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The following results are related to COVID-19. Are you interested to view more results? Visit OpenAIRE - Explore.
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7 research outcomes, page 1 of 1
  • publication . Article . 2021
    Open Access English
    Authors:
    Nico A. F. Janssen; Inge Grondman; Aline H. de Nooijer; Collins K Boahen; Valerie A C M Koeken; Vasiliki Matzaraki; Vinod Kumar; Xuehui He; Matthijs Kox; Hans J. P. M. Koenen; ...
    Publisher: Oxford University Press (OUP)
    Project: EC | TRAIN-OLD (833247)

    <jats:title>Abstract</jats:title> <jats:p>The clinical spectrum of COVID-19 varies and the differences in host response characterizing this variation have not been fully elucidated. COVID-19 disease severity correlates with an excessive proinflammatory immune response a...

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  • publication . Article . 2020
    Open Access English
    Authors:
    de Nooijer, Aline H; Grondman, Inge; Janssen, Nico A F; Netea, Mihai G; Willems, Loek; van de Veerdonk, Frank L; Giamarellos-Bourboulis, Evangelos J; Toonen, Erik J M; Joosten, Leo A B; Jaeger, Martin; ...
    Persistent Identifiers

    Abstract Background Excessive activation of immune responses in coronavirus disease 2019 (COVID-19) is considered to be related to disease severity, complications, and mortality rate. The complement system is an important component of innate immunity and can stimulate i...

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Gerco den Hartog; Rutger M. Schepp; Marjan Kuijer; Corine H. GeurtsvanKessel; Josine van Beek; Nynke Y. Rots; Marion Koopmans; Fiona R. M. van der Klis; Robert S. van Binnendijk;

    Detection of SARS-CoV-2–specific antibodies is instrumental to study seroprevalence and immune protection to the virus. We validated a multiplex assay to detect antibodies to SARS-CoV-2 N, S1, and RBD, and provide a framework to perform accurate serosurveys for COVID-19...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Pengfei Li; Jiaye Liu; Zhongren Ma; Wichor M. Bramer; Maikel P. Peppelenbosch; Qiuwei Pan;
    Persistent Identifiers
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  • publication . Article . 2018
    Open Access English
    Authors:
    Patience K. Kiyuka; Charles N. Agoti; Patrick K. Munywoki; Regina Njeru; Anne Bett; James R. Otieno; Grieven P Otieno; Everlyn Kamau; Taane G. Clark; László van den Hoek; ...
    Persistent Identifiers
    Project: UKRI | Geographic genetic profil... (MR/M01360X/1), UKRI | The interactions between ... (MR/K000551/1), UKRI | Zika: Zika virus surveill... (MC_PC_15103), WT | Defining pathways of resp... (102975), UKRI | Understanding the transmi... (MR/N010469/1)

    Infections with human coronavirus NL63 are common and reinfections occur repeatedly throughout life. A subset of repeat infections show enhanced virus replication with no evidence of genotype switching, indicating that initial exposure is insufficient to elicit a protec...

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  • publication . Article . 2017
    Open Access
    Authors:
    Anne W. Rimoin; Kai Lu; Matthew S. Bramble; Imke Steffen; Reena H. Doshi; Nicole A. Hoff; Patrick Mukadi; Bradly P. Nicholson; Vivian H. Alfonso; Gerrard Olinger; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: NIH | University of California ... (5D43TW009343-07), NIH | Serological prevalence of... (5R21AI107420-02)

    Duration of immunity against Ebola virus among survivors remains unclear. We assessed serological immune profiles and retention of Ebola virus neutralizing antibodies in 14 survivors of the 1976 Yambuku outbreak 40 years postinfection, providing the longest documentatio...

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  • publication . Article . 2017
    Open Access
    Authors:
    Reina S. Sikkema; Elmoubasher Farag; Sayed Himatt; Adel K Ibrahim; Hamad Al-Romaihi; Salih A. Al-Marri; Mohamed Al-Thani; Ahmed M. El-Sayed; Mohammed Al-Hajri; Bart L. Haagmans; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: EC | COMPARE (643476), EC | PREPARE (602525)

    Abstract The transmission routes and risk factors for zoonotic Middle East respiratory syndrome coronavirus (MERS-CoV) infections are still unknown. We used the World Health Organization questionnaire for MERS-CoV case-control studies to assess risk factors for human ME...

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7 research outcomes, page 1 of 1