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9 research outcomes, page 1 of 1
  • publication . Research . Preprint . Other literature type . 2021
    Restricted
    Authors:
    Stéphane Pelleau; Tom Woudenberg; Jason Rosado; Françoise Donnadieu; Laura Garcia; Thomas Obadia; Soazic Gardais; Yasmine Elgharbawy; Aurelie Velay; Maria Gonzalez; ...
    Persistent Identifiers
    Project: WT | Wellcome – Health Researc... (203930), EC | MultiSeroSurv (852373), EC | SynarchiC (771813)

    <jats:title>Abstract</jats:title><jats:p>Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a complex antibody response that varies by orders of magnitude between individuals and over time. Waning antibody levels lead to reduced sensitiv...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Vallès, Xavier; Stenseth, Nils Chr.; Demeure, Christian; Horby, Peter; Mead, Paul S.; Cabanillas, Oswaldo; Ratsitorahina, Mahery; Rajerison, Minoarisoa; Andrianaivoarimanana, Voahangy; Ramasindrazana, Beza; ...
    Persistent Identifiers
    Publisher: Public Library of Science (PLoS)
    Project: WT | 2017 plague epidemic in M... (211309)

    Yersinia pestis, the bacterial causative agent of plague, remains an important threat to human health. Plague is a rodent-borne disease that has historically shown an outstanding ability to colonize and persist across different species, habitats, and environments while ...

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  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Lai, Shengjie; Johansson, Michael A.; Yin, Wenwu; Wardrop, Nicola A.; van Panhuis, Willem G.; Wesolowski, Amy; Kraemer, Moritz U. G.; Bogoch, Isaac I.; Kain, Dylain; Findlater, Aidan; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: NIH | Computational Models of I... (5U54GM088491-04), NIH | A Platform for Modeling t... (3R01LM010812-03S1), CIHR , NIH | An Approach for Estimatin... (5R01LM011965-02), WT | High resolution global ma... (204613), NIH | Chinas Integrated Program... (5U19AI051915-03), NIH | Research Training in Pedi... (5T32HD040128-15), WT | Seasonal drivers of human... (106866)

    Due to worldwide increased human mobility, air-transportation data and mathematical models have been widely used to measure risks of global dispersal of pathogens. However, the seasonal and interannual risks of pathogens importation and onward transmission from endemic ...

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  • publication . Article . 2018
    Open Access
    Authors:
    Baptiste Martin; Bruno Coutard; Théo Guez; Guido C. Paesen; Bruno Canard; Françoise Debart; Jean-Jacques Vasseur; Jonathan M. Grimes; Etienne Decroly;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: EC | AHEAD III (200835), WT | Human Genetics and Diseas... (203141), EC | SILVER (260644), WT , UKRI | A structural and function... (MR/L017709/1), WT | A mechanistic understandi... (200835)

    International audience; Mononegaviruses, such as Ebola virus, encode an L (large) protein that bears all the catalytic activities for replication/transcription and RNA capping. The C-terminal conserved region VI (CRVI) of L protein contains a K-D-K-E catalytic tetrad ty...

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  • publication . Article . Other literature type . Preprint . 2018
    Open Access
    Authors:
    Mélanie Legrand; Sophie Bachellier-Bassi; Keunsook K. Lee; Yogesh Chaudhari; Hélène Tournu; Laurence Arbogast; Helene Boyer; Murielle Chauvel; Vitor Cabral; Corinne Maufrais; ...
    Publisher: Oxford University Press (OUP)
    Project: WT | The Candida albicans ORFe... (088858), EC | FINSYSB (214004), UKRI | IMPACT OF FUNGAL ADAPTATI... (MR/M026663/1), UKRI | Pathogenesis and the cell... (G0400284)

    <jats:title>ABSTRACT</jats:title><jats:p>The advent of the genomic era has made elucidating gene function at large scale a pressing challenge. ORFeome collections, whereby almost all ORFs of a given species are cloned and can be subsequently leveraged in multiple functi...

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  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Chu, Daniel K. W.; Hui, Kenrie P. Y.; Perera, Ranawaka A. P. M.; Miguel, Eve; Niemeyer, Daniela; Zhao, Jincun; Channappanavar, Rudragouda; Dudas, Gytis; Oladipo, Jamiu O.; Traoré, Amadou; ...
    Publisher: HAL CCSD
    Project: NIH | Animal Core (5P01AI060699-10), WT | Putting genomic surveilla... (206298)

    Significance Middle East respiratory syndrome (MERS) is a zoonotic disease of global health concern, and dromedary camels are the source of human infection. Although Africa has the largest number of dromedary camels, and MERS-coronavirus (MERS-CoV) is endemic in these c...

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  • publication . Article . Other literature type . 2015
    Open Access English
    Authors:
    Paesen, Guido C.; Collet, Axelle; Sallamand, Corinne; Debart, Françoise; Vasseur, Jean-Jacques; Canard, Bruno; Decroly, Etienne; Grimes, Jonathan M.;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | SILVER (260644), UKRI | A structural and function... (MR/L017709/1), WT | Identification and functi... (075491)

    The Mononegavirales include Ebola virus, Rabies, Measles virus and human Metapneumovirus (hMPV). Here, the authors have reported the high resolution crystal structure of a domain of the large protein of hMPV, providing insight into the mRNA modifying activities of this ...

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  • publication . Article . Other literature type . 2011
    Open Access
    Authors:
    P. Martin, Darren; Biagini, Philippe; Lefeuvre, Pierre; Golden, Michael; Roumagnac, Philippe; Varsani, Arvind;
    Persistent Identifiers
    Publisher: MDPI AG
    Project: WT

    Although single stranded (ss) DNA viruses that infect humans and their domesticated animals do not generally cause major diseases, the arthropod borne ssDNA viruses of plants do, and as a result seriously constrain food production in most temperate regions of the world....

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  • publication . Other literature type . Article . 2010
    Open Access
    Authors:
    Sukupolvi-Petty, Soila; Varani, Luca; Diamond, Michael S.; Whitehead, Stephen S.; Navarro-Sanchez, Erika; MacAgno, Annalisa; Simonelli, Luca; Young, Paul R.; Beltramello, Martina; Harris, Eva; ...
    Publisher: Elsevier BV
    Project: WT , SNSF | The role of innate recept... (31003AB-126027)

    International audience; Antibodies protect against homologous Dengue virus (DENV) infection but can precipitate severe dengue by promoting heterotypic virus entry via Fcγ receptors (FcγR). We immortalized memory B cells from individuals after primary or secondary infect...

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9 research outcomes, page 1 of 1