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26,724 research outcomes, page 1 of 2,673
  • publication . Preprint . Article . 2021
    Open Access English
    Authors:
    Nader Rahimi; Nader Rahimi;
    Publisher: Preprints
    Project: NIH | Boston University Clinica... (1UL1TR001430-01)

    Simple Summary COVID-19 pandemic continues to pose a serious threat to global public health with overwhelming worldwide socio-economic disruption. SARS-CoV-2, the viral agent of COVID-19, uses its surface glycoprotein Spike (S) for host cell attachment and entry. The em...

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  • publication . Preprint . Article . 2021
    Open Access English
    Authors:
    Dimiter Prodanov;
    Persistent Identifiers
    Publisher: Preprints

    The dramatic outbreak of the coronavirus disease 2019 (COVID-19) pandemics and its ongoing progression boosted the scientific community's interest in epidemic modeling and forecasting. The SIR (Susceptible-Infected-Removed) model is a simple mathematical model of epidem...

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  • publication . Preprint . Article . 2021
    Open Access
    Authors:
    Johanna Michael; Diana Bessa de Sousa; Justin Conway; Erick Gonzales-Labrada; Rodolphe Obeid; Julia Tevini; Thomas Felder; Birgit Hutter-Paier; Horst Zerbe; Nadine Paiement; ...
    Publisher: Cold Spring Harbor Laboratory

    <jats:title>Abstract</jats:title><jats:p>The leukotriene receptor antagonist Montelukast (MTK) is an approved medication for the treatment of asthma and allergic rhinitis. The existing marketed tablet forms of MTK exhibit inconsistent uptake and bioavailability, which p...

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Lupacchini, L.; Maggi, F.; Tomino, C.; De Dominicis, C.; Mollinari, C.; Fini, M.; Bonassi, S.; Merlo, D.; Russo, P.;
    Publisher: MDPI

    (1) Background: Nicotine is implicated in the SARS-COV-2 infection through activation of the α7-nAChR and over-expression of ACE2. Our objective was to clarify the role of nicotine in SARS-CoV-2 infection exploring its molecular and cellular activity. (2) Methods: HBEpC...

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Giovanni Bruno; Anna Panzeri; Umberto Granziol; Fabio Alivernini; Andrea Chirico; Federica Galli; Fabio Lucidi; Andrea Spoto; Giulio Vidotto; Marco Bertamini;
    Publisher: MDPI AG

    <p>Background: The Covid-19 pandemic represents a major stressor for the psychological health of people worldwide. In the UK, the Covid19-Psychological Research Consortium Study (C19PRC) launched to evaluate the psychological impact of Covid-19 in the general population...

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  • publication . Preprint . Article . 2021
    Open Access
    Authors:
    Aleksei Zarubin; Vadim Stepanov; Anton Markov; Nikita Kolesnikov; A. V. Marusin; Irina Khitrinskaya; Maria Swarovskaya; Sergey Litvinov; Natalia Ekomasova; Murat Dzhaubermezov; ...
    Publisher: Cold Spring Harbor Laboratory

    The human serine protease serine 2 TMPRSS2 is involved in the priming of proteins of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and represents a possible target for COVID-19 therapy. The TMPRSS2 gene may be co-expressed with SARS-CoV-2 cell recepto...

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Mosbah, Helena; Coupaye, Muriel; Jacques, Flavien; Tauber, Maithé; Clément, Karine; Oppert, Jean-Michel; Poitou, Christine;
    Publisher: HAL CCSD

    International audience; Background: Prader-Willi syndrome (PWS) is a neurodevelopmental disorder with hypothalamic dysfunction leading to obesity and behavioral disabilities, including eating disorders (EDs). We evaluated the effects of the COVID-19 infection and lockdo...

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  • publication . Article . Preprint . 2021
    Open Access
    Authors:
    Molnar, Tamas G.; Singletary, Andrew W.; Orosz, Gabor; Ames, Aaron D.;
    Persistent Identifiers
    Publisher: IEEE

    We introduce a methodology to guarantee safety against the spread of infectious diseases by viewing epidemiological models as control systems and by considering human interventions (such as quarantining or social distancing) as control input. We consider a generalized c...

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  • publication . Conference object . Preprint . 2021
    Open Access English
    Authors:
    Huang, Ling; Ruan, Su; Denoeux, Thierry;
    Publisher: HAL CCSD

    Computed tomography (CT) image provides useful information for radiologists to diagnose Covid-19. However, visual analysis of CT scans is time-consuming. Thus, it is necessary to develop algorithms for automatic Covid-19 detection from CT images. In this paper, we propo...

  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Piotr Długosz;
    Publisher: Elsevier BV

    <p>Objective:The article aims to show the impact of the Covid-19 pandemic on mental health of American youth. It also aims to identify factors that have an impact on the mental health maintenance of young Americans. The conducted analyses are an attempt at explaining th...

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26,724 research outcomes, page 1 of 2,673