycoprotein to sialosides and ...

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  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Ogando, N.S.; Ferron, F.; Decroly, E.; Canard, B.; Posthuma, C.C.; Snijder, E.J.;
    Project: NWO | Viral RNA polymerases: th... (2300162767), EC | ANTIVIRALS (642434)

    International audience; Among RNA viruses, the order Nidovirales stands out for including viruses with the largest RNA genomes currently known. Nidoviruses employ a complex RNA-synthesizing machinery comprising a variety of non-structural proteins (nsps). One of the pos...

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  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Tortorici, M. Alejandra; Walls, Alexandra C.; Lang, Yifei; Wang, Chunyan; Li, Zeshi; Koerhuis, Danielle; Boons, Geert-Jan; Bosch, Berend-Jan; Rey, Félix A.; de Groot, Raoul J.; ...
    Persistent Identifiers
    Project: NIH | Direct Detection Device f... (1S10OD018111-01), NIH | Structural Studies of Cor... (5R01GM120553-03), NSF | MRI: Acquisition of a dir... (1338135), NIH | West/Midwest Consortium f... (5U24GM116792-03), NIH | High-End CryoEM Instrumen... (1S10RR023057-01)

    International audience; Coronaviruses cause respiratory tract infections in humans and outbreaks of deadly pneumonia worldwide. Infections are initiated by the transmembrane spike (S) glycoprotein, which binds to host receptors and fuses the viral and cellular membranes...

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  • publication . Other literature type . Article . 2019
    Open Access
    Authors:
    Walls, Alexandra C.; Xiong, Xiaoli; Park, Young Jun; Tortorici, M. Alejandra; Snijder, Joost; Quispe, Joel; Cameroni, Elisabetta; Gopal, Robin; Dai, Mian; Lanzavecchia, Antonio; ...
    Publisher: Elsevier BV
    Project: NIH | Structural Studies of Cor... (5R01GM120553-03)

    Recent outbreaks of severe acute respiratory syndrome and Middle East respiratory syndrome, along with the threat of a future coronavirus-mediated pandemic, underscore the importance of finding ways to combat these viruses. The trimeric spike transmembrane glycoprotein ...

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  • publication . Other literature type . Article . 2017
    Open Access
    Authors:
    Xiong, Xiaoli; Tortorici, M Alejandra; Snijder, Joost; Yoshioka, Craig; Walls, Alexandra C; Li, Wentao; McGuire, Andrew T; Rey, Félix A; Bosch, Berend-Jan; Veesler, David;
    Persistent Identifiers

    <jats:p>Coronaviruses recently emerged as major human pathogens causing outbreaks of severe acute respiratory syndrome and Middle-East respiratory syndrome. They utilize the spike (S) glycoprotein anchored in the viral envelope to mediate host attachment and fusion of t...

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  • publication . Other literature type . Article . 2017
    Open Access
    Authors:
    Walls, Alexandra; Tortorici, M. Alejandra; Snijder, Joost; Xiong, Xiaoli; Bosch, Berend-Jan; Rey, Félix A.; Veesler, David;
    Persistent Identifiers
    Publisher: Proceedings of the National Academy of Sciences

    International audience; The tremendous pandemic potential of coronaviruses was demonstrated twice in the past few decades by two global outbreaks of deadly pneumonia. The coronavirus spike (S) glycoprotein initiates infection by promoting fusion of the viral and cellula...

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20 research outcomes, page 1 of 2