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The following results are related to COVID-19. Are you interested to view more results? Visit OpenAIRE - Explore.
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3 research outcomes, page 1 of 1
  • publication . Preprint . Article . Other literature type . 2020
    Open Access English
    Authors:
    Brandi N. Williamson; Friederike Feldmann; Benjamin Schwarz; Kimberly Meade-White; Danielle P. Porter; Jonathan Schulz; Neeltje van Doremalen; Ian Leighton; Claude Kwe Yinda; Lizzette Pérez-Pérez; ...
    Publisher: Cold Spring Harbor Laboratory

    <jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>Effective therapeutics to treat COVID-19 are urgently needed. Remdesivir is a nucleotide prodrug with in vitro and in vivo efficacy against coronaviruses. Here, we tested the efficacy ...

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  • publication . Preprint . Article . Other literature type . 2020
    Open Access English
    Authors:
    Hauke S. Hillen; Goran Kokic; Lucas Farnung; Christian Dienemann; Dimitry Tegunov; Patrick Cramer;
    Publisher: Cold Spring Harbor Laboratory
    Project: EC | TRANSREGULON (693023)

    The new coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses an RNA-dependent RNA polymerase (RdRp) for the replication of its genome and the transcription of its genes1-3. Here we present a cryo-electron microscopy structure of the SARS-CoV-2 R...

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  • publication . Preprint . Article . Other literature type . 2020
    Open Access English
    Authors:
    Bao, Linlin; Deng, Wei; Huang, Baoying; Gao, Hong; Liu, Jiangning; Ren, Lili; Wei, Qiang; Yu, Pin; Xu, Yanfeng; Qi, Feifei; ...
    Persistent Identifiers
    Publisher: Cold Spring Harbor Laboratory

    <jats:title>Abstract</jats:title><jats:p>Severe acute respiratory syndrome CoV-2 (SARS-CoV-2) caused the Corona Virus Disease 2019 (COVID-19) cases in China has become a public health emergency of international concern (PHEIC). Based on angiotensin converting enzyme 2 (...

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3 research outcomes, page 1 of 1