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384 research outcomes, page 1 of 39
  • publication . Article . 2021
    Open Access English
    Authors:
    Pilarowski, Genay; Lebel, Paul; Sunshine, Sara; Liu, Jamin; Crawford, Emily; Marquez, Carina; Rubio, Luis; Chamie, Gabriel; Martinez, Jackie; Peng, James; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    We evaluated the performance of the Abbott BinaxNOW rapid antigen test for coronavirus disease 2019 (Binax-CoV2) to detect virus among persons, regardless of symptoms, at a public plaza site of ongoing community transmission. Titration with cultured severe acute respira...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Avadhanula, Vasanthi; Nicholson, Erin G; Ferlic-Stark, Laura; Piedra, Felipe-Andres; Blunck, Brittani N; Fragoso, Sonia; Bond, Nanette L; Santarcangelo, Patricia L; Ye, Xunyan; McBride, Trevor J; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    Abstract Background During the COVID-19 pandemic, a minority of index cases are associated with a majority of secondary cases suggesting that super-spreaders could drive the pandemic. We identified a phenotype in individuals with extremely high viral load who could act ...

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  • publication . Article . 2021
    Open Access English
    Authors:
    R S, Raman; Barge, Vijaykumar Bhagwan; Darivenula, Anil Kumar; Dandu, Himanshu; Kartha, Rakesh R; Bafna, Varun; Aravinda, Vishaly T; Raghuram, Thummala C;
    Persistent Identifiers
    Publisher: Oxford University Press

    Abstract Background Currently, there is no specific drug for the treatment of COVID-19. Therapeutic benefits of intravenous immunoglobin (IVIG) have been demonstrated in wide range of diseases. The present study is conducted to evaluate the safety and efficacy of IVIG i...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Eelke Brandsma; Han J M P Verhagen; Thijs J.W. van de Laar; Eric C. J. Claas; Marion Cornelissen; Emile van den Akker;
    Persistent Identifiers

    <jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background</jats:title> <jats:p>Recent advances in CRISPR-based diagnostics suggest that DETECTR, a combination of reverse-transcriptase loop-mediated isothermal amplification (RT-LAMP) and subsequent Cas12 bystan...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Kidd, Michael; Richter, Alex; Best, Angus; Cumley, Nicola; Mirza, Jeremy; Percival, Benita; Mayhew, Megan; Megram, Oliver; Ashford, Fiona; White, Thomas; ...
    Persistent Identifiers
    Publisher: Oxford University Press

    Abstract A SARS-CoV-2 variant B1.1.7 containing a mutation Δ69/70 has spread rapidly in the UK and shows an identifiable profile in ThermoFisher TaqPath RTqPCR (S-gene target failure; SGTF). We analysed recent test data for trends and significance. Linked Ct values for ...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Richards, Katherine A; Glover, Maryah; Crawford, Jeremy C; Thomas, Paul; White, Chantelle; Sant, Andrea J;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    Abstract Repeated infections with endemic human coronaviruses are thought to reflect lack of long-lasting protective immunity. Here, we evaluate circulating human CD4 T cells collected prior to 2020 for reactivity towards hCoV spike proteins, probing for the ability to ...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Tarhini, Hassan; Recoing, Amélie; Bridier-Nahmias, Antoine; Rahi, Mayda; Lambert, Céleste; Martres, Pascale; Lucet, Jean-Christophe; Rioux, Christophe; Bouzid, Donia; Lebourgeois, Samuel; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    Abstract Guidelines for stopping COVID-19 patient isolation are mainly symptom-based, with isolation for 10 to 20 days depending on their condition. Here, we describe three deeply immunocompromised patients, each with different clinical evolutions. Asymptomatic carriage...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Dillner, Joakim; Elfström, K Miriam; Blomqvist, Jonas; Engstrand, Lars; Uhlén, Mathias; Eklund, Carina; Boulund, Fredrik; Lagheden, Camilla; Hamsten, Marica; Nordqvist-Kleppe, Sara; ...
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    Publisher: Oxford University Press

    Abstract Background Whether SARS-CoV-2 positivity among symptomatic subjects reflects past or future disease may be difficult to ascertain. Methods We tested a cohort of 9449 employees at work at the Karolinska University Hospital, Stockholm, Sweden for SARS-CoV-2 RNA a...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Lemieux, Jacob E; Li, Jonathan Z;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
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  • publication . Article . 2021
    Open Access English
    Authors:
    Janssen, Nico A F; Grondman, Inge; de Nooijer, Aline H; Boahen, Collins K; Koeken, Valerie A C M; Matzaraki, Vasiliki; Kumar, Vinod; He, Xuehui; Kox, Matthijs; Koenen, Hans J P M; ...
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    Publisher: Oxford University Press (OUP)

    Abstract The clinical spectrum of COVID-19 varies and the differences in host response characterizing this variation have not been fully elucidated. COVID-19 disease severity correlates with an excessive pro-inflammatory immune response and profound lymphopenia. Inflamm...

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384 research outcomes, page 1 of 39