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description Publicationkeyboard_double_arrow_right Article 2021 Italy, Denmark, Netherlands, Italy, Italy, Sweden, Italy, Sweden, Netherlands, Finland, Italy, Germany, Italy, Netherlands, Netherlands, Italy, SpainPublisher:Springer Science and Business Media LLC Publicly fundedFunded by:EC | SoBigData-PlusPlusEC| SoBigData-PlusPlusMirco Nanni; Gennady Andrienko; Albert-László Barabási; Chiara Boldrini; Francesco Bonchi; Ciro Cattuto; Francesca Chiaromonte; Giovanni Comandé; Marco Conti; Mark Coté; Frank Dignum; Virginia Dignum; Josep Domingo-Ferrer; Paolo Ferragina; Fosca Giannotti; Riccardo Guidotti; Dirk Helbing; Kimmo Kaski; János Kertész; Sune Lehmann; Bruno Lepri; Paul Lukowicz; Stan Matwin; David Megías Jiménez; Anna Monreale; Katharina Morik; Nuria Oliver; Andrea Passarella; Andrea Passerini; Dino Pedreschi; Alex Pentland; Fabio Pianesi; Francesca Pratesi; Salvatore Rinzivillo; Salvatore Ruggieri; Arno Siebes; Vicenç Torra; Roberto Trasarti; Jeroen van den Hoven; Alessandro Vespignani;pmid: 33551673
pmc: PMC7851322
handle: 11568/1115253 , 11382/533311 , 11572/268931 , 11568/1041158 , 11572/330883 , 10609/125306 , 10609/147629 , 1874/410231 , 2318/1764435 , 11384/113354
pmid: 33551673
pmc: PMC7851322
handle: 11568/1115253 , 11382/533311 , 11572/268931 , 11568/1041158 , 11572/330883 , 10609/125306 , 10609/147629 , 1874/410231 , 2318/1764435 , 11384/113354
The rapid dynamics of COVID-19 calls for quick and effective tracking of virus transmission chains and early detection of outbreaks, especially in the “phase 2” of the pandemic, when lockdown and other restriction measures are progressively withdrawn, in order to avoid or minimize contagion resurgence. For this purpose, contact-tracing apps are being proposed for large scale adoption by many countries. A centralized approach, where data sensed by the app are all sent to a nation-wide server, raises concerns about citizens’ privacy and needlessly strong digital surveillance, thus alerting us to the need to minimize personal data collection and avoiding location tracking. We advocate the conceptual advantage of a decentralized approach, where both contact and location data are collected exclusively in individual citizens’ “personal data stores”, to be shared separately and selectively (e.g., with a backend system, but possibly also with other citizens), voluntarily, only when the citizen has tested positive for COVID-19, and with a privacy preserving level of granularity. This approach better protects the personal sphere of citizens and affords multiple benefits: it allows for detailed information gathering for infected people in a privacy-preserving fashion; and, in turn this enables both contact tracing, and, the early detection of outbreak hotspots on more finely-granulated geographic scale. The decentralized approach is also scalable to large populations, in that only the data of positive patients need be handled at a central level. Our recommendation is two-fold. First to extend existing decentralized architectures with a light touch, in order to manage the collection of location data locally on the device, and allow the user to share spatio-temporal aggregates—if and when they want and for specific aims—with health authorities, for instance. Second, we favour a longer-term pursuit of realizing a Personal Data Store vision, giving users the opportunity to contribute to collective good in the measure they want, enhancing self-awareness, and cultivating collective efforts for rebuilding society. Supplement 1
Archivio Istituziona... arrow_drop_down Ethics and Information Technology; Recolector de Ciencia Abierta, RECOLECTA; Archivio della Ricerca - Università di Pisa; Archivio della ricerca della Scuola Superiore Sant'Anna; NARCIS; Archivio istituzionale della Ricerca - Scuola Normale Superiore; IRIS - Institutional Research Information System of the University of TrentoArticle . 2021 . 2020 . 2023 . Peer-reviewedLicense: CC BYData sources: Recolector de Ciencia Abierta, RECOLECTA; Archivio della Ricerca - Università di Pisa; Sygma; Crossref; Archivio della ricerca della Scuola Superiore Sant'Anna; NARCIS; Archivio istituzionale della Ricerca - Scuola Normale Superiore; IRIS - Institutional Research Information System of the University of TrentoNARCIS; TU Delft RepositoryArticle . 2021CORE (RIOXX-UK Aggregator)Article . 2021Full-Text: https://openaccess.city.ac.uk/id/eprint/26562/1/Nanni2021_Article_GiveMoreDataAwarenessAndContro.pdfData sources: CORE (RIOXX-UK Aggregator)Europe PubMed CentralArticle . 2021Full-Text: http://europepmc.org/articles/PMC7851322Data sources: PubMed CentralNARCIS; TU Delft RepositoryArticle . 2020Aaltodoc Publication ArchiveArticle . 2020 . Peer-reviewedData sources: Aaltodoc Publication ArchiveAaltodoc Publication ArchiveArticle . 2021 . Peer-reviewedData sources: Aaltodoc Publication ArchiveRecolector de Ciencia Abierta, RECOLECTAArticle . 2020License: CC BY NC NDData sources: Recolector de Ciencia Abierta, RECOLECTAOnline Research Database In TechnologyArticle . 2021Data sources: Online Research Database In TechnologyNARCIS; Utrecht University RepositoryArticle . 2020Archivio della ricerca della Scuola Superiore Sant'AnnaArticle . 2021Data sources: Archivio della ricerca della Scuola Superiore Sant'AnnaArchivio della Ricerca - Università di PisaArticle . 2020Data sources: Archivio della Ricerca - Università di PisaArchivio della Ricerca - Università di PisaArticle . 2020Data sources: Archivio della Ricerca - Università di PisaArchivio della Ricerca - Università di PisaArticle . 2021Data sources: Archivio della Ricerca - Università di Pisaadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 31 citations 31 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!visibility 65visibility views 65 download downloads 59 Powered bymore_vert Archivio Istituziona... arrow_drop_down Ethics and Information Technology; Recolector de Ciencia Abierta, RECOLECTA; Archivio della Ricerca - Università di Pisa; Archivio della ricerca della Scuola Superiore Sant'Anna; NARCIS; Archivio istituzionale della Ricerca - Scuola Normale Superiore; IRIS - Institutional Research Information System of the University of TrentoArticle . 2021 . 2020 . 2023 . Peer-reviewedLicense: CC BYData sources: Recolector de Ciencia Abierta, RECOLECTA; Archivio della Ricerca - Università di Pisa; Sygma; Crossref; Archivio della ricerca della Scuola Superiore Sant'Anna; NARCIS; Archivio istituzionale della Ricerca - Scuola Normale Superiore; IRIS - Institutional Research Information System of the University of TrentoNARCIS; TU Delft RepositoryArticle . 2021CORE (RIOXX-UK Aggregator)Article . 2021Full-Text: https://openaccess.city.ac.uk/id/eprint/26562/1/Nanni2021_Article_GiveMoreDataAwarenessAndContro.pdfData sources: CORE (RIOXX-UK Aggregator)Europe PubMed CentralArticle . 2021Full-Text: http://europepmc.org/articles/PMC7851322Data sources: PubMed CentralNARCIS; TU Delft RepositoryArticle . 2020Aaltodoc Publication ArchiveArticle . 2020 . Peer-reviewedData sources: Aaltodoc Publication ArchiveAaltodoc Publication ArchiveArticle . 2021 . Peer-reviewedData sources: Aaltodoc Publication ArchiveRecolector de Ciencia Abierta, RECOLECTAArticle . 2020License: CC BY NC NDData sources: Recolector de Ciencia Abierta, RECOLECTAOnline Research Database In TechnologyArticle . 2021Data sources: Online Research Database In TechnologyNARCIS; Utrecht University RepositoryArticle . 2020Archivio della ricerca della Scuola Superiore Sant'AnnaArticle . 2021Data sources: Archivio della ricerca della Scuola Superiore Sant'AnnaArchivio della Ricerca - Università di PisaArticle . 2020Data sources: Archivio della Ricerca - Università di PisaArchivio della Ricerca - Università di PisaArticle . 2020Data sources: Archivio della Ricerca - Università di PisaArchivio della Ricerca - Università di PisaArticle . 2021Data sources: Archivio della Ricerca - Università di Pisaadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2019 Denmark, NetherlandsPublisher:Public Library of Science (PLoS) Funded by:EC | COMPAREEC| COMPARERene S. Hendriksen; Oksana Lukjancenko; Patrick Munk; Mathis Hjort Hjelmsø; Jennifer R. Verani; Eric Ng’eno; Godfrey Bigogo; Samuel Kiplangat; Traoré Oumar; Lasse Bergmark; Timo Röder; John Neatherlin; Onyango Clayton; Tine Hald; Susanne Karlsmose; Sünje Johanna Pamp; Barry S. Fields; Joel M. Montgomery; Frank Møller Aarestrup;BACKGROUND: Worldwide, the number of emerging and re-emerging infectious diseases is increasing, highlighting the importance of global disease pathogen surveillance. Traditional population-based methods may fail to capture important events, particularly in settings with limited access to health care, such as urban informal settlements. In such environments, a mixture of surface water runoff and human feces containing pathogenic microorganisms could be used as a surveillance surrogate.METHOD: We conducted a temporal metagenomic analysis of urban sewage from Kibera, an urban informal settlement in Nairobi, Kenya, to detect and quantify bacterial and associated antimicrobial resistance (AMR) determinants, viral and parasitic pathogens. Data were examined in conjunction with data from ongoing clinical infectious disease surveillance.RESULTS: A large variation of read abundances related to bacteria, viruses, and parasites of medical importance, as well as bacterial associated antimicrobial resistance genes over time were detected. Significant increased abundances were observed for a number of bacterial pathogens coinciding with higher abundances of AMR genes. Vibrio cholerae as well as rotavirus A, among other virus peaked in several weeks during the study period whereas Cryptosporidium spp. and Giardia spp, varied more over time.CONCLUSION: The metagenomic surveillance approach for monitoring circulating pathogens in sewage was able to detect putative pathogen and resistance loads in an urban informal settlement. Thus, valuable if generated in real time to serve as a comprehensive infectious disease agent surveillance system with the potential to guide disease prevention and treatment. The approach may lead to a paradigm shift in conducting real-time global genomics-based surveillance in settings with limited access to health care.
PLoS ONE; NARCIS arrow_drop_down Europe PubMed CentralArticle . 2019Full-Text: http://europepmc.org/articles/PMC6786639Data sources: PubMed CentralOnline Research Database In TechnologyArticle . 2019Data sources: Online Research Database In Technologyadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1371/journal.pone.0222531&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 25 citations 25 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!more_vert PLoS ONE; NARCIS arrow_drop_down Europe PubMed CentralArticle . 2019Full-Text: http://europepmc.org/articles/PMC6786639Data sources: PubMed CentralOnline Research Database In TechnologyArticle . 2019Data sources: Online Research Database In Technologyadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1371/journal.pone.0222531&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2019 NetherlandsPublisher:Springer Science and Business Media LLC Hunsperger, Elizabeth; Juma, Bonventure; Onyango, Clayton; Ochieng, John B.; Omballa, Victor; Fields, Barry S.; Njenga, M. Kariuki; Mwangi, Jane; Bigogo, Godfrey; Omore, Richard; Otieno, Nancy; Chaves, Sandra S.; Munyua, Peninah; Njau, Daniel Macharia; Verani, Jennifer; Lowther, Sara; Breiman, Robert F.; Montgomery, Joel M.; de Cock, Kevin M.; Widdowson, Marc-Alain; Apondi, Evans; Nyaundi, Jeremiah; Mayieka, Lillian; Mwasi, Lydia; Wamola, Newton; Gikunju, Stella; Kikwai, Gilbert; Ochieng, Caroline; Mujete, Timothy; Odhiambo, Dennis; Ogolla, Melvin Ochieng; Abisinwa, Everlyne; Mugoh, Robert; Odiembo, Herrine; Ade, Frederick; Onyiengo, Jane Juma; Katieno, Jim; Emojong, Patrick; Lidechi, Shirley; Achieng, Baryl; Okloyo, Arthur; Odindo, Dorothy; Agai, Wilfrida; Oumo, Carol; Arita, Lillian; Abuom, Jairus; Amon, Derrick; Achieng, Loicer; Osita, Mike; Alando, Mose; Mott, Josh; Njenga, Henry; Ndegwa, Linus; Joseph, Rachael; Ope, Maurice; Okello, Charles; Wachira, Cyrus; Wamburu, Kabura; Wakhule, Lilian; Jeruto, Carolyne; Gikundi, Solomon; Nderitu, Leonard; Omulo, Sylvia; Wanjala, Rose; Obiya, Joshua; Ngotho, Patricia; Ngore, Regina; Awiti, George; Gumbi, Wilson; Korir, Kipyegon; Oungo, Collins;Abstract Since 1979, multiple CDC Kenya programs have supported the development of diagnostic expertise and laboratory capacity in Kenya. In 2004, CDC’s Global Disease Detection (GDD) program within the Division of Global Health Protection in Kenya (DGHP-Kenya) initiated close collaboration with Kenya Medical Research Institute (KEMRI) and developed a laboratory partnership called the Diagnostic and Laboratory Systems Program (DLSP). DLSP built onto previous efforts by malaria, human immunodeficiency virus (HIV) and tuberculosis (TB) programs and supported the expansion of the diagnostic expertise and capacity in KEMRI and the Ministry of Health. First, DLSP developed laboratory capacity for surveillance of diarrheal, respiratory, zoonotic and febrile illnesses to understand the etiology burden of these common illnesses and support evidenced-based decisions on vaccine introductions and recommendations in Kenya. Second, we have evaluated and implemented new diagnostic technologies such as TaqMan Array Cards (TAC) to detect emerging or reemerging pathogens and have recently added a next generation sequencer (NGS). Third, DLSP provided rapid laboratory diagnostic support for outbreak investigation to Kenya and regional countries. Fourth, DLSP has been assisting the Kenya National Public Health laboratory-National Influenza Center and microbiology reference laboratory to obtain World Health Organization (WHO) certification and ISO15189 accreditation respectively. Fifth, we have supported biosafety and biosecurity curriculum development to help Kenyan laboratories safely and appropriately manage infectious pathogens. These achievements, highlight how in collaboration with existing CDC programs working on HIV, tuberculosis and malaria, the Global Health Security Agenda can have significantly improve public health in Kenya and the region. Moreover, Kenya provides an example as to how laboratory science can help countries detect and control of infectious disease outbreaks and other public health threats more rapidly, thus enhancing global health security.
BMC Public Health arrow_drop_down BMC Public HealthArticle . 2019Full-Text: http://europepmc.org/articles/PMC6696698Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1186/s12889-019-6770-9&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesgold 15 citations 15 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert BMC Public Health arrow_drop_down BMC Public HealthArticle . 2019Full-Text: http://europepmc.org/articles/PMC6696698Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1186/s12889-019-6770-9&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2019 NetherlandsPublisher:Springer Science and Business Media LLC Funded by:WTWTPeninah M. Munyua; M. Kariuki Njenga; Eric M. Osoro; Clayton O. Onyango; Austine O. Bitek; Athman Mwatondo; Mathew K. Muturi; Norah Musee; Godfrey Bigogo; Elkanah Otiang; Fredrick Ade; Sara A. Lowther; Robert F. Breiman; John Neatherlin; Joel Montgomery; Marc-Alain Widdowson;Abstract More than 75% of emerging infectious diseases are zoonotic in origin and a transdisciplinary, multi-sectoral One Health approach is a key strategy for their effective prevention and control. In 2004, US Centers for Disease Control and Prevention office in Kenya (CDC Kenya) established the Global Disease Detection Division of which one core component was to support, with other partners, the One Health approach to public health science. After catalytic events such as the global expansion of highly pathogenic H5N1 and the 2006 East African multi-country outbreaks of Rift Valley Fever, CDC Kenya supported key Kenya government institutions including the Ministry of Health and the Ministry of Agriculture, Livestock, and Fisheries to establish a framework for multi-sectoral collaboration at national and county level and a coordination office referred to as the Zoonotic Disease Unit (ZDU). The ZDU has provided Kenya with an institutional framework to highlight the public health importance of endemic and epidemic zoonoses including RVF, rabies, brucellosis, Middle East Respiratory Syndrome Coronavirus, anthrax and other emerging issues such as anti-microbial resistance through capacity building programs, surveillance, workforce development, research, coordinated investigation and outbreak response. This has led to improved outbreak response, and generated data (including discovery of new pathogens) that has informed disease control programs to reduce burden of and enhance preparedness for endemic and epidemic zoonotic diseases, thereby enhancing global health security. Since 2014, the Global Health Security Agenda implemented through CDC Kenya and other partners in the country has provided additional impetus to maintain this effort and Kenya’s achievement now serves as a model for other countries in the region. Significant gaps remain in implementation of the One Health approach at subnational administrative levels; there are sustainability concerns, competing priorities and funding deficiencies.
BMC Public Health arrow_drop_down BMC Public HealthArticle . 2019Full-Text: http://europepmc.org/articles/PMC6696663Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1186/s12889-019-6772-7&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesgold 62 citations 62 popularity Top 1% influence Top 10% impulse Top 1% Powered by BIP!more_vert BMC Public Health arrow_drop_down BMC Public HealthArticle . 2019Full-Text: http://europepmc.org/articles/PMC6696663Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1186/s12889-019-6772-7&type=result"></script>'); --> </script>
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description Publicationkeyboard_double_arrow_right Article 2021 Italy, Denmark, Netherlands, Italy, Italy, Sweden, Italy, Sweden, Netherlands, Finland, Italy, Germany, Italy, Netherlands, Netherlands, Italy, SpainPublisher:Springer Science and Business Media LLC Publicly fundedFunded by:EC | SoBigData-PlusPlusEC| SoBigData-PlusPlusMirco Nanni; Gennady Andrienko; Albert-László Barabási; Chiara Boldrini; Francesco Bonchi; Ciro Cattuto; Francesca Chiaromonte; Giovanni Comandé; Marco Conti; Mark Coté; Frank Dignum; Virginia Dignum; Josep Domingo-Ferrer; Paolo Ferragina; Fosca Giannotti; Riccardo Guidotti; Dirk Helbing; Kimmo Kaski; János Kertész; Sune Lehmann; Bruno Lepri; Paul Lukowicz; Stan Matwin; David Megías Jiménez; Anna Monreale; Katharina Morik; Nuria Oliver; Andrea Passarella; Andrea Passerini; Dino Pedreschi; Alex Pentland; Fabio Pianesi; Francesca Pratesi; Salvatore Rinzivillo; Salvatore Ruggieri; Arno Siebes; Vicenç Torra; Roberto Trasarti; Jeroen van den Hoven; Alessandro Vespignani;pmid: 33551673
pmc: PMC7851322
handle: 11568/1115253 , 11382/533311 , 11572/268931 , 11568/1041158 , 11572/330883 , 10609/125306 , 10609/147629 , 1874/410231 , 2318/1764435 , 11384/113354
pmid: 33551673
pmc: PMC7851322
handle: 11568/1115253 , 11382/533311 , 11572/268931 , 11568/1041158 , 11572/330883 , 10609/125306 , 10609/147629 , 1874/410231 , 2318/1764435 , 11384/113354
The rapid dynamics of COVID-19 calls for quick and effective tracking of virus transmission chains and early detection of outbreaks, especially in the “phase 2” of the pandemic, when lockdown and other restriction measures are progressively withdrawn, in order to avoid or minimize contagion resurgence. For this purpose, contact-tracing apps are being proposed for large scale adoption by many countries. A centralized approach, where data sensed by the app are all sent to a nation-wide server, raises concerns about citizens’ privacy and needlessly strong digital surveillance, thus alerting us to the need to minimize personal data collection and avoiding location tracking. We advocate the conceptual advantage of a decentralized approach, where both contact and location data are collected exclusively in individual citizens’ “personal data stores”, to be shared separately and selectively (e.g., with a backend system, but possibly also with other citizens), voluntarily, only when the citizen has tested positive for COVID-19, and with a privacy preserving level of granularity. This approach better protects the personal sphere of citizens and affords multiple benefits: it allows for detailed information gathering for infected people in a privacy-preserving fashion; and, in turn this enables both contact tracing, and, the early detection of outbreak hotspots on more finely-granulated geographic scale. The decentralized approach is also scalable to large populations, in that only the data of positive patients need be handled at a central level. Our recommendation is two-fold. First to extend existing decentralized architectures with a light touch, in order to manage the collection of location data locally on the device, and allow the user to share spatio-temporal aggregates—if and when they want and for specific aims—with health authorities, for instance. Second, we favour a longer-term pursuit of realizing a Personal Data Store vision, giving users the opportunity to contribute to collective good in the measure they want, enhancing self-awareness, and cultivating collective efforts for rebuilding society. Supplement 1
Archivio Istituziona... arrow_drop_down Ethics and Information Technology; Recolector de Ciencia Abierta, RECOLECTA; Archivio della Ricerca - Università di Pisa; Archivio della ricerca della Scuola Superiore Sant'Anna; NARCIS; Archivio istituzionale della Ricerca - Scuola Normale Superiore; IRIS - Institutional Research Information System of the University of TrentoArticle . 2021 . 2020 . 2023 . Peer-reviewedLicense: CC BYData sources: Recolector de Ciencia Abierta, RECOLECTA; Archivio della Ricerca - Università di Pisa; Sygma; Crossref; Archivio della ricerca della Scuola Superiore Sant'Anna; NARCIS; Archivio istituzionale della Ricerca - Scuola Normale Superiore; IRIS - Institutional Research Information System of the University of TrentoNARCIS; TU Delft RepositoryArticle . 2021CORE (RIOXX-UK Aggregator)Article . 2021Full-Text: https://openaccess.city.ac.uk/id/eprint/26562/1/Nanni2021_Article_GiveMoreDataAwarenessAndContro.pdfData sources: CORE (RIOXX-UK Aggregator)Europe PubMed CentralArticle . 2021Full-Text: http://europepmc.org/articles/PMC7851322Data sources: PubMed CentralNARCIS; TU Delft RepositoryArticle . 2020Aaltodoc Publication ArchiveArticle . 2020 . Peer-reviewedData sources: Aaltodoc Publication ArchiveAaltodoc Publication ArchiveArticle . 2021 . Peer-reviewedData sources: Aaltodoc Publication ArchiveRecolector de Ciencia Abierta, RECOLECTAArticle . 2020License: CC BY NC NDData sources: Recolector de Ciencia Abierta, RECOLECTAOnline Research Database In TechnologyArticle . 2021Data sources: Online Research Database In TechnologyNARCIS; Utrecht University RepositoryArticle . 2020Archivio della ricerca della Scuola Superiore Sant'AnnaArticle . 2021Data sources: Archivio della ricerca della Scuola Superiore Sant'AnnaArchivio della Ricerca - Università di PisaArticle . 2020Data sources: Archivio della Ricerca - Università di PisaArchivio della Ricerca - Università di PisaArticle . 2020Data sources: Archivio della Ricerca - Università di PisaArchivio della Ricerca - Università di PisaArticle . 2021Data sources: Archivio della Ricerca - Università di Pisaadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 31 citations 31 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!visibility 65visibility views 65 download downloads 59 Powered bymore_vert Archivio Istituziona... arrow_drop_down Ethics and Information Technology; Recolector de Ciencia Abierta, RECOLECTA; Archivio della Ricerca - Università di Pisa; Archivio della ricerca della Scuola Superiore Sant'Anna; NARCIS; Archivio istituzionale della Ricerca - Scuola Normale Superiore; IRIS - Institutional Research Information System of the University of TrentoArticle . 2021 . 2020 . 2023 . Peer-reviewedLicense: CC BYData sources: Recolector de Ciencia Abierta, RECOLECTA; Archivio della Ricerca - Università di Pisa; Sygma; Crossref; Archivio della ricerca della Scuola Superiore Sant'Anna; NARCIS; Archivio istituzionale della Ricerca - Scuola Normale Superiore; IRIS - Institutional Research Information System of the University of TrentoNARCIS; TU Delft RepositoryArticle . 2021CORE (RIOXX-UK Aggregator)Article . 2021Full-Text: https://openaccess.city.ac.uk/id/eprint/26562/1/Nanni2021_Article_GiveMoreDataAwarenessAndContro.pdfData sources: CORE (RIOXX-UK Aggregator)Europe PubMed CentralArticle . 2021Full-Text: http://europepmc.org/articles/PMC7851322Data sources: PubMed CentralNARCIS; TU Delft RepositoryArticle . 2020Aaltodoc Publication ArchiveArticle . 2020 . Peer-reviewedData sources: Aaltodoc Publication ArchiveAaltodoc Publication ArchiveArticle . 2021 . Peer-reviewedData sources: Aaltodoc Publication ArchiveRecolector de Ciencia Abierta, RECOLECTAArticle . 2020License: CC BY NC NDData sources: Recolector de Ciencia Abierta, RECOLECTAOnline Research Database In TechnologyArticle . 2021Data sources: Online Research Database In TechnologyNARCIS; Utrecht University RepositoryArticle . 2020Archivio della ricerca della Scuola Superiore Sant'AnnaArticle . 2021Data sources: Archivio della ricerca della Scuola Superiore Sant'AnnaArchivio della Ricerca - Università di PisaArticle . 2020Data sources: Archivio della Ricerca - Università di PisaArchivio della Ricerca - Università di PisaArticle . 2020Data sources: Archivio della Ricerca - Università di PisaArchivio della Ricerca - Università di PisaArticle . 2021Data sources: Archivio della Ricerca - Università di Pisaadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s10676-020-09572-w&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2019 Denmark, NetherlandsPublisher:Public Library of Science (PLoS) Funded by:EC | COMPAREEC| COMPARERene S. Hendriksen; Oksana Lukjancenko; Patrick Munk; Mathis Hjort Hjelmsø; Jennifer R. Verani; Eric Ng’eno; Godfrey Bigogo; Samuel Kiplangat; Traoré Oumar; Lasse Bergmark; Timo Röder; John Neatherlin; Onyango Clayton; Tine Hald; Susanne Karlsmose; Sünje Johanna Pamp; Barry S. Fields; Joel M. Montgomery; Frank Møller Aarestrup;BACKGROUND: Worldwide, the number of emerging and re-emerging infectious diseases is increasing, highlighting the importance of global disease pathogen surveillance. Traditional population-based methods may fail to capture important events, particularly in settings with limited access to health care, such as urban informal settlements. In such environments, a mixture of surface water runoff and human feces containing pathogenic microorganisms could be used as a surveillance surrogate.METHOD: We conducted a temporal metagenomic analysis of urban sewage from Kibera, an urban informal settlement in Nairobi, Kenya, to detect and quantify bacterial and associated antimicrobial resistance (AMR) determinants, viral and parasitic pathogens. Data were examined in conjunction with data from ongoing clinical infectious disease surveillance.RESULTS: A large variation of read abundances related to bacteria, viruses, and parasites of medical importance, as well as bacterial associated antimicrobial resistance genes over time were detected. Significant increased abundances were observed for a number of bacterial pathogens coinciding with higher abundances of AMR genes. Vibrio cholerae as well as rotavirus A, among other virus peaked in several weeks during the study period whereas Cryptosporidium spp. and Giardia spp, varied more over time.CONCLUSION: The metagenomic surveillance approach for monitoring circulating pathogens in sewage was able to detect putative pathogen and resistance loads in an urban informal settlement. Thus, valuable if generated in real time to serve as a comprehensive infectious disease agent surveillance system with the potential to guide disease prevention and treatment. The approach may lead to a paradigm shift in conducting real-time global genomics-based surveillance in settings with limited access to health care.
PLoS ONE; NARCIS arrow_drop_down Europe PubMed CentralArticle . 2019Full-Text: http://europepmc.org/articles/PMC6786639Data sources: PubMed CentralOnline Research Database In TechnologyArticle . 2019Data sources: Online Research Database In Technologyadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1371/journal.pone.0222531&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 25 citations 25 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!more_vert PLoS ONE; NARCIS arrow_drop_down Europe PubMed CentralArticle . 2019Full-Text: http://europepmc.org/articles/PMC6786639Data sources: PubMed CentralOnline Research Database In TechnologyArticle . 2019Data sources: Online Research Database In Technologyadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1371/journal.pone.0222531&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2019 NetherlandsPublisher:Springer Science and Business Media LLC Hunsperger, Elizabeth; Juma, Bonventure; Onyango, Clayton; Ochieng, John B.; Omballa, Victor; Fields, Barry S.; Njenga, M. Kariuki; Mwangi, Jane; Bigogo, Godfrey; Omore, Richard; Otieno, Nancy; Chaves, Sandra S.; Munyua, Peninah; Njau, Daniel Macharia; Verani, Jennifer; Lowther, Sara; Breiman, Robert F.; Montgomery, Joel M.; de Cock, Kevin M.; Widdowson, Marc-Alain; Apondi, Evans; Nyaundi, Jeremiah; Mayieka, Lillian; Mwasi, Lydia; Wamola, Newton; Gikunju, Stella; Kikwai, Gilbert; Ochieng, Caroline; Mujete, Timothy; Odhiambo, Dennis; Ogolla, Melvin Ochieng; Abisinwa, Everlyne; Mugoh, Robert; Odiembo, Herrine; Ade, Frederick; Onyiengo, Jane Juma; Katieno, Jim; Emojong, Patrick; Lidechi, Shirley; Achieng, Baryl; Okloyo, Arthur; Odindo, Dorothy; Agai, Wilfrida; Oumo, Carol; Arita, Lillian; Abuom, Jairus; Amon, Derrick; Achieng, Loicer; Osita, Mike; Alando, Mose; Mott, Josh; Njenga, Henry; Ndegwa, Linus; Joseph, Rachael; Ope, Maurice; Okello, Charles; Wachira, Cyrus; Wamburu, Kabura; Wakhule, Lilian; Jeruto, Carolyne; Gikundi, Solomon; Nderitu, Leonard; Omulo, Sylvia; Wanjala, Rose; Obiya, Joshua; Ngotho, Patricia; Ngore, Regina; Awiti, George; Gumbi, Wilson; Korir, Kipyegon; Oungo, Collins;Abstract Since 1979, multiple CDC Kenya programs have supported the development of diagnostic expertise and laboratory capacity in Kenya. In 2004, CDC’s Global Disease Detection (GDD) program within the Division of Global Health Protection in Kenya (DGHP-Kenya) initiated close collaboration with Kenya Medical Research Institute (KEMRI) and developed a laboratory partnership called the Diagnostic and Laboratory Systems Program (DLSP). DLSP built onto previous efforts by malaria, human immunodeficiency virus (HIV) and tuberculosis (TB) programs and supported the expansion of the diagnostic expertise and capacity in KEMRI and the Ministry of Health. First, DLSP developed laboratory capacity for surveillance of diarrheal, respiratory, zoonotic and febrile illnesses to understand the etiology burden of these common illnesses and support evidenced-based decisions on vaccine introductions and recommendations in Kenya. Second, we have evaluated and implemented new diagnostic technologies such as TaqMan Array Cards (TAC) to detect emerging or reemerging pathogens and have recently added a next generation sequencer (NGS). Third, DLSP provided rapid laboratory diagnostic support for outbreak investigation to Kenya and regional countries. Fourth, DLSP has been assisting the Kenya National Public Health laboratory-National Influenza Center and microbiology reference laboratory to obtain World Health Organization (WHO) certification and ISO15189 accreditation respectively. Fifth, we have supported biosafety and biosecurity curriculum development to help Kenyan laboratories safely and appropriately manage infectious pathogens. These achievements, highlight how in collaboration with existing CDC programs working on HIV, tuberculosis and malaria, the Global Health Security Agenda can have significantly improve public health in Kenya and the region. Moreover, Kenya provides an example as to how laboratory science can help countries detect and control of infectious disease outbreaks and other public health threats more rapidly, thus enhancing global health security.
BMC Public Health arrow_drop_down BMC Public HealthArticle . 2019Full-Text: http://europepmc.org/articles/PMC6696698Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1186/s12889-019-6770-9&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesgold 15 citations 15 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert BMC Public Health arrow_drop_down BMC Public HealthArticle . 2019Full-Text: http://europepmc.org/articles/PMC6696698Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1186/s12889-019-6770-9&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2019 NetherlandsPublisher:Springer Science and Business Media LLC Funded by:WTWTPeninah M. Munyua; M. Kariuki Njenga; Eric M. Osoro; Clayton O. Onyango; Austine O. Bitek; Athman Mwatondo; Mathew K. Muturi; Norah Musee; Godfrey Bigogo; Elkanah Otiang; Fredrick Ade; Sara A. Lowther; Robert F. Breiman; John Neatherlin; Joel Montgomery; Marc-Alain Widdowson;Abstract More than 75% of emerging infectious diseases are zoonotic in origin and a transdisciplinary, multi-sectoral One Health approach is a key strategy for their effective prevention and control. In 2004, US Centers for Disease Control and Prevention office in Kenya (CDC Kenya) established the Global Disease Detection Division of which one core component was to support, with other partners, the One Health approach to public health science. After catalytic events such as the global expansion of highly pathogenic H5N1 and the 2006 East African multi-country outbreaks of Rift Valley Fever, CDC Kenya supported key Kenya government institutions including the Ministry of Health and the Ministry of Agriculture, Livestock, and Fisheries to establish a framework for multi-sectoral collaboration at national and county level and a coordination office referred to as the Zoonotic Disease Unit (ZDU). The ZDU has provided Kenya with an institutional framework to highlight the public health importance of endemic and epidemic zoonoses including RVF, rabies, brucellosis, Middle East Respiratory Syndrome Coronavirus, anthrax and other emerging issues such as anti-microbial resistance through capacity building programs, surveillance, workforce development, research, coordinated investigation and outbreak response. This has led to improved outbreak response, and generated data (including discovery of new pathogens) that has informed disease control programs to reduce burden of and enhance preparedness for endemic and epidemic zoonotic diseases, thereby enhancing global health security. Since 2014, the Global Health Security Agenda implemented through CDC Kenya and other partners in the country has provided additional impetus to maintain this effort and Kenya’s achievement now serves as a model for other countries in the region. Significant gaps remain in implementation of the One Health approach at subnational administrative levels; there are sustainability concerns, competing priorities and funding deficiencies.
BMC Public Health arrow_drop_down BMC Public HealthArticle . 2019Full-Text: http://europepmc.org/articles/PMC6696663Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1186/s12889-019-6772-7&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesgold 62 citations 62 popularity Top 1% influence Top 10% impulse Top 1% Powered by BIP!more_vert BMC Public Health arrow_drop_down BMC Public HealthArticle . 2019Full-Text: http://europepmc.org/articles/PMC6696663Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1186/s12889-019-6772-7&type=result"></script>'); --> </script>
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