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The following results are related to COVID-19. Are you interested to view more results? Visit OpenAIRE - Explore.
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8 research outcomes, page 1 of 1
  • publication . Article . 2020
    Open Access English
    Authors:
    Litviňuková, Monika; Talavera-López, Carlos; Maatz, Henrike; Reichart, Daniel; Worth, Catherine L.; Lindberg, Eric L.; Kanda, Masatoshi; Polanski, Krzysztof; Heinig, Matthias; Lee, Michael; ...
    Publisher: Nature
    Project: EC | CodingHeart (788970)

    Single-cell and single-nucleus RNA sequencing are used to construct a cellular atlas of the human heart that will aid further research into cardiac physiology and disease.

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  • publication . Article . 2020
    Open Access English
    Authors:
    Shin, Donghyuk; Mukherjee, Rukmini; Grewe, Diana; Bojkova, Denisa; Baek, Kheewoong; Bhattacharya, Anshu; Schulz, Laura; Widera, Marek; Mehdipour, Ahmad Reza; Tascher, Georg; ...
    Project: EC | Nedd8Activate (789016)

    Biochemical, structural and functional studies on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) papain-like protease PLpro reveal that it regulates host antiviral responses by preferentially cleaving the ubiquitin-like interferon-stimulated gene 15 pr...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Denisa Bojkova; Kevin Klann; Benjamin Koch; Marek Widera; David Krause; Sandra Ciesek; Jindrich Cinatl; Christian Münch;
    Persistent Identifiers
    Project: EC | mitoUPR (803565)

    A new coronavirus was recently discovered and named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Infection with SARS-CoV-2 in humans causes coronavirus disease 2019 (COVID-19) and has been rapidly spreading around the globe1,2. SARS-CoV-2 shows some sim...

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  • publication . Preprint . Article . Other literature type . 2020
    Open Access English
    Authors:
    Hauke S. Hillen; Goran Kokic; Lucas Farnung; Christian Dienemann; Dimitry Tegunov; Patrick Cramer;
    Publisher: Cold Spring Harbor Laboratory
    Project: EC | TRANSREGULON (693023)

    The new coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses an RNA-dependent RNA polymerase (RdRp) for the replication of its genome and the transcription of its genes1-3. Here we present a cryo-electron microscopy structure of the SARS-CoV-2 R...

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  • publication . Article . Other literature type . 2007
    Open Access
    Authors:
    Radoshitzky, Sheli R.; Abraham, Jonathan; Spiropoulou, Christina F.; Kuhn, Jens H.; Nguyen, Dan; Li, Wenhui; Nagel, Jane; Schmidt, Paul J.; Nunberg, Jack H.; Andrews, Nancy C.; ...
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC

    The transferrin receptor 1 (TfR1) has been identified as the cellular receptor for four New World arenaviruses — the Junin, Machupo, Guanarito and Sabia viruses. This class of arenaviruses is important because they cause fatal haemorrhagic fevers. Treating cultured cell...

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  • publication . Article . Other literature type . 2005
    Open Access English
    Authors:
    Imai, Yumiko; Kuba, Keiji; Rao, Shuan; Huan, Yi; Guo, Feng; Guan, Bin; Yang, Peng; Sarao, Renu; Wada, Teiji; Leong-Poi, Howard; ...
    Persistent Identifiers
    Publisher: Nature Publishing Group UK
    Project: CIHR

    Acute respiratory distress syndrome (ARDS), the most severe form of acute lung injury, is a devastating clinical syndrome with a high mortality rate (30–60%) (refs 1–3). Predisposing factors for ARDS are diverse1,3 and include sepsis, aspiration, pneumonias and infectio...

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  • publication . Article . 2004
    Open Access English
    Authors:
    R. Watanabe; Helmut Wege; Volker ter Meulen;
    Persistent Identifiers
    Publisher: Nature Publishing Group UK

    Viruses have been found to induce inflammatory demyelinating lesions in central nervous system (CNS) tissue of both animal and man, either by natural infections or after vaccination1,2. At least two different pathogenic mechanisms have been proposed for these changes, a...

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  • publication . Article . 2004
    Open Access
    Authors:
    P T Massa; R. Dörries; V. ter Meulen;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC

    Recent studies have shown that gamma-interferon (IFN-gamma) induces the expression of Ia antigen on astrocytes. This observation is of immunological significance because such activated astrocytes can act as antigen-presenting cells, as demonstrated with myelin basic pro...

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8 research outcomes, page 1 of 1