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2 research outcomes, page 1 of 1
  • publication . Article . Other literature type . 2017
    Open Access
    Authors:
    Kathrin Pieper; Joshua Tan; Luca Piccoli; Mathilde Foglierini; Sonia Barbieri; Yiwei Chen; Chiara Silacci-Fregni; Tobias Wolf; David Jarrossay; Marica Anderle; ...
    Publisher: Springer Science and Business Media LLC
    Project: EC | BROADimmune (670955), WT

    In two previously described donors, the extracellular domain of LAIR1, a collagen-binding inhibitory receptor encoded on chromosome 19 (ref. 1), was inserted between the V and DJ segments of an antibody. This insertion generated, through somatic mutations, broadly react...

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  • publication . Article . 2015
    Open Access
    Authors:
    Tan, Joshua; Pieper, Kathrin; Piccoli, Luca; Abdi, Abdirahman; Foglierini, Mathilde; Geiger, Roger; Maria Tully, Claire; Jarrossay, David; Maina Ndungu, Francis; Wambua, Juliana; ...
    Persistent Identifiers
    Project: WT | Developing research capac... (084538), SNSF | Human B cells and plasma ... (310030_141254), EC | BROADimmune (670955), SNSF | Analytic vaccinology (310030B_160279), WT | Director's discretionary ... (077092), WT | Immunology, Infection & T... (099811), WT | Measuring the impact of n... (084535), WT | Integrated studies of the... (092741), WT | Non-var-Encoded Variant A... (084378), EC | IMMUNEXPLORE (250348),...

    None: Plasmodium falciparum antigens expressed on the surface of infected erythrocytes are important targets of naturally acquired immunity against malaria, but their high number and variability provide the pathogen with a powerful means of escape from host antibodies. ...

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2 research outcomes, page 1 of 1