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37 research outcomes, page 1 of 4
  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Laura Di Domenico; Giulia Pullano; Chiara E. Sabbatini; Pierre-Yves Boëlle; Vittoria Colizza;
    Publisher: HAL CCSD
    Project: ANR | DataRedux (ANR-19-CE46-0008), EC | MOOD (874850), ANR | SPHINx (ANR-17-CE36-0008)

    As countries in Europe implement strategies to control the COVID-19 pandemic, different options are chosen regarding schools. Through a stochastic age-structured transmission model calibrated to the observed epidemic in Île-de-France in the first wave, we explored scena...

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  • publication . Article . 2021
    Open Access
    Authors:
    Moreews, Marion; Le Gouge, Kenz; Khaldi-Plassart, Samira; Pescarmona, Rémi; Mathieu, Anne-Laure; Malcus, Christophe; Djebali, Sophia; Bellomo, Alicia; Dauwalder, Olivier; Perret, Magali; ...
    Persistent Identifiers
    Publisher: American Association for the Advancement of Science (AAAS)
    Project: ANR | AIR-MI (ANR-18-ECVD-0001), EC | iReceptor Plus (825821), ANR | iMAP (ANR-16-RHUS-0001), EC | TRIPOD (322856)

    International audience; Multisystem inflammatory syndrome in children (MIS-C) is a delayed and severe complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection that strikes previously healthy children. As MIS-C combines clinical features of ...

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Loïc Berger; Nicolas Berger; Valentina Bosetti; Itzhak Gilboa; Lars Peter Hansen; Christopher I Jarvis; Massimo Marinacci; Richard Smith;
    Persistent Identifiers
    Publisher: Proceedings of the National Academy of Sciences
    Project: EC | INDIMACRO (670337), ANR | INDUCED (ANR-17-CE03-0008), ANR | ECODEC (ANR-11-LABX-0047), ANR | IPS (ANR-11-IDEX-0003), EC | RISICO (336703)

    International audience; Policymaking during a pandemic can be extremely challenging. As COVID-19 is a new disease and its global impacts are unprecedented, decisions are taken in a highly uncertain, complex, and rapidly changing environment. In such a context, in which ...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Mathieu Roche;
    Persistent Identifiers
    Project: EC | MOOD (874850), ANR | DIGITAG (ANR-16-CONV-0004)

    International audience; The vocabulary used in news on a disease such as COVID-19 changes according the period [4]. This aspect is discussed on the basis of MEDISYS-sourced media datasets via two studies. The first focuses on terminology extraction and the second on per...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Giulia Pullano; Eugenio Valdano; Nicola Scarpa; Stefania Rubrichi; Vittoria Colizza;
    Persistent Identifiers
    Publisher: Elsevier BV
    Project: EC | MOOD (874850), ANR | DataRedux (ANR-19-CE46-0008), ANR | EVALCOVID-19 (ANR-20-COVI-0007), EC | RECoVER (101003589)

    International audience; Background: On March 17, 2020, French authorities implemented a nationwide lockdown to respond to the COVID-19 epidemic and curb the surge of patients requiring critical care. Assessing the effect of lockdown on individual displacements is essent...

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  • publication . Preprint . Article . 2020
    Open Access English
    Authors:
    Peter Czuppon; Florence Débarre; Antonio Gonçalves; Olivier Tenaillon; Alan S. Perelson; Jérémie Guedj; François Blanquart;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | PolyPath (844369), ANR | TheraCoV (ANR-20-COVI-0018), ANR | TheoGeneDrive (ANR-19-CE45-0009)

    Repurposed drugs that are safe and immediately available constitute a first line of defense against new viral infections. Despite limited antiviral activity against SARS-CoV-2, several drugs are being tested as medication or as prophylaxis to prevent infection. Using a ...

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  • publication . Preprint . 2020
    Open Access English
    Authors:
    Peter Czuppon; Florence Débarre; Antonio Gonçalves; Olivier Tenaillon; Alan S. Perelson; Jeremie Guedj; François Blanquart;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | PolyPath (844369), ANR | TheraCoV (ANR-20-COVI-0018), ANR | TheoGeneDrive (ANR-19-CE45-0009)

    Abstract Repurposed drugs that are immediately available and have a good safety profile constitute a first line of defense against new viral infections. Despite a limited antiviral activity against SARS-CoV-2, several drugs serve as candidates for application, not only ...

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  • publication . Preprint . 2020
    Open Access English
    Authors:
    Federico Cocozza; Ester Piovesana; Nathalie Névo; Xavier Lahaye; Julian Buchrieser; Olivier Schwartz; Nicolas Manel; Mercedes Tkach; Clotilde Théry; Lorena Martin-Jaular;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | PSL (ANR-10-IDEX-0001), ANR | DCBIOL (ANR-11-LABX-0043), ANR | NUCLEONDRIA (ANR-19-CE15-0018), EC | TRAIN-EV (722148)

    16 SARS-CoV-2 entry is mediated by binding of the spike protein (S) to the surface 17 receptor ACE2 and subsequent priming by TMPRRS2 allowing membrane fusion. 18 Here, we produced extracellular vesicles (EVs) exposing ACE2 and demonstrate that 19 ACE2-EVs are efficient...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Ludivine Grzelak; Sarah Temmam; Cyril Planchais; Caroline Demeret; Laura Tondeur; Christèle Huon; Florence Guivel-Benhassine; Isabelle Staropoli; Maxime Chazal; Jeremy Dufloo; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | CHIKV-Viro-Immuno (ANR-14-CE14-0015), EC | RECoVER (101003589), ANR | TIMTAMDEN (ANR-14-CE14-0029)

    Different serological assays measuring anti–SARS-CoV-2 antibodies and their neutralizing activity in samples from individuals with severe and mild COVID-19 are compared.

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  • publication . Article . Review . 2020
    Open Access English
    Authors:
    Pamela McElwee; Esther Turnout; Mireille Chiroleu-Assouline; Jennifer Clapp; Cindy Isenhour; Tim Jackson; Eszter Kelemen; Daniel C. Miller; Graciela M. Rusch; Joachim H. Spangenberg; ...
    Project: ANR | PGSE (ANR-17-EURE-0001), EC | CC-LEGO (792305)

    The COVID-19 pandemic has caused unprecedented impacts to global economies, and recovery from this pandemic needs to tackle the drivers that create ecological disruptions in the first place. We discuss a number of tools across a range of actors for both short-term stimu...

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37 research outcomes, page 1 of 4