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8 research outcomes, page 1 of 1
  • publication . Article . 2018
    Open Access English
    Authors:
    Thoa Thi Than; Eunji Jo; Daniel Todt; Phuong Hong Nguyen; Jochen Steinmann; Eike Steinmann; Marc P. Windisch;
    Persistent Identifiers
    Publisher: Oxford University Press

    Abstract Hepatitis B virus (HBV) infection is considered a major public health problem worldwide, and a significant number of reports on nosocomial and occupational outbreaks have been reported. This systematic investigation of HBV stability and susceptibility to differ...

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  • publication . Other literature type . Article . 2017 . Embargo End Date: 15 Mar 2017
    Open Access English
    Authors:
    Siddharta, Anindya; Pfaender, Stephanie; Vielle, Nathalie Jane; Dijkman, Ronald; Friesland, Martina; Becker, Britta; Yang, Jaewon; Engelmann, Michael; Todt, Daniel; Windisch, Marc P.; ...
    Publisher: Oxford University Press

    Abstract The World Health Organization (WHO) published 2 alcohol-based formulations to be used in healthcare settings and for outbreak-associated infections, but inactivation efficacies of these products have not been determined against (re-)emerging viruses. In this st...

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  • publication . Article . 2015
    Open Access
    Authors:
    Florian Wrensch; Christina B. Karsten; Kerstin Gnirß; Markus Hoffmann; Kai Lu; Ayato Takada; Michael Winkler; Graham Simmons; Stefan Pöhlmann;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: NIH | Broad spectrum antivirals... (1R21AI107165-01)

    Ebolaviruses are highly pathogenic in humans and nonhuman primates and pose a severe threat to public health. The interferon-induced transmembrane (IFITM) proteins can restrict entry of ebolaviruses, influenza A viruses, and other enveloped viruses. However, the breadth...

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  • publication . Article . Other literature type . 2015
    Open Access
    Authors:
    Franziska Dahlmann; Nadine Biedenkopf; Anne Babler; Willi Jahnen-Dechent; Christina B. Karsten; Kerstin Gnirß; Heike Schneider; Florian Wrensch; Christopher A. O’Callaghan; Stephanie Bertram; ...
    Publisher: Oxford University Press (OUP)

    Published by Oxford Univ. Press, Oxford [u.a.]

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  • publication . Article . 2015
    Open Access
    Authors:
    Heike Hofmann-Winkler; Kerstin Gnirß; Florian Wrensch; Stefan Pöhlmann;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    The ongoing Ebola virus (EBOV) disease (EVD) epidemic in Western Africa is the largest EVD outbreak recorded to date and requires the rapid development and deployment of antiviral measures. The viral glycoprotein (GP) facilitates host cell entry and, jointly with cellul...

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  • publication . Article . 2014
    Open Access
    Authors:
    Stefanie Gierer; Marcel A. Müller; Adeline Heurich; Daniel Ritz; Benjamin L. Springstein; Christina B. Karsten; Alexander Schendzielorz; Kerstin Gnirß; Christian Drosten; Stefan Pöhlmann;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: EC | EMPERIE (223498)

    Abstract Middle East respiratory syndrome coronavirus (MERS-CoV) infection is associated with a high case-fatality rate, and the potential pandemic spread of the virus is a public health concern. The spike protein of MERS-CoV (MERS-S) facilitates viral entry into host c...

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  • publication . Article . Other literature type . 2011
    Open Access
    Authors:
    Annika Kühl; Markus Hoffmann; Marcel A. Müller; Vincent J. Munster; Kerstin Gnirß; Miriam Kiene; Theodros Solomon Tsegaye; Georg M. N. Behrens; Georg Herrler; Heinz Feldmann; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: EC | EMPERIE (223498)

    Infection with Ebola virus (EBOV) causes hemorrhagic fever in humans with high case-fatality rates. The EBOV-glycoprotein (EBOV-GP) facilitates viral entry and promotes viral release from human cells. African fruit bats are believed not to develop disease upon EBOV infe...

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  • publication . Article . Other literature type . 2011
    Open Access
    Authors:
    Annika Kühl; Carina Banning; Andrea Marzi; Jörg Votteler; Imke Steffen; Stephanie Bertram; Ilona Glowacka; Andreas Konrad; Michael Stürzl; Ju-Tao Guo; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    The interferon-α (IFNα)–inducible cellular protein tetherin is a novel human immunodeficiency virus (HIV) restriction factor, which inhibits the release of progeny virions from infected cells [1, 2]. The antiviral action of tetherin is counteracted by the HIV-1 accessor...

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8 research outcomes, page 1 of 1