As of October 2020, there is still no specific drug to treat COVID-19 as it rages worldwide. Favipiravir, indicated for the treatment of new and re-emerging influenza infections, has been suggested to be effective against SARS-CoV-2, although this is not yet fully valid...

Background: Avidity is defined as the strength of binding between immunoglobulin G (IgG) and its specific target epitope. IgG of high avidity is established during affinity maturation. Failure to achieve high avidity IgG may result in a lack of protective immunity towar...

Objective: To determine population-based estimates of coronavirus disease 2019 (COVID-19) in a densely populated urban community of Karachi, Pakistan. Methods: Three cross-sectional surveys were conducted in April, June and August 2020 in low- and high-transmission neig...

Objectives: The study aimed to assess COVID-19 impact on the morbidity and mortality of vasooclusive crisis (VOC) in sickle cell anaemia (SCA) patients. Methods: A prospective cohort study of 100 SCA patients; 50 with COVID-19 (COVID group) and 50 without (non-COVID gro...

Background: Mortuary and cemetery workers may be exposed to the bodies of people with SARS-CoV-2 infection; however, prevalence of infection among these groups is unknown. Methods: Nasopharyngeal swabs (NPS) for RT-PCR and serologic testing for SARS-CoV-2 were performed...

Objective: The World Health Organization formally announced the global COVID-19 pandemic on March 11, 2020 due to widespread infections. In this study, COVID-19 cases in India were critically analyzed during the pre-lockdown (PLD), lockdown (LD), and unlock (UL) phases....

Objective: To describe the clinical features and assess the determinants of severity and in-hospital mortality of patients with coronavirus disease 2019 (COVID-19) from a unique setting in Ethiopia. Methods: Consecutive patients admitted to a COVID-19 isolation and trea...

Background: Cardiac injury is frequently encountered in patients with coronavirus disease 2019 (COVID-19) and is associated with increased risk of mortality. Elevated troponin may signify myocardial damage and is predictive of mortality. This study aimed to assess the p...

Objectives At present, there is an absence of any proven effective anti-viral therapy for COVID-19 patients. This study aimed to assess the efficacy of intravenous immunoglobulin (IVIg) in non-severe patients with COVID-19. Methods A retrospective study based on propens...

Highlights • Course of disease dynamics is, basically, independent of age and sex. • Probability of death, hospitalization and ICU admission strongly dependent on age and sex. • Estimation of most model’s parameter requirements from large sample.