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36 research outcomes, page 1 of 4
  • publication . Article . 2016
    Open Access
    Authors:
    Amanda Rojek; Peter Horby;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC
    Project: WT | International Severe Acut... (107834), UKRI | International Severe Acut... (MC_PC_15001), WT | Emergency Evaluation of T... (106491), EC | PREPARE (602525), NHMRC | Viral caspase inhibitors (602525)

    Background<br> Emerging and epidemic infectious disease outbreaks are a significant public health problem and global health security threat. As an outbreak begins, epidemiological investigations and traditional public health responses are generally mounted very quickly....

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  • publication . Article . 2016
    Open Access English
    Authors:
    Bioglio L; Génois M; Cl, Vestergaard; Poletto C; Barrat A; Vittoria Colizza;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | PREDEMICS (278433), ANR | HarMS-flu (ANR-12-MONU-0018), ANR | Amidex (ANR-11-IDEX-0001), EC | MULTIPLEX (317532)

    Background The homogeneous mixing assumption is widely adopted in epidemic modelling for its parsimony and represents the building block of more complex approaches, including very detailed agent-based models. The latter assume homogeneous mixing within schools, workplac...

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  • publication . Article . 2016
    Open Access English
    Authors:
    Min, Jae; Cella, Eleonora; Ciccozzi, Massimo; Pelosi, Antonello; Salemi, Marco; Prosperi, Mattia;
    Persistent Identifiers
    Publisher: BioMed Central
    Project: EC | VIROGENESIS (634650)

    Background Since its discovery in 2012, over 1700 confirmed cases of Middle East Respiratory Syndrome (MERS) have been documented worldwide and more than a third of those cases have died. While the greatest number of cases has occurred in Saudi Arabia, the recent export...

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  • publication . Article . 2016
    Open Access English
    Authors:
    Rafael Sanjuán; Pilar Domingo-Calap;
    Persistent Identifiers
    Publisher: Springer International Publishing
    Project: EC | VIRMUT (281191)

    The remarkable capacity of some viruses to adapt to new hosts and environments is highly dependent on their ability to generate de novo diversity in a short period of time. Rates of spontaneous mutation vary amply among viruses. RNA viruses mutate faster than DNA viruse...

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  • publication . Article . 2016
    Open Access
    Authors:
    Cheng Xu; Øystein Evensen; Hetron Mweemba Munang’andu;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC
    Project: EC | TARGETFISH (311993)

    Background The Janus kinase (Jak) and signaling transducer activator of transcription (Stat) pathway mediates the signaling of genes required for cellular development and homeostasis. To elucidate the effect of type I IFN on the Jak/stat pathway in salmonid alphavirus s...

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  • publication . Article . 2016
    Open Access
    Authors:
    Melanie Eck; Margarita García Durán; Meret E. Ricklin; Samira Locher; Javier Sarraseca; María José Rodríguez; Kenneth C. McCullough; Artur Summerfield; Gert Zimmer; Nicolas Ruggli;
    Persistent Identifiers
    Project: EC | PORRSCON (245141)

    International audience; AbstractPorcine reproductive and respiratory syndrome virus (PRRSV) is the causative agent of one of the most devastating and economically significant viral disease of pigs worldwide. The vaccines currently available on the market elicit only lim...

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  • publication . Article . 2016
    Open Access
    Authors:
    Dellicour, Simon; Rose, Rebecca; Pybus, Oliver G.;
    Persistent Identifiers
    Publisher: Springer Nature
    Project: EC | PATHPHYLODYN (614725)

    info:eu-repo/semantics/published

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  • publication . Article . 2016
    Open Access English
    Authors:
    Edin Hamzic; Rikke B. Kjærup; Núria Mach; Guilietta Minozzi; Francesco Strozzi; Valentina Gualdi; John L. Williams; Jun Chen; Eva Wattrang; Bart Buitenhuis; ...
    Persistent Identifiers
    Publisher: BioMed Central
    Project: EC | NADIR (228394)

    Background Avian infectious bronchitis is a highly contagious disease of the upper-respiratory tract caused by infectious bronchitis virus (IBV). Understanding the molecular mechanisms involved in the interaction between innate and adaptive immune responses to IBV infec...

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  • publication . Article . 2015
    Open Access English
    Authors:
    García-Nicolás, Obdulio; Rosales, Rubén S; Pallarés, Francisco J; Risco, David; Quereda, Juan J; Graham, Simon P; Frossard, Jean-Pierre; Morgan, Sophie B; Steinbach, Falko; Drew, Trevor W; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | PORRSCON (245141), EC | NADIR (228394)

    El virus del síndrome reproductivo y respiratorio porcino (PRRSV) induce una respuesta inmune débil, permitiendo su persistencia en diferentes órganos de cerdos infectados. Esto se ha atribuido a la habilidad de PRRSV para influir en las respuestas inducidas por las cit...

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  • publication . Article . 2015
    Open Access English
    Authors:
    Chiara Poletto; Pierre-Yves Boëlle; Vittoria Colizza;
    Persistent Identifiers
    Publisher: Springer Nature
    Project: EC | PREDEMICS (278433), ANR | HarMS-flu (ANR-12-MONU-0018)

    Background The continuing circulation of MERS in the Middle East makes the international dissemination of the disease a permanent threat. To inform risk assessment, we investigated the spatiotemporal pattern of MERS global dissemination and looked for factors explaining...

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36 research outcomes, page 1 of 4