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66 research outcomes, page 1 of 7
  • publication . Article . 2021
    Open Access
    Authors:
    Genay Pilarowski; Paul Lebel; Sara Sunshine; Jamin Liu; Emily D. Crawford; Carina Marquez; Luis Rubio; Gabriel Chamie; Jackie Martinez; James Peng; ...
    Persistent Identifiers
    Publisher: eScholarship, University of California

    <jats:title>Abstract</jats:title> <jats:p>We evaluated the performance of the Abbott BinaxNOW rapid antigen test for coronavirus disease 2019 (Binax-CoV2) to detect virus among persons, regardless of symptoms, at a public plaza site of ongoing community transmission. Ti...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Saki Takahashi; Bryan Greenhouse; Isabel Rodriguez-Barraquer;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    <jats:title>Abstract</jats:title> <jats:p>Biased seroprevalence estimates can occur using serological assays optimized with validation sets unrepresentative of disease spectrum in the general population. Correct interpretation of serosurveys for severe acute respiratory...

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  • publication . Article . Preprint . Other literature type . 2020
    Open Access
    Authors:
    Marta Galanti; Jeffrey Shaman;
    Publisher: Oxford University Press (OUP)

    Abstract Background Although the mechanisms of adaptive immunity to pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are still unknown, the immune response to the widespread endemic coronaviruses HKU1, 229E, NL63, and OC43 provide a useful reference...

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  • publication . Article . Preprint . 2020
    Open Access English
    Authors:
    Waghmare, Alpana; Krantz, Elizabeth M; Baral, Subhasish; Vasquez, Emma; Loeffelholz, Tillie; Chung, E. Lisa; Pandey, Urvashi; Kuypers, Jane; Duke, Elizabeth R; Jerome, Keith R; ...
    Persistent Identifiers
    Publisher: Oxford University Press
    Project: NIH | Viral and Host Biomarkers... (5K23AI114844-02), NIH | Infections in Hematopoiet... (5K24HL093294-08)

    The SARS-CoV-2 pandemic demonstrates the need for accurate and convenient approaches to diagnose and therapeutically monitor respiratory viral infections. We demonstrated that self-sampling with foam swabs is well-tolerated and provides quantitative viral output concord...

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  • publication . Article . Preprint . Other literature type . 2020
    Open Access English
    Authors:
    Bruna G G Pinto; Antonio E R Oliveira; Youvika Singh; Leandro Jimenez; Andre N A Gonçalves; Rodrigo L T Ogava; Rachel Creighton; Jean Pierre Schatzmann Peron; Helder I. Nakaya;
    Publisher: Cold Spring Harbor Laboratory
    Project: NSF | Graduate Research Fellows... (1256082), NIH | STD and AIDS Research Tra... (2T32AI007140-41)

    <jats:title>Abstract</jats:title><jats:p>The pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS- CoV-2) has resulted in several thousand deaths worldwide in just a few months. Patients who died from Coronavirus disease 2019 (COVID-19) often had...

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  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    Michelle L. Pleet; James Erickson; Catherine DeMarino; Robert A. Barclay; Maria Cowen; Benjamin Lepene; Janie Liang; Jens H. Kuhn; Laura I. Prugar; Spencer W. Stonier; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: NIH | A radiation-induced cellu... (1R21AI127351-01), NIH | Probes to target the 3-wa... (5R01AR068436-03), NIH | HIV-1 TAR derived miRNA: ... (7R21AI078859-02), NIH | Effect of chromatin remod... (1R21AI074410-01A1), NIH | HIV neuropathogenesis rel... (5R01NS099029-02), NIH | HIV-1 Inhibition Using Ta... (5R01AI043894-13), NIH | Protein painting identifi... (5R33CA206937-03)

    Background Ebola virus (EBOV) mainly targets myeloid cells; however, extensive death of T cells is often observed in lethal infections. We have previously shown that EBOV VP40 in exosomes causes recipient immune cell death. Methods Using VP40-producing clones, we analyz...

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  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    Jatin M. Vyas; Jayaraj Rajagopal; Caroline L. Sokol; Marc N. Wein; Michael K. Mansour; Kathleen E. Corey; Mark C. Fishman; Katrina Armstrong;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: NIH | The Functional Role of th... (5R01AI136529-02), NIH | Molecular Biology and Gen... (5P30AI060354-10), NIH | The role of TLR9 on Asper... (5R01AI097519-03)

    Residency training is a profound experience that greatly influences the career trajectory of every trainee. Currently, residency programs focus heavily (or almost exclusively) on the acquisition of medical knowledge and fail to foster intellectual curiosity and introduc...

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  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    Liise Anne Pirofski; Arturo Casadevall;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: NIH | B cell subsets and immuni... (6R01AI097096-05), NIH | Effects of aging and HIV ... (5R01AG045044-05), NIH | Biology of Fungal Melanin (5R01AI052733-03), NIH | Protective antibodies for... (5R01AI033774-18), NIH | Synergy of Host Defense M... (2R01HL059842-06), NIH | Molecular Biology and Gen... (5P30AI060354-10), NIH | Molecular Characterizatio... (3R37AI033142-15S1)

    The Damage–Response Framework (DRF) is a powerful tool to inform research in infectious diseases. It can integrate clinical observation with microbiology and immunology to incorporate the role of the host response into the outcome of microbial pathogenesis. Although the...

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  • publication . Article . 2018
    Open Access
    Authors:
    Thomas C. Luke; Richard S. Bennett; Dawn M. Gerhardt; Tracey Burdette; Elena Postnikova; Steven Mazur; Anna N. Honko; Nicholas Oberlander; Russell Byrum; Dan R. Ragland; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    Abstract Transchromosomic bovines (Tc-bovines) adaptively produce fully human polyclonal immunoglobulin (Ig)G antibodies after exposure to immunogenic antigen(s). The National Interagency Confederation for Biological Research and collaborators rapidly produced and then ...

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  • publication . Article . 2018
    Open Access English
    Authors:
    Olena Shtanko; Ann N. Reyes; William T. Jackson; Robert A. Davey;
    Persistent Identifiers
    Publisher: Oxford University Press
    Project: NIH | Receptor Trafficking in E... (5R01AI063513-05)

    Abstract Ebola virus (EBOV) enters host cells by macropinocytosis, a poorly understood process. Recent studies have suggested that cell factors involved in autophagy, an evolutionally conserved pathway leading to the lysosomal degradation of protein aggregates and organ...

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66 research outcomes, page 1 of 7