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429 research outcomes, page 1 of 43
  • publication . Article . 2021
    Open Access English
    Authors:
    Haldar, Kasturi;
    Persistent Identifiers
    Publisher: Public Library of Science (PLoS)
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  • publication . Article . 2021
    Open Access English
    Authors:
    Alexander E Gorbalenya; Stuart G Siddell;
    Persistent Identifiers
    Publisher: Public Library of Science

    Species taxa are the units of taxonomy most suited to measure virus diversity, and they account for more than 70% of all virus taxa. Yet, as evidenced by the content of GenBank entries and illustrated by the recent literature on SARS-CoV-2, they are the most neglected t...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Morgane Rolland; Peter B Gilbert;
    Persistent Identifiers
    Publisher: Public Library of Science
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  • publication . Article . 2021
    Open Access English
    Authors:
    Stange, Madlen; Mari, Alfredo; Roloff, Tim; Seth-Smith, Helena MB; Schweitzer, Michael; Brunner, Myrta; Leuzinger, Karoline; Søgaard, Kirstine K.; Gensch, Alexander; Tschudin-Sutter, Sarah; ...
    Persistent Identifiers
    Publisher: Public Library of Science (PLoS)

    The first case of SARS-CoV-2 in Basel, Switzerland was detected on February 26th 2020. We present a phylogenetic study to explore viral introduction and evolution during the exponential early phase of the local COVID-19 outbreak from February 26th until March 23rd. We s...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Hebang Yao; Hongmin Cai; Tingting Li; Bingjie Zhou; Wenming Qin; Dimitri Lavillette; Dianfan Li;
    Persistent Identifiers
    Publisher: Public Library of Science (PLoS)

    A key step to the SARS-CoV-2 infection is the attachment of its Spike receptor-binding domain (S RBD) to the host receptor ACE2. Considerable research has been devoted to the development of neutralizing antibodies, including llama-derived single-chain nanobodies, to tar...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Mokhtar R Gomaa; Amira S El Rifay; Mahmoud Shehata; Ahmed Kandeil; Mina Nabil Kamel; Mohamed A Marouf; Mohamed GabAllah; Ahmed El Taweel; Ahmed E Kayed; Omnia Kutkat; ...
    Persistent Identifiers
    Publisher: Public Library of Science

    SARS-CoV-2 virus is transmitted in closed settings to people in contact with COVID-19 patients such as healthcare workers and household contacts. However, household person-to-person transmission studies are limited. Households participating in an ongoing cohort study of...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Ju, Xiaohui; Zhu, Yunkai; Wang, Yuyan; Li, Jingrui; Zhang, Jiaxing; Gong, Mingli; Ren, Wenlin; Li, Sai; Zhong, Jin; Zhang, Linqi; ...
    Persistent Identifiers
    Publisher: Public Library of Science (PLoS)

    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the global pandemic of COVID-19. SARS-CoV-2 is classified as a biosafety level-3 (BSL-3) agent, impeding the basic research into its biology and the development of effective antivirals. Here, we develop...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Wenlin Ren; Yunkai Zhu; Yuyan Wang; Hongyang Shi; Yin Yu; Gaowei Hu; Fei Feng; Xiaomin Zhao; Jun Lan; Jianping Wu; ...
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    Publisher: Public Library of Science

    Author summary SARS-CoV-2 spike protein could bind cellular receptor ACE2 for cell entry in a species-specific manner. A diverse of mammalian ACE2 proteins could be used by SARS-CoV-2 for entry, but ACE2 proteins of koala or mouse cannot bind with viral spike protein. W...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Michael Mor; Michal Werbner; Joel Alter; Modi Safra; Elad Chomsky; Jamie C Lee; Smadar Hada-Neeman; Ksenia Polonsky; Cameron J Nowell; Alex E Clark; ...
    Persistent Identifiers
    Publisher: Public Library of Science

    Author summary The correlates of effective durable antibody response to SARS-CoV-2 infection are still unclear. In this study, we compared B cell receptor signatures in 8 Severe versus 10 Mild SARS-CoV-2 infected Israeli donors, at 1.5 months post infection using molecu...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Braun, Katarina M; Moreno, Gage K; Halfmann, Peter J; Hodcroft, Emma B.; Baker, David A; Boehm, Emma C; Weiler, Andrea M; Haj, Amelia K; Hatta, Masato; Chiba, Shiho; ...
    Persistent Identifiers
    Publisher: Public Library of Science (PLoS)

    The evolutionary mechanisms by which SARS-CoV-2 viruses adapt to mammalian hosts and, potentially, undergo antigenic evolution depend on the ways genetic variation is generated and selected within and between individual hosts. Using domestic cats as a model, we show tha...

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429 research outcomes, page 1 of 43