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12 research outcomes, page 1 of 2
  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Al Maani A; Paul H; Azza Al-Rashdi; Wahaibi Aa; Amina Al-Jardani; Al Abri Ama; AlBalushi Mah; Seif Al-Abri; Al Reesi M; Al Maqbali A; ...

    Candida auris has emerged in the past decade as a multi-drug resistant public health threat causing health care outbreaks. Here we report epidemiological, clinical, and microbiological investigations of a C. auris outbreak in a regional Omani hospital between April 2018...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Berto, A.; Pham, H. A.; Thao, T. T. N.; Vy, N. H. T.; Caddy, S. L.; Hiraide, R.; Tue, N. T.; Goodfellow, I.; Carrique-Mas, J. J.; Thwaites, G. E.; ...
    Persistent Identifiers
    Publisher: Wiley
    Project: WT | The epidemiology, genomic... (100087), WT | Unravelling the networks ... (097997), WT | Epidemiology of Human Inf... (098511)

    Summary Viral pathogens account for a significant proportion of the burden of emerging infectious diseases in humans. The Wellcome Trust-Vietnamese Initiative on Zoonotic Infections (WT-VIZIONS) is aiming to understand the circulation of viral zoonotic pathogens in anim...

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  • publication . Article . 2016
    Open Access English
    Authors:
    Do, Lien Anh Ha; Bryant, Juliet E.; Tran, Anh Tuan; Nguyen, Bach Hue; Tran, Thi Thu Loan; Tran, Quynh Huong; Vo, Quoc Bao; Tran Dac, Nguyen Anh; Trinh, Hong Nhien; Nguyen, Thi Thanh Hai; ...
    Persistent Identifiers
    Project: WT | Wellcome Trust Major Over... (077078)

    Background Despite a high burden of respiratory syncytial virus (RSV) infections among children, data on demographic and clinical characteristics of RSV are scarce in low and middle income countries. This study aims to describe the viral etiologies, the demographic, epi...

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  • publication . Article . 2015
    Open Access English
    Authors:
    Yaseen M. Arabi; Hanan H. Balkhy; Ali H. Hajeer; Abderrezak Bouchama; Frederick G. Hayden; Awad Al-Omari; Fahad Al-Hameed; Yusri Taha; Nahoko Shindo; John Whitehead; ...
    Persistent Identifiers
    Publisher: Springer Nature

    As of September 30, 2015, a total of 1589 laboratory-confirmed cases of infection with the Middle East respiratory syndrome coronavirus (MERS-CoV) have been reported to the World Health Organization (WHO). At present there is no effective specific therapy against MERS-C...

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  • publication . Article . Other literature type . 2015
    Open Access
    Authors:
    Maia A. Rabaa; Ngo Tri Tue; Tran My Phuc; Juan Carrique-Mas; Karen Saylors; Matthew Cotten; Juliet E. Bryant; Ho Dang Trung Nghia; Nguyen Van Cuong; Hong Anh Pham; ...
    Project: WT | The epidemiology, genomic... (100087), WT | Epidemiology of Human Inf... (098511)

    <jats:title>Abstract</jats:title> <jats:p>The effect of newly emerging or re-emerging infectious diseases of zoonotic origin in human populations can be potentially catastrophic, and large-scale investigations of such diseases are highly challenging. The monitoring of e...

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  • publication . Article . 2014
    Open Access
    Authors:
    Hoang, Long Truong; Tolfvenstam, Thomas; Ooi, Eng Eong; Khor, Chiea Chuen; Naim, Ahmand Nazri Mohamed; Ho, Eliza Xin Pei; Ong, Swee Hoe; Wertheim, Heiman F; Fox, Annette; Van Vinh Nguyen, Chau; ...
    Persistent Identifiers
    Publisher: Public Library of Science (PLoS)
    Project: WT | Wellcome Trust Major Over... (077078)

    BACKGROUND: The influenza A virus is an RNA virus that is responsible for seasonal epidemics worldwide with up to five million cases of severe illness and 500,000 deaths annually according to the World Health Organization estimates. The factors associated with severe di...

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  • publication . Article . 2014
    Open Access English
    Authors:
    Memish, Ziad A.; Cotten, Matthew; Meyer, Benjamin; Watson, Simon J.; Alsahafi, Abdullah J.; Al Rabeeah, Abdullah A.; Corman, Victor Max; Sieberg, Andrea; Makhdoom, Hatem Q.; Assiri, Abdullah; ...
    Persistent Identifiers
    Project: EC | EMPERIE (223498), WT , EC | ANTIGONE (278976)

    We investigated a case of human infection with Middle East respiratory syndrome coronavirus (MERS-CoV) after exposure to infected camels. Analysis of the whole human-derived virus and 15% of the camel-derived virus sequence yielded nucleotide polymorphism signatures sug...

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  • publication . Article . 2013
    Open Access English
    Authors:
    Lauber, C.; Goeman, J.J.; Parquet, M.D.; Nga, P.T.; Snijder, E.J.; Morita, K.; Gorbalenya, A.E.;
    Publisher: PUBLIC LIBRARY SCIENCE
    Project: EC | SILVER (260644)

    Author Summary RNA viruses include many major pathogens. The adaptation of viruses to their hosts is facilitated by fast mutation and constrained by small genome sizes, which are both due to the extremely high error rate of viral polymerases. Using an innovative computa...

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  • publication . Article . 2012
    Open Access English
    Authors:
    Chris Lauber; John Ziebuhr; Sandra Junglen; Christian Drosten; Florian Zirkel; Phan Thi Nga; Kouichi Morita; Eric J. Snijder; Alexander E. Gorbalenya;
    Project: EC | SILVER (260644), EC | EMPERIE (223498), EC | EVA (228292)

    Recently, two independent surveillance studies in Côte d'Ivoire and Vietnam, respectively, led to the discovery of two mosquito-borne viruses, Cavally virus and Nam Dinh virus, with genome and proteome properties typical for viruses of the order Nidovirales. Using a sta...

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  • publication . Article . 2012
    Open Access English
    Authors:
    Lien Anh Ha, Do; H Rogier, van Doorn; Juliet E, Bryant; My Ngoc, Nghiem; Vinh Chau, Nguyen Van; Cong Khanh, Vo; Minh Dung, Nguyen; Tinh Hien, Tran; Jeremy, Farrar; Menno D, de Jong;
    Project: WT

    Highlights ► A novel real-time RT-PCR using specific locked nucleic acid probes is described. ► The assay is quantitative and distinguishes RSV subgroup A & B. ► Compared with a commercial multiplex PCR using 264 respiratory samplesin Vietnam. ► Sensitivity was signific...

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12 research outcomes, page 1 of 2