Quick search
Advanced search in
Research outcomes
Field to searchTerm
Add rule
The following results are related to COVID-19. Are you interested to view more results? Visit OpenAIRE - Explore.
Download Results
9 research outcomes, page 1 of 1
  • publication . Article . 2019
    Open Access English
    Authors:
    Xiaoyu Zhao; Hin Chu; Bosco Ho-Yin Wong; Man Chun Chiu; Dong Wang; Cun Li; Xiaojuan Liu; Dong Yang; Vincent Kwok-Man Poon; Jian-Piao Cai; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    <jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background</jats:title> <jats:p>Human infection with Middle East respiratory syndrome coronavirus (MERS-CoV) poses an ongoing threat to public health worldwide. The studies of MERS patients with severe disease and...

    Add to ORCID
  • publication . Other literature type . Article . 2016
    Open Access
    Authors:
    Chu, Hin; Zhou, Jie; Wong, Bosco Ho-Yin; Li, Cun; Chan, Jasper Fuk-Woo; Cheng, Zhong-Shan; Yang, Dong; Wang, Dong; Lee, Andrew Chak-Yiu; Li, Chuangen; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    Abstract Middle East respiratory syndrome (MERS) is associated with a mortality rate of >35%. We previously showed that MERS coronavirus (MERS-CoV) could infect human macrophages and dendritic cells and induce cytokine dysregulation. Here, we further investigated the in...

    Add to ORCID
  • publication . Article . Other literature type . 2015
    Open Access English
    Authors:
    Chan, Jasper Fuk-Woo; Yao, Yanfeng; Yeung, Man-Lung; Deng, Wei; Bao, Linlin; Jia, Lilong; Li, Fengdi; Xiao, Chong; Gao, Hong; Yu, Pin; ...
    Persistent Identifiers

    Abstract Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe disease in human with an overall case-fatality rate of >35%. Effective antivirals are crucial for improving the clinical outcome of MERS. Although a number of repurposed drugs, convalescent-p...

    Add to ORCID
  • publication . Other literature type . Article . 2013
    Open Access
    Authors:
    Chan, Jasper Fuk-Woo; Chan, Kwok-Hung; Choi, Garnet Kwan-Yue; To, Kelvin Kai-Wang; Tse, Herman; Cai, Jian-Piao; Yeung, Man Lung; Cheng, Vincent Chi-Chung; Chen, Honglin; Che, Xiao-Yan; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    Abstract The emerging novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) was recently isolated from patients with severe pneumonia and renal failure and was associated with an unexplained high crude fatality rate of 56%. We performed a cell line susceptibility study wit...

    Add to ORCID
  • publication . Other literature type . Article . 2011
    Open Access
    Authors:
    Ling, Man To; Tu, Wenwei; Han, Yan; Mao, Huawei; Chong, Wai Po; Guan, Jing; Liu, Ming; Lam, Kwok Tai; Law, Helen K. W.; Peiris, J. S. Malik; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: NIH | Development of novel immu... (1U01AI074503-01)

    Background. Mannose-binding lectin (MBL) is a pattern-recognition molecule, which functions as a first line of host defense. Pandemic H1N1 (pdmH1N1) influenza A virus caused massive infection in 2009 and currently circulates worldwide. Avian influenza A H9N2 (H9N2/G1) v...

    Add to ORCID
  • publication . Article . 2010
    Open Access
    Authors:
    Johannes Chi Yun Ching; Kelvin Y.K. Chan; Eric Hing Leung Lee; Mei Shu Xu; Campbell Kam Po Ting; Thomas Man Kit So; Pak C. Sham; Gabriel M. Leung; Joseph S. M. Peiris; Ui-Soon Khoo;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    Myxovirus resistance A (MxA) is an antiviral protein induced by interferon alpha and beta (IFN-alpha, IFN-beta) that can inhibit viral replication. The minor alleles of the -88G>T and -123C>A MxA promoter single-nucleotide polymorphisms (SNPs) are associated with increa...

    Add to ORCID
  • publication . Article . 2007
    Open Access English
    Authors:
    Susanna K. P. Lau; Cyril C. Y. Yip; Tak-Lun Que; Rodney A. Lee; Rex Au-Yeung; Boping Zhou; Lok-Yee So; Yu-Lung Lau; Kwok-Hung Chan; Patrick C. Y. Woo; ...
    Persistent Identifiers
    Publisher: The University of Chicago Press

    Abstract Background. Human bocavirus (HBoV) is a recently discovered parvovirus associated with respiratory tract infections in children. We conducted the first systematic prospective clinical and molecular study using nasopharyngeal aspirates (NPAs) and fecal samples. ...

    Add to ORCID
  • publication . Other literature type . Article . 2005
    Open Access
    Authors:
    Woo, Patrick C. Y.; Lau, Susanna K. P.; Tsoi, Hoi-wah; Huang, Yi; Poon, Rosana W. S.; Chu, Chung-ming; Lee, Rodney A.; Luk, Wei-kwang; Wong, Gilman K. M.; Wong, Beatrice H. L.; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    Background Recently, we described the discovery of a novel group 2 coronavirus, coronavirus HKU1 (CoV-HKU1), from a patient with pneumonia. However, the clinical and molecular epidemiological features of CoV-HKU1-associated pneumonia are unknown. Methods Prospectively c...

    Add to ORCID
  • publication . Other literature type . Article . 2005
    Open Access
    Authors:
    Che, Xiao-yan; Qiu, Li-wen; Liao, Zhi-yong; Wang, Ya-di; Wen, Kun; Pan, Yu-xian; Hao, Wei; Mei, Ya-bo; Cheng, Vincent C. C.; Yuen, Kwok-yung;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    Abstract Cross-reactivity between antibodies to different human coronaviruses (HCoVs) has not been systematically studied. By use of Western blot analysis, indirect immunofluorescence assay (IFA), and enzyme-linked immunosorbent assay (ELISA), antigenic cross-reactivity...

    Add to ORCID
9 research outcomes, page 1 of 1