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323 research outcomes, page 1 of 33
  • publication . Article . 2021
    Open Access English
    Authors:
    Li, Jin-Yan; Wang, Qiong; Liao, Ce-Heng; Qiu, Ye; Ge, Xing-Yi;
    Persistent Identifiers
    Publisher: Elsevier B.V.

    Bats carry diverse severe acute respiratory syndrome-related coronaviruses (SARSr-CoVs). The suspected interspecies transmission of SARSr-CoVs from bats to humans has caused two severe CoV pandemics, the SARS pandemic in 2003 and the recent COVID-19 pandemic. The recept...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Scagnolari, Carolina; Pierangeli, Alessandra; Frasca, Federica; Bitossi, Camilla; Viscido, Agnese; Oliveto, Giuseppe; Scordio, Mirko; Mazzuti, Laura; Di Carlo, Daniele; Gentile, Massimo; ...
    Publisher: Elsevier BV

    Highlights • SARS-CoV-2 infected patients have a differential IFN response. • IFN-stimulated genes levels are reduced in critically-ill patients. • SARS-CoV-2 viral load correlated to IFN-stimulated genes levels.

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  • publication . Article . 2021
    Open Access English
    Authors:
    Roy, Sylvie; Ghani, Karim; de Campos-Lima, Pedro O.; Caruso, Manuel;
    Persistent Identifiers
    Publisher: Elsevier B.V.

    In this study, we showed that a codon optimized version of the spike (S) protein of SARS-CoV-2 can migrate to the cell membrane. However, efficient production of Moloney murine leukemia (MLV) infectious viral particles was only achieved with stable expression of a short...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Ke, Wenting; Wu, Xiaoli; Fang, Puxian; Zhou, Yanrong; Fang, Liurong; Xiao, Shaobo;
    Publisher: Elsevier BV

    Highlights • PDCoV infection upregulates CH25H expression in IPI-FX cells. • CH25H inhibits PDCoV infection not absolutely depending on its enzymatic activity. • 25HC inhibits PDCoV replication by inhibiting viral invasion.

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  • publication . Article . 2021
    Open Access English
    Authors:
    Kaur, Taruneet; Kapila, Suman; Kapila, Rajeev; Kumar, Sandeep; Upadhyay, Divya; Kaur, Manjeet; Sharma, Chandresh;
    Publisher: Elsevier BV

    Graphical abstract

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  • publication . Article . 2021
    Open Access English
    Authors:
    Tan, Jiahong; Yuan, Yuan; Xu, Cheng; Song, Chunyan; Liu, Dan; Ma, Ding; Gao, Qinglei;
    Publisher: Elsevier BV

    Coronavirus disease 19 (COVID-19) has posed serious threats to the general population. To relieve the crisis, a comparison of drug effects against COVID-19 is instructive. Between January 27, 2020 and March 21, 2020, a total of 333 patients treated with arbidol, cortico...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Safari, Fatemeh; Afarid, Mohammad; Rastegari, Banafsheh; Borhani-Haghighi, Afshin; Barekati-Mowahed, Mazyar; Behzad-Behbahani, Abbas;
    Publisher: Elsevier BV

    Highlights • SARS-CoV-2 has infected millions people worldwide with numerous deaths since December 2019. • Type V and VI CRISPR enzymes are efficient agents for diagnosis and combating single-stranded RNA viruses such as SARS-CoV-2. • DETECTR and SHERLOCK represent rapi...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Miranda, Renan Lyra; Guterres, Alexandro; de Azeredo Lima, Carlos Henrique; Filho, Paulo Niemeyer; Gadelha, Mônica R.;
    Publisher: Elsevier B.V.

    Knowledge of viral load is essential to formulate strategies for antiviral treatment, vaccination, and epidemiological control of COVID-19. Moreover, identification of patients with high viral loads can also be useful to understand risk factors such as age, comorbiditie...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Akiyama, Yukinori; Sakashita, Kyoya; Arihara, Masayasu; Kimura, Yusuke; Komatsu, Katsuya; Mikami, Takeshi; Mikuni, Nobuhiro;
    Persistent Identifiers
    Publisher: Elsevier BV
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  • publication . Article . 2021
    Open Access
    Authors:
    Malek, Abdul; Hoque, Ashabul;
    Persistent Identifiers
    Publisher: Elsevier BV
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323 research outcomes, page 1 of 33