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10 research outcomes, page 1 of 1
  • publication . Article . Preprint . 2020
    Open Access English
    Authors:
    Hongyu Miao; Qianmiao Gao; Han Feng; Chengxue Zhong; Pengwei Zhu; Liang Wu; Michael D. Swartz; Xi Luo; Stacia M. DeSantis; Dejian Lai; ...
    Persistent Identifiers
    Publisher: Frontiers Media SA
    Project: NSF | CAREER: Virus Infection a... (1758290)

    Comment: 15 pages, 15 figures, 2 tables

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  • publication . Article . Preprint . 2020
    Open Access English
    Authors:
    Daniela Calvetti; Alexander Hoover; Johnie Rose; Erkki Somersalo;
    Persistent Identifiers
    Publisher: Frontiers Media SA
    Project: NSF | Priorconditioned Krylov S... (1522334), NSF | Bayesian Inverse Problems... (1714617)

    Comment: 21 pages, 15 figures

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  • publication . Article . 2020
    Open Access English
    Authors:
    Rumi Chunara; Stephanie H. Cook;
    Persistent Identifiers
    Publisher: Frontiers Media SA
    Project: NSF | CAREER: Learning from Whe... (1845487)
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  • publication . Article . 2019
    Open Access English
    Authors:
    John E. Butler; Marek Sinkora; Gang Wang; Katerina Stepanova; Yuming Li; Xuehui Cai;
    Persistent Identifiers
    Publisher: Frontiers Media S.A.
    Project: NSF | B Cell Lymphogenesis in t... (0077237)

    Porcine reproductive and respiratory syndrome virus (PRRSV) causes immune dysregulation during the Critical Window of Immunological Development. We hypothesize that thymocyte development is altered by infected thymic antigen presenting cells (TAPCs) in the fetal/neonata...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Molly Hodul; Caroline L. Dahlberg; Peter Juo;
    Persistent Identifiers
    Publisher: Frontiers Media SA
    Project: NSF | Regulation of glutamate r... (1353862), NIH | An optogenetic behavioral... (5R21NS101534-02)

    Posttranslational modification of proteins by ubiquitin regulates synapse development and synaptic transmission. Much progress has been made investigating the role of ubiquitin ligases at the synapse, however very little is known about the deubiquitinating enzymes (DUBs...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Malik, Shahana S.; Azem-e-Zahra, Syeda; Kim, Kyung Mo; Caetano-Anollés, Gustavo; Nasir, Arshan;
    Persistent Identifiers
    Publisher: Frontiers Media S.A.
    Project: NSF | Evolutionary Genomics Col... (1132791)

    Viruses can be classified into archaeoviruses, bacterioviruses, and eukaryoviruses according to the taxonomy of the infected host. The host-constrained perception of viruses implies preference of genetic exchange between viruses and cellular organisms of their host supe...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Nasir, Arshan; Kim, Kyung Mo; Caetano-Anollés, Gustavo;
    Persistent Identifiers
    Publisher: Frontiers Media S.A.
    Project: NSF | Evolutionary Genomics Col... (1132791)

    Untangling the origin and evolution of viruses remains a challenging proposition. We recently studied the global distribution of protein domain structures in thousands of completely sequenced viral and cellular proteomes with comparative genomics, phylogenomics, and mul...

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  • publication . Article . 2016
    Open Access English
    Authors:
    Jeanne M. Fair; Martha M. Stokes; Deana Pennington; Ian H. Mendenhall;
    Persistent Identifiers
    Publisher: Frontiers Media SA
    Project: NSF | Collaborative Research: C... (1135525)

    Emerging infectious diseases (EIDs), the majority of which are zoonotic, represent a tremendous challenge for public health and biosurveillance infrastructure across the globe. Due to the complexity of zoonotic pathogens, it is essential that research and response to EI...

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  • publication . Article . 2015
    Open Access
    Authors:
    Karyna Rosario; Ryan O. Schenck; Rachel C. Harbeitner; Stephanie N. Lawler; Mya Breitbart;
    Persistent Identifiers
    Publisher: Frontiers Media SA
    Project: NSF | Collaborative Research: A... (1239976)

    Viral metagenomics has recently revealed the ubiquitous and diverse nature of single-stranded DNA (ssDNA) viruses that encode a conserved replication initiator protein (Rep) in the marine environment. Although eukaryotic circular Rep-encoding ssDNA (CRESS-DNA) viruses w...

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  • publication . Article . 2013
    Open Access
    Authors:
    Jozef J. Bujarski;
    Persistent Identifiers
    Publisher: Frontiers Media SA
    Project: NSF | Role of Subgenomic RNAs i... (0920617)

    RNA recombination is one of the driving forces of genetic variability in (+)-strand RNA viruses. Various types of RNA-RNA crossovers were described including crosses between the same or different viral RNAs or between viral and cellular RNAs. Likewise, a variety of mole...

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10 research outcomes, page 1 of 1