AbstractThe development and deployment of medical devices, along with most areas of healthcare, has been significantly impacted by the COVID-19 pandemic. This has had variable ethical implications, two of which we will focus on here. First, medical device regulations ha...

Restrictions on physical movements and in-person encounters during the COVID-19 crisis confronted many qualitative researchers with challenges in conducting and completing projects requiring face-to-face fieldwork. An exploration of engaging in what we term ‘agile rese...

Coronavirus disease 2019 (COVID-19) caused by infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an acute respiratory disease with systemic complications. Therapeutic strategies for COVID-19, including repurposing (partially) developed dr...

Pre-dating COVID-19 it was widely acknowledged that there was a loneliness epidemic and that prolonged loneliness and reduced human touch results in increased propensity to heart disease, stroke and clinical dementia. Given such statistics, and the use of isolation and ...

Abstract Trust arises from confidence in a person or confidence in the practices of an institution. Theorists argue that institutional trust depends, to varying extents on intrapersonal trust, which is trust between people who know each other. Science rests its claim to...

RaPID mRNA display was used for the discovery of antiviral cyclic peptides that potently and selectively inhibit SARS-CoV-2 Mpro. The most potent inhibitor exhibited a novel binding mode, interacting with residues across the homodimer interface.

T cells play a critical role in protection against SARS-CoV-2. Despite being highly topical, the protective role of preexisting preexisting memory CD8 + T cells, induced by prior exposure to circulating common coronavirus strains, remains less clear.