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The following results are related to COVID-19. Are you interested to view more results? Visit OpenAIRE - Explore.
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1,634 research outcomes, page 1 of 164
  • publication . Other literature type . 2022
    Open Access English
    Authors:
    Ranganathan, E. Sila Ozdemir; Hillary H. Le; Adem Yildirim; Srivathsan V.;
    Publisher: Multidisciplinary Digital Publishing Institute

    The COVID-19 pandemic began in 2019, but it is still active. The development of an effective vaccine reduced the number of deaths; however, a treatment is still needed. Here, we aimed to inhibit viral entry to the host cell by inhibiting spike (S) protein cleavage by se...

  • publication . Other literature type . 2022
    Open Access English
    Authors:
    Schnell, Drishya Kurup; Christoph Wirblich; Leila Zabihi Diba; Rachael Lambert; Megan Watson; Noor Shaikh; Holly Ramage; Charalambos Solomides; Matthias J.;
    Publisher: Multidisciplinary Digital Publishing Institute

    Without sufficient herd immunity through either vaccination or natural infection, the coronavirus disease 2019 pandemic is unlikely to be controlled. Waning immunity with the currently approved vaccines suggests the need to evaluate vaccines causing the induction of lon...

  • publication . Other literature type . 2022
    Open Access English
    Authors:
    Xia, Shen Wang; Cheng Zhang; Bo Liang; Weiqi Wang; Na Feng; Yongkun Zhao; Tiecheng Wang; Zhendong Guo; Feihu Yan; Songtao Yang; Xianzhu;
    Publisher: Multidisciplinary Digital Publishing Institute

    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged as the prime challenge facing public health safety since 2019. Correspondingly, coronavirus disease 2019 (COVID-19) vaccines have been developed and administered worldwide, varying in design strate...

  • publication . Other literature type . 2022
    Open Access English
    Authors:
    Röst, Ferenc A. Bartha; Nóra Juhász; Sadegh Marzban; Renji Han; Gergely;
    Publisher: Multidisciplinary Digital Publishing Institute

    Paxlovid is a promising, orally bioavailable novel drug for SARS-CoV-2 with excellent safety profiles. Our main goal here is to explore the pharmacometric features of this new antiviral. To provide a detailed assessment of Paxlovid, we propose a hybrid multiscale mathem...

  • publication . Other literature type . 2022
    Open Access English
    Authors:
    Maďar, Jan Martínek; Hana Tomášková; Jaroslav Janošek; Hana Zelená; Alena Kloudová; Jakub Mrázek; Eduard Ježo; Vlastimil Král; Jitka Pohořská; Hana Šturcová; Rastislav;
    Publisher: Multidisciplinary Digital Publishing Institute

    Background and Aims: Elderly nursing home residents are especially prone to a severe course of SARS-CoV-2 infection. In this study, we aimed to investigate the complex immune response after vaccination depending on the convalescence status and vaccine. Methods: Sampling...

  • publication . Other literature type . 2022
    Open Access English
    Authors:
    Lamoth, Antonios Kritikos; Sophie Gabellon; Jean-Luc Pagani; Matteo Monti; Pierre-Yves Bochud; Oriol Manuel; Alix Coste; Gilbert Greub; Matthieu Perreau; Giuseppe Pantaleo; Antony Croxatto; Frederic;
    Publisher: Multidisciplinary Digital Publishing Institute

    Coronavirus disease 2019 (COVID-19) due to SARS-CoV-2 is associated with a wide spectrum of disease, ranging from asymptomatic infection to acute respiratory distress syndrome. Some biomarkers may predict disease severity. Among them, the anti-SARS-CoV-2 antibody respon...

  • publication . Other literature type . 2022
    Open Access English
    Authors:
    Wu, Cheng-Yang Ji; Na Han; Ye-Xiao Cheng; Jingzhe Shang; Shenghui Weng; Rong Yang; Hang-Yu Zhou; Aiping;
    Publisher: Multidisciplinary Digital Publishing Institute

    Early identification of adaptive mutations could provide timely help for the control and prevention of the COVID-19 pandemic. The fast accumulation of SARS-CoV-2 sequencing data provides important support, while also raising a great challenge for the recognition of adap...

  • publication . Other literature type . 2022
    Open Access English
    Authors:
    Streeck, Manuel Döhla; Bianca Schulte; Gero Wilbring; Beate Mareike Kümmerer; Christin Döhla; Esther Sib; Enrico Richter; Patrick Frank Ottensmeyer; Alexandra Haag; Steffen Engelhart; Anna Maria Eis-Hübinger; Martin Exner; Nico Tom Mutters; Ricarda Maria Schmithausen; Hendrik;
    Publisher: Multidisciplinary Digital Publishing Institute

    The role of environmental transmission of SARS-CoV-2 remains unclear. Thus, the aim of this study was to investigate whether viral contamination of air, wastewater, and surfaces in quarantined households result in a higher risk for exposed persons. For this study, a sou...

  • publication . Other literature type . 2022
    Open Access English
    Authors:
    Lai, Rossella Fonnesu; Venkata Bala Sai Chaitanya Thunuguntla; Ganesh Kumar Veeramachaneni; Jayakumar Singh Bondili; Veronica La Rocca; Carolina Filipponi; Pietro Giorgio Spezia; Maria Sidoti; Erika Plicanti; Paola Quaranta; Giulia Freer; Mauro Pistello; Michael Lee Mathai; Michele;
    Publisher: Multidisciplinary Digital Publishing Institute

    Lipids play a crucial role in the entry and egress of viruses, regardless of whether they are naked or enveloped. Recent evidence shows that lipid involvement in viral infection goes much further. During replication, many viruses rearrange internal lipid membranes to cr...

  • publication . Other literature type . 2022
    Open Access English
    Authors:
    Li, Bei-Guang Nan; Sen Zhang; Yu-Chang Li; Xiao-Ping Kang; Yue-Hong Chen; Lin Li; Tao Jiang; Jing;
    Publisher: Multidisciplinary Digital Publishing Institute

    The COVID-19 pandemic has frequently produced more highly transmissible SARS-CoV-2 variants, such as Omicron, which has produced sublineages. It is a challenge to tell apart high-risk Omicron sublineages and other lineages of SARS-CoV-2 variants. We aimed to build a fin...

1,634 research outcomes, page 1 of 164