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The following results are related to COVID-19. Are you interested to view more results? Visit OpenAIRE - Explore.
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35 research outcomes, page 1 of 4
  • publication . Article . 2021
    Open Access
    Authors:
    Livia Mazzini; Donata Martinuzzi; Inesa Hyseni; Linda Benincasa; Eleonora Molesti; Elisa Casa; Giulia Lapini; Pietro Piu; Claudia Maria Trombetta; Serena Marchi; ...
    Persistent Identifiers
    Publisher: Elsevier BV
    Project: EC | EVAg (653316)

    A newly identified coronavirus, named SARS-CoV-2, emerged in December 2019 in Hubei Province, China, and quickly spread throughout the world; so far, it has caused more than 49.7 million cases of disease and 1,2 million deaths. The diagnosis of SARS-CoV-2 infection is c...

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Ceren Simsek; Victor M. Corman; Hermann Ulrich Everling; Alexander N. Lukashev; Andrea Rasche; Gael Darren Maganga; Tabea Binger; Daan Jansen; Leen Beller; Ward Deboutte; ...
    Publisher: HAL CCSD
    Project: EC | COMPARE (643476), EC | EVAg (653316), EC | PREMIUM (777657), EC | HONOURs (721367)

    ABSTRACT Bats host many viruses pathogenic to humans, and increasing evidence suggests that rotavirus A (RVA) also belongs to this list. Rotaviruses cause diarrheal disease in many mammals and birds, and their segmented genomes allow them to reassort and increase their ...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Nemanja Milisavljevic; Eva Konkolova; Jaroslav Kozak; Jan Hodek; Lucia Veselovská; Veronika Sýkorová; Karel Čížek; Radek Pohl; Luděk Eyer; Pavel Svoboda; ...
    Persistent Identifiers
    Publisher: American Chemical Society (ACS)
    Project: EC | EVAg (653316)

    A series of 7-deazaadenine ribonucleosides bearing alkyl, alkenyl, alkynyl, aryl, or hetaryl groups at position 7 as well as their 5'-O-triphosphates and two types of monophosphate prodrugs (phosphoramidates and S-acylthioethanol esters) were prepared and tested for ant...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Min Wen Ku; Maryline Bourgine; Authié P; Lopez J; Nemirov K; Moncoq F; Noirat A; Benjamin Vesin; Fabien Nevo; Catherine Blanc; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | EVAg (653316), EC | PASTEURDOC (665807)

    Highlights A lentiviral vector encoding for Spike shows preclinical efficacy as a COVID-19 vaccine. Targeting the immune response to the upper respiratory tract provides critical protection. Intranasal vaccination induces protective mucosal immunity against SARS-CoV-2 i...

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  • publication . Article . Preprint . 2020
    Open Access English
    Authors:
    Duarte Gouveia; Guylaine Miotello; Fabrice Gallais; Jean Charles Gaillard; Stéphanie Debroas; Laurent Bellanger; Jean-Philippe Lavigne; Albert Sotto; Lucia Grenga; Olivier Pible; ...
    Publisher: American Chemical Society (ACS)
    Project: EC | EVAg (653316)

    International audience; Rapid but yet sensitive, specific, and high-throughput detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in clinical samples is key to diagnose infected people and to better control the spread of the virus. Alternative...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Pauline Maisonnasse; Jeremie Guedj; Vanessa Contreras; Sylvie Behillil; Caroline Solas; Romain Marlin; Thibaut Naninck; Andrés Pizzorno; Julien Lemaitre; Antonio Gonçalves; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | IDMIT (ANR-11-INBS-0008), EC | Fight-nCoV (101003555), EC | EVAg (653316), EC | TRANSVAC2 (730964)

    International audience; Coronavirus disease 2019 (COVID-19) has rapidly become a global pandemic and no antiviral drug or vaccine is yet available for the treatment of this disease1-3. Several clinical studies are ongoing to evaluate the efficacy of repurposed drugs tha...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Simon G. P. Funnell; W. E. Dowling; César Muñoz-Fontela; Pierre Stéphane Gsell; Donald E. Ingber; G. A. Hamilton; Leen Delang; Joana Rocha-Pereira; Suzanne J. F. Kaptein; K. H. Dallmeier; ...
    Persistent Identifiers
    Publisher: Nature Publishing Group UK
    Project: EC | EVAg (653316), ANR | IDMIT (ANR-11-INBS-0008), NIH | Lung-on-a-Chip Disease Mo... (1UG3HL141797-01), EC | TRANSVAC2 (730964)

    International audience; There is an urgent need for drugs, therapies and vaccines to be available to protect the human population against COVID-19. One of the first approaches taken in the COVID-19 global response was to consider repurposing licensed drugs. This comment...

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  • publication . Other literature type . Article . 2020
    Open Access English
    Authors:
    Martina Rueca; Barbara Bartolini; Cesare E. M. Gruber; Antonio Piralla; Fausto Baldanti; Emanuela Giombini; Francesco Messina; Luisa Marchioni; Giuseppe Ippolito; Antonino Di Caro; ...
    Publisher: Multidisciplinary Digital Publishing Institute
    Project: EC | EVAg (653316), EC | EXSCALATE4CoV (101003551)

    <jats:p>We report whole-genome and intra-host variability of SARS-Cov-2 assessed by next generation sequencing (NGS) in upper (URT) and lower respiratory tract (LRT) from COVID-19 patients. The aim was to identify possible tissue-specific patterns and signatures of vari...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Allan Sauvat; Fabiola Ciccosanti; Francesca Colavita; Martina Di Rienzo; Concetta Castilletti; Maria Rosaria Capobianchi; Oliver Kepp; Laurence Zitvogel; Gian Maria Fimia; Mauro Piacentini; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | EVAg (653316), ANR | Université de Paris (ANR-18-IDEX-0001)

    <jats:title>Abstract</jats:title><jats:p>The current epidemic of coronavirus disease-19 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) calls for the development of inhibitors of viral replication. Here, we performed a bioinformatic ana...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Eva Konkolova; Milan Dejmek; Hubert Hřebabecký; Michal Šála; Jiří Böserle; Radim Nencka; Evzen Boura;
    Persistent Identifiers
    Publisher: Elsevier BV
    Project: EC | EVAg (653316)

    Remdesivir was shown to inhibit RNA-dependent RNA-polymerases (RdRp) from distinct viral families such as from Filoviridae (Ebola) and Coronaviridae (SARS-CoV, SARS-CoV-2, MERS). In this study, we tested the ability of remdesivir to inhibit RdRps from the Flaviviridae f...

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35 research outcomes, page 1 of 4