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7 research outcomes, page 1 of 1
  • Background Inosine pranobex (Isoprinosine®) is an immunomodulatory drug approved in several countries for the treatment of viral infections. This study compared the efficacy and safety of inosine pranobex versus placebo in subjects with clinically diagnosed influenza-li...

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  • publication . Article . 2016
    Open Access
    Authors:
    Martin Plasil; Elmira Mohandesan; Robert R. Fitak; Petra Musilova; Svatava Kubickova; Pamela A. Burger; Petr Horin;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC
    Project: FWF | Genomic signatures of dom... (P 24706)

    Background The Major Histocompatibility Complex (MHC) is a genomic region containing genes with crucial roles in immune responses. MHC class I and class II genes encode antigen-presenting molecules expressed on the cell surface. To counteract the high variability of pat...

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  • publication . Article . 2015
    Open Access
    Authors:
    Libuše Turjanicová; Libor Mikeš; Monika Peckova; Petr Horák;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC

    Background The nasal avian schistosome Trichobilharzia regenti spends part of its intravertebrate period of life within the central nervous system. Migration of the parasites can be accompanied by neuromotor disorders or paralysis in natural definitive hosts (ducks) and...

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  • publication . Article . 2014
    Open Access English
    Authors:
    Baldwin, Heather J; Vallo, Peter; Gardner, Michael G; Drosten, Christian; Tschapka, Marco; Stow, Adam J;
    Persistent Identifiers

    Background Noack’s leaf-nosed bat, Hipposideros ruber, is a cryptic species within the Hipposideros caffer species complex. Despite a widespread distribution in Africa and being host to potentially zoonotic viruses, the genetic structure and ecology of H. ruber is poorl...

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  • publication . Article . 2013
    Open Access English
    Authors:
    Martin Palus; Jarmila Vojtíšková; Jiří Salát; Jan Kopecký; Libor Grubhoffer; Marie Lipoldová; Peter Demant; Daniel Růžek;
    Persistent Identifiers
    Publisher: BioMed Central

    Background The clinical course of tick-borne encephalitis (TBE), a disease caused by TBE virus, ranges from asymptomatic or mild influenza-like infection to severe debilitating encephalitis or encephalomyelitis. Despite the medical importance of this disease, some cruci...

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  • publication . Article . 2012
    Open Access English
    Authors:
    Stein, Mart Lambertus; Rudge, James W; Coker, Richard; van der Weijden, Charlie; Krumkamp, Ralf; Hanvoravongchai, Piya; Chavez, Irwin; Putthasri, Weerasak; Phommasack, Bounlay; Adisasmito, Wiku; ...
    Persistent Identifiers
    Publisher: BIOMED CENTRAL LTD
    Project: EC | ASIAFLUCAP (201823)

    <p>Abstract</p> <p>Background</p> <p>Health care planning for pandemic influenza is a challenging task which requires predictive models by which the impact of different response strategies can be evaluated. However, current preparedness plans and simulations exercises, ...

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  • publication . Article . 2008
    Open Access
    Authors:
    Matějková, Petra; Strouhal, Michal; Šmajs, David; Norris, Steven J; Palzkill, Timothy; Petrosino, Joseph F; Sodergren, Erica; Norton, Jason E; Singh, Jaz; Richmond, Todd A; ...
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC
    Project: NIH | GENETIC ORGANIZATION OF T... (5R01DE012488-02), NIH | MICROBIAL GENOMICS (5R01DE013759-02), NIH | Physiologic Characteristi... (5R01AI049252-03)

    Background Syphilis spirochete Treponema pallidum ssp. pallidum remains the enigmatic pathogen, since no virulence factors have been identified and the pathogenesis of the disease is poorly understood. Increasing rates of new syphilis cases per year have been observed r...

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7 research outcomes, page 1 of 1