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9 research outcomes, page 1 of 1
  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Al Maani A; Paul H; Azza Al-Rashdi; Wahaibi Aa; Amina Al-Jardani; Al Abri Ama; AlBalushi Mah; Seif Al-Abri; Al Reesi M; Al Maqbali A; ...

    Candida auris has emerged in the past decade as a multi-drug resistant public health threat causing health care outbreaks. Here we report epidemiological, clinical, and microbiological investigations of a C. auris outbreak in a regional Omani hospital between April 2018...

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  • publication . Article . Other literature type . 2016
    Open Access English
    Authors:
    Lipsitch, Marc; Barclay, Wendy; Raman, Rahul; Russell, Charles J; Belser, Jessica A; Cobey, Sarah; Kasson, Peter M; Lloyd-Smith, James O; Maurer-Stroh, Sebastian; Riley, Steven; ...
    Persistent Identifiers
    Publisher: eLife Sciences Publications, Ltd
    Project: NIH | Understanding fusion pept... (5R01GM098304-02), NIH | Models for synthesising m... (1U01GM110721-01), NIH | MIDAS Center for Communic... (1U54GM088558-01), WT | Merging theory and field ... (093488), UKRI | Understanding herd immuni... (MR/J008761/1), WT | The life course of human ... (200861), WT | The evolution of influenz... (200187), UKRI | MRC-University of Glasgow... (G0801822), NIH | The biophysical basis of ... (5R01GM088344-03)

    The threat of an influenza A virus pandemic stems from continual virus spillovers from reservoir species, a tiny fraction of which spark sustained transmission in humans. To date, no pandemic emergence of a new influenza strain has been preceded by detection of a closel...

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  • publication . Article . 2015
    Open Access English
    Authors:
    Ermira Tartari; Benedetta Allegranzi; Brenda Ang; Neville Calleja; Peter Collignon; Joost Hopman; Lily Lang; Lai Chee Lee; Moi Lin Ling; Shaheen Mehtar; ...
    Persistent Identifiers
    Publisher: BioMed Central Ltd.

    Findings: Data from 192 medical professionals (one third from Africa) representing 125 hospitals in 45 countries around the globe were obtained through a specifically developed electronic survey. The survey contained 76 specific questions in 7 major sections: Administra...

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  • publication . Article . 2014
    Open Access
    Authors:
    Hoang, Long Truong; Tolfvenstam, Thomas; Ooi, Eng Eong; Khor, Chiea Chuen; Naim, Ahmand Nazri Mohamed; Ho, Eliza Xin Pei; Ong, Swee Hoe; Wertheim, Heiman F; Fox, Annette; Van Vinh Nguyen, Chau; ...
    Persistent Identifiers
    Publisher: Public Library of Science (PLoS)
    Project: WT | Wellcome Trust Major Over... (077078)

    BACKGROUND: The influenza A virus is an RNA virus that is responsible for seasonal epidemics worldwide with up to five million cases of severe illness and 500,000 deaths annually according to the World Health Organization estimates. The factors associated with severe di...

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  • publication . Article . 2014
    Open Access English
    Authors:
    Memish, Ziad A.; Cotten, Matthew; Meyer, Benjamin; Watson, Simon J.; Alsahafi, Abdullah J.; Al Rabeeah, Abdullah A.; Corman, Victor Max; Sieberg, Andrea; Makhdoom, Hatem Q.; Assiri, Abdullah; ...
    Persistent Identifiers
    Project: EC | EMPERIE (223498), WT , EC | ANTIGONE (278976)

    We investigated a case of human infection with Middle East respiratory syndrome coronavirus (MERS-CoV) after exposure to infected camels. Analysis of the whole human-derived virus and 15% of the camel-derived virus sequence yielded nucleotide polymorphism signatures sug...

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  • publication . Other literature type . Article . 2011
    Open Access English
    Authors:
    Teluguakula Narasaraju; Edwin Yang; Ramar Perumal Samy; Huey Hian Ng; Wee Peng Poh; Audrey-Ann Liew; Meng Chee Phoon; Nico van Rooijen; Vincent T. K. Chow;
    Publisher: American Society for Investigative Pathology

    Complications of acute respiratory distress syndrome (ARDS) are common among critically ill patients infected with highly pathogenic influenza viruses. Macrophages and neutrophils constitute the majority of cells recruited into infected lungs, and are associated with im...

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  • publication . Article . 2009
    Open Access
    Authors:
    Zwart, Onno; Veldhuijzen, Irene; Elam, Gillian; Aro, Arja; Abraham, Thomas; Bishop, George; Voeten, Hélène; Richardus, Jan Hendrik; Brug, Hans;

    Springer Open Choice, 21 Feb 2012

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  • publication . Article . 2006
    Open Access
    Authors:
    Jan ter Meulen; Edward Norbert van den Brink; Leo L.M. Poon; Wilfred E. Marissen; Cynthia S. W. Leung; Freek Cox; Chung Y. Cheung; Arjen Q. Bakker; Johannes A. Bogaards; Els van Deventer; ...
    Persistent Identifiers
    Publisher: Public Library of Science (PLoS)

    Two human monoclonal antibodies that bind to different parts of the viral glycoprotein spike show synergistic effects in virus neutralization and suppress the emergence of resistant virus in vitro.

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  • publication . Article . 2006
    Open Access
    Authors:
    Choong-Tat Keng; Yook-Wah Choi; Matthijs R.A. Welkers; Daphne Z. L. Chan; Shuo Shen; Seng Gee Lim; Wanjin Hong; Yee-Joo Tan;
    Persistent Identifiers
    Publisher: Elsevier BV

    AbstractThe severe acute respiratory syndrome coronavirus (SARS-CoV), isolated from humans infected during the peak of epidemic, encodes two accessory proteins termed as 8a and 8b. Interestingly, the SARS-CoV isolated from animals contains an extra 29-nucleotide in this...

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9 research outcomes, page 1 of 1