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description Publicationkeyboard_double_arrow_right Other literature type , Article 2023 Italy, NetherlandsPublisher:Schweizerbart E. Wubben; T. Veenstra; J. Witkowski; I. Raffi; F. Hilgen; R. Bos; J. van Dijk; Y. Lathouwers; B. Spiering; L. Vennema; Z. Wang; F. Sangiorgi; A. Sluijs;handle: 11564/819294
The Miocene Climatic Optimum (MCO; ~16.9–14.7 Ma) was a relatively warm interval which interrupted the Cenozoic cooling trend and bears analogies with projected near-future climate change. Evidence for MCO warming and climatic variability is dominantly based on studies from mid- to high-latitude regions and deep ocean benthic foraminiferal oxygen isotope reconstructions, whereas studies from tropical latitudes are needed to resolve latitudinal temperature gradients and ocean nutrient cycling. Sedimentary cores retrieved at Ocean Drilling Program (ODP) Site 959 (Leg 159) in the eastern equatorial Atlantic Ocean offer a near-continuous, low-latitude record spanning the Early to Middle Miocene, but age constraints were limited. To achieve an orbitally resolved age model, we generated new calcareous nannofossil and diatom biostratigraphy as well as high-resolution bulk carbonate stable carbon (δ13C) and oxygen isotope (δ18O) ratios, magnetic susceptibility (MS), weight percent CaCO3 and mean greyscale records. We record several diagnostic biostratigraphic markers and identify the well-dated onset of the MCO, Monterey Excursion (ME), Carbon Maxima (CM) events and peak warming in the bulk carbonate isotope records. An orbital age model is realized by tuning the bulk carbonate δ13C record to eccentricity extracted from the Laskar et al. (2004) astronomical solution that is consistent with the bio- and chemostratigraphic constraints. We conclude that the studied sediment record spans the Early to Middle Miocene interval between ~18.2 and 15 Ma and includes a hiatus directly prior to the onset of MCO of maximally ~700 kyr. All records reveal dominant eccentricity- paced variability, while prominent precession and obliquity paced variability is observed between ~16.9–16.1 Ma; this interval corresponds to a node in the long ~2.4 Myr eccentricity cycle. Moreover, a major shift from bio-siliceous-dominated to carbonate-rich sediments is found across the onset of the MCO (~16.9 Ma). Both lithologies represent intervals of relatively high productivity, likely associated with upwelling. Ultimately, our high-resolution record from Site 959 can provide an important opportunity for reconstructing a tropical paleoclimate record at precession-to-eccentricity resolution during the MCO.
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You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1127/nos/2023/0749&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesbronze 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1127/nos/2023/0749&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2023 Sweden, Spain, Switzerland, NetherlandsPublisher:Elsevier BV Funded by:EC | EXPANSEEC| EXPANSEJeroen de Bont; Regina Pickford; Christofer Åström; Fabian Coloma; Konstantina Dimakopoulou; Kees de Hoogh; Dorina Ibi; Klea Katsouyanni; Erik Melén; Federica Nobile; Göran Pershagen; Åsa Persson; Evangelia Samoli; Massimo Stafoggia; Cathryn Tonne; Jelle Vlaanderen; Kathrin Wolf; Roel Vermeulen; Annette Peters; Petter Ljungman;pmid: 37598594
Introduction: The complex interplay of multiple environmental factors and cardiovascular has scarcely been studied. Within the EXPANSE project, we evaluated the association between long-term exposure to multiple environmental indices and stroke incidence across Europe. Methods: Participants from three traditional adult cohorts (Germany, Netherlands and Sweden) and four administrative cohorts (Catalonia [region Spain], Rome [city-wide], Greece and Sweden [nationwide]) were followed until incident stroke, death, migration, loss of follow-up or study end. We estimated exposures at residential addresses from different exposure domains: air pollution (nitrogen dioxide (NO2), particulate matter < 2.5 μm (PM2.5), black carbon (BC), ozone), built environment (green/blue spaces, impervious surfaces) and meteorology (seasonal mean and standard deviation of temperatures). Associations between environmental exposures and stroke were estimated in single and multiple-exposure Cox proportional hazard models, and Principal Component (PC) Analyses derived prototypes for specific exposures domains. We carried out random effects meta-analyses by cohort type. Results: In over 15 million participants, increased levels of NO2 and BC were associated with increased higher stroke incidence in both cohort types. Increased Normalized Difference Vegetation Index (NDVI) was associated with a lower stroke incidence in both cohort types, whereas an increase in impervious surface was associated with an increase in stroke incidence. The first PC of the air pollution domain (PM2.5, NO2 and BC) was associated with an increase in stroke incidence. For the built environment, higher levels of NDVI and lower levels of impervious surfaces were associated with a protective effect [%change in HR per 1 unit = -2.0 (95 %CI, -5.9;2.0) and -1.1(95 %CI, -2.0; -0.3) for traditional adult and administrative cohorts, respectively]. No clear patterns were observed for distance to blue spaces or temperature parameters. Conclusions: We observed increased HRs for stroke with exposure to PM2.5, NO2 and BC, lower levels of greenness and higher impervious surface in single and combined exposure models. Project funded by the European Union’s Horizon 2020 research and innovation programme (No 874627). Jeroen de Bont is funded by the Svenska Forskningsrådet Formas (2022-00468) and Ulla Hamberg Angeby and Lennart Angeby Foundation 2022 (2022-02870).
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routesgold 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.envint.2023.108136&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2023 Belgium, United Kingdom, Netherlands, NetherlandsPublisher:Springer Science and Business Media LLC Funded by:NWO | Perturbations of System E..., EC | DOWN2EARTH, EC | HEATNWO| Perturbations of System Earth: Reading the Past to Project the Future - A proposal to create the Netherlands Earth System Science Centre (ESSC) ,EC| DOWN2EARTH ,EC| HEATBaxter, AJ; Verschuren, D; Peterse, F; Miralles, DG; Martin-Jones, CM; Maitituerdi, A; Van Der Meeren, T; Van Daele, M; Lane, CS; Haug, GH; Olago, DO; Sinninghe Damsté, JS;AbstractAnthropogenic climate change is predicted to severely impact the global hydrological cycle1, particularly in tropical regions where agriculture-based economies depend on monsoon rainfall2. In the Horn of Africa, more frequent drought conditions in recent decades3,4 contrast with climate models projecting precipitation to increase with rising temperature5. Here we use organic geochemical climate-proxy data from the sediment record of Lake Chala (Kenya and Tanzania) to probe the stability of the link between hydroclimate and temperature over approximately the past 75,000 years, hence encompassing a sufficiently wide range of temperatures to test the ‘dry gets drier, wet gets wetter’ paradigm6 of anthropogenic climate change in the time domain. We show that the positive relationship between effective moisture and temperature in easternmost Africa during the cooler last glacial period shifted to negative around the onset of the Holocene 11,700 years ago, when the atmospheric carbon dioxide concentration exceeded 250 parts per million and mean annual temperature approached modern-day values. Thus, at that time, the budget between monsoonal precipitation and continental evaporation7 crossed a tipping point such that the positive influence of temperature on evaporation became greater than its positive influence on precipitation. Our results imply that under continued anthropogenic warming, the Horn of Africa will probably experience further drying, and they highlight the need for improved simulation of both dynamic and thermodynamic processes in the tropical hydrological cycle.
Nature arrow_drop_down Ghent University Academic BibliographyArticle . 2023Data sources: Ghent University Academic BibliographyGhent University Academic BibliographyArticle . 2023Data sources: Ghent University Academic Bibliographyadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1038/s41586-023-06272-5&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 4 citations 4 popularity Top 10% influence Average impulse Average Powered by BIP!more_vert Nature arrow_drop_down Ghent University Academic BibliographyArticle . 2023Data sources: Ghent University Academic BibliographyGhent University Academic BibliographyArticle . 2023Data sources: Ghent University Academic Bibliographyadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1038/s41586-023-06272-5&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2023 Netherlands, United KingdomPublisher:Copernicus GmbH Funded by:NWO | State and fate of Antarct...NWO| State and fate of Antarctica’s gatekeepers: a HIgh Resolution approach for Ice ShElf instability (HiRISE)E. Lambert; A. Jüling; R. S. W. van de Wal; R. S. W. van de Wal; P. R. Holland;Abstract. A major source of uncertainty in future sea level projections is the ocean-driven basal melt of Antarctic ice shelves. While ice sheet models require a kilometre-scale resolution to realistically resolve ice shelf stability and grounding line migration, global or regional 3D ocean models are computationally too expensive to produce basal melt forcing fields at this resolution on long timescales. To bridge this resolution gap, we introduce the 2D numerical model LADDIE (one-layer Antarctic model for dynamical downscaling of ice–ocean exchanges), which allows for the computationally efficient modelling of detailed basal melt fields. The model is open source and can be applied easily to different geometries or different ocean forcings. The aim of this study is threefold: to introduce the model to the community, to demonstrate its application and performance in two use cases, and to describe and interpret new basal melt patterns simulated by this model. The two use cases are the small Crosson–Dotson Ice Shelf in the warm Amundsen Sea region and the large Filchner–Ronne Ice Shelf in the cold Weddell Sea. At ice-shelf-wide scales, LADDIE reproduces observed patterns of basal melting and freezing in warm and cold environments without the need to re-tune parameters for individual ice shelves. At scales of 0.5–5 km, which are typically unresolved by 3D ocean models and poorly constrained by observations, LADDIE produces plausible basal melt patterns. Most significantly, the simulated basal melt patterns are physically consistent with the applied ice shelf topography. These patterns are governed by the topographic steering and Coriolis deflection of meltwater flows, two processes that are poorly represented in basal melt parameterisations. The kilometre-scale melt patterns simulated by LADDIE include enhanced melt rates in grounding zones and basal channels and enhanced melt or freezing in shear margins. As these regions are critical for ice shelf stability, we conclude that LADDIE can provide detailed basal melt patterns at the essential resolution that ice sheet models require. The physical consistency between the applied geometry and the simulated basal melt fields indicates that LADDIE can play a valuable role in the development of coupled ice–ocean modelling.
The Cryosphere (TC);... arrow_drop_down The Cryosphere (TC); NERC Open Research ArchiveOther literature type . Article . 2023 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routesgold 1 citations 1 popularity Average influence Average impulse Average Powered by BIP!visibility 8visibility views 8 download downloads 3 Powered bymore_vert The Cryosphere (TC);... arrow_drop_down The Cryosphere (TC); NERC Open Research ArchiveOther literature type . Article . 2023 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/tc-17-3203-2023&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2023 NetherlandsPublisher:Copernicus GmbH Nick Nortier; Michel Paardekooper; Chris Lucas; Anne Blankert; Arendjan van der Neut; Stefan Luxembourg; Agnes Mewe; Wilfried van Sark;Abstract. Alongside a transition from steerable and centralized traditional electricity generation to intermittent and more decentralized renewable electricity generation from solar panels and wind turbines, Dutch energy transition scenarios project a widespread deployment of heat pumps and electric vehicles towards 2050. While clearly contributing to the decarbonization of the Dutch energy system, these developments impose challenges regarding electricity supply-demand mismatch and grid congestion. Spatially resolved electricity demand and supply profiles are required to gain a better insight into where and when such problems are likely to occur within the different scenarios. The present paper focuses on Dutch solar energy supply and features the construction of geodatabases of scenario-specific, spatially resolved electricity generation profiles for building, land and water-bound PV. Country-level PV capacities are geographically distributed based on spatial variance in roof PV potential and availability of suitable land and water use areas. Corresponding electricity generation profiles are constructed using historical meteorological measurements, a diffuse fraction model and a anisotropic transposition model. Empirically found performance ratio profiles are applied to account for a multitude of performance loss factors, including shading, dust and inverter efficiency. In 2050, building-bound capacity is projected to show only limited overlap with both land-bound and water-bound PV capacity. On the other hand, regions with considerable water-bound PV capacity also tend to show considerable land-bound PV capacity. Compared to the present-day situation, yearly country-level PV electricity generation is projected to be a factor 18.5, 15.7, or 7.7 higher in 2050 when respectively following the Regional, National or International Steering scenarios.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/adgeo-58-199-2023&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesgold 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/adgeo-58-199-2023&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2023 Netherlands, SwitzerlandPublisher:Elsevier BV Funded by:NWO | Exposome-NL, NWO | Aspasia 2013, EC | EXPANSENWO| Exposome-NL ,NWO| Aspasia 2013 ,EC| EXPANSEFemke Bouma; Nicole AH Janssen; Joost Wesseling; Sjoerd van Ratingen; Maciek Strak; Jules Kerckhoffs; Ulrike Gehring; Wouter Hendricx; Kees de Hoogh; Roel Vermeulen; Gerard Hoek;BACKGROUND: Health implications of long-term exposure to ubiquitously present ultrafine particles (UFP) are uncertain. The aim of this study was to investigate the associations between long-term UFP exposure and natural and cause-specific mortality (including cardiovascular disease (CVD), respiratory disease, and lung cancer) in the Netherlands. METHODS: A Dutch national cohort of 10.8 million adults aged >/= 30 years was followed from 2013 until 2019. Annual average UFP concentrations were estimated at the home address at baseline, using land-use regression models based on a nationwide mobile monitoring campaign performed at the midpoint of the follow-up period. Cox proportional hazard models were applied, adjusting for individual and area-level socio-economic status covariates. Two-pollutant models with the major regulated pollutants nitrogen dioxide (NO(2)) and fine particles (PM(2)(.)(5) and PM(10)), and the health relevant combustion aerosol pollutant (elemental carbon (EC)) were assessed based on dispersion modelling. RESULTS: A total of 945,615 natural deaths occurred during 71,008,209 person-years of follow-up. The correlation of UFP concentration with other pollutants ranged from moderate (0.59 (PM(2)(.)(5))) to high (0.81 (NO(2))). We found a significant association between annual average UFP exposure and natural mortality [HR 1.012 (95 % CI 1.010-1.015), per interquartile range (IQR) (2723 particles/cm(3)) increment]. Associations were stronger for respiratory disease mortality [HR 1.022 (1.013-1.032)] and lung cancer mortality [HR 1.038 (1.028-1.048)] and weaker for CVD mortality [HR 1.005 (1.000-1.011)]. The associations of UFP with natural and lung cancer mortality attenuated but remained significant in all two-pollutant models, whereas the associations with CVD and respiratory mortality attenuated to the null. CONCLUSION: Long-term UFP exposure was associated with natural and lung cancer mortality among adults independently from other regulated air pollutants.
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For further information contact us at helpdesk@openaire.euAccess Routesgold 8 citations 8 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.envint.2023.107960&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Other literature type , Article 2023 NetherlandsPublisher:Copernicus GmbH Funded by:NWO | State and fate of Antarct...NWO| State and fate of Antarctica’s gatekeepers: a HIgh Resolution approach for Ice ShElf instability (HiRISE)Authors: Veldhuijsen, Sanne; van de Berg, Willem Jan; Brils, Max; Kuipers Munneke, Peter; +3 AuthorsVeldhuijsen, Sanne; van de Berg, Willem Jan; Brils, Max; Kuipers Munneke, Peter; van den Broeke, Michiel; Sub Dynamics Meteorology; Marine and Atmospheric Research;handle: 1874/428200
Firn simulations are essential for understanding Antarctic ice sheet mass change, as they enable us to convert satellite altimetry observed volume changes to mass changes and column thickness to ice thickness and to quantify the meltwater buffering capacity of firn. Here, we present and evaluate a simulation of the contemporary Antarctic firn layer using the updated semi-empirical IMAU Firn Densification Model (IMAU-FDM) for the period 1979–2020. We have improved previous fresh-snow density and firn compaction parameterizations and used updated atmospheric forcing. In addition, the model has been calibrated and evaluated using 112 firn core density observations across the ice sheet. We found that 62 % of the seasonal and 67 % of the decadal surface height variability are due to variations in firn air content rather than firn mass. Comparison of simulated surface elevation change with a previously published multi-mission altimetry product for the period 2003–2015 shows that performance of the updated model has improved, notably in Dronning Maud Land and Wilkes Land. However, a substantial trend difference (>10 cm yr−1) remains in the Antarctic Peninsula and Ellsworth Land, mainly caused by uncertainties in the spin-up forcing. By estimating previous climatic conditions from ice core data, these trend differences can be reduced by 38 %.
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You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routesgold 4 citations 4 popularity Top 10% influence Average impulse Average Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/tc-17-1675-2023&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2023 NetherlandsPublisher:BMJ Jason YY Wong; Batel Blechter; Bryan A Bassig; Yufei Dai; Roel Vermeulen; Wei Hu; Mohammad L Rahman; Huawei Duan; Yong Niu; George S Downward; Shuguang Leng; Bu-Tian Ji; Wei Fu; Jun Xu; Kees Meliefste; Baosen Zhou; Jufang Yang; Dianzhi Ren; Meng Ye; Xiaowei Jia; Tao Meng; Ping Bin; H. Dean Hosgood; Nathaniel Rothman; Debra T Silverman; Yuxin Zheng; Qing Lan;BackgroundWe previously found that occupational exposure to diesel engine exhaust (DEE) was associated with alterations to 19 biomarkers that potentially reflect the mechanisms of carcinogenesis. Whether DEE is associated with biological alterations at concentrations under existing or recommended occupational exposure limits (OELs) is unclear.MethodsIn a cross-sectional study of 54 factory workers exposed long-term to DEE and 55 unexposed controls, we reanalysed the 19 previously identified biomarkers. Multivariable linear regression was used to compare biomarker levels between DEE-exposed versus unexposed subjects and to assess elemental carbon (EC) exposure-response relationships, adjusted for age and smoking status. We analysed each biomarker at EC concentrations below the US Mine Safety and Health Administration (MSHA) OEL (<106 µg/m3), below the European Union (EU) OEL (<50 µg/m3) and below the American Conference of Governmental Industrial Hygienists (ACGIH) recommendation (<20 µg/m3).ResultsBelow the MSHA OEL, 17 biomarkers were altered between DEE-exposed workers and unexposed controls. Below the EU OEL, DEE-exposed workers had elevated lymphocytes (p=9E-03, false discovery rate (FDR)=0.04), CD4+ count (p=0.02, FDR=0.05), CD8+ count (p=5E-03, FDR=0.03) and miR-92a-3p (p=0.02, FDR=0.05), and nasal turbinate gene expression (first principal component: p=1E-06, FDR=2E-05), as well as decreased C-reactive protein (p=0.02, FDR=0.05), macrophage inflammatory protein-1β (p=0.04, FDR=0.09), miR-423-3p (p=0.04, FDR=0.09) and miR-122-5p (p=2E-03, FDR=0.02). Even at EC concentrations under the ACGIH recommendation, we found some evidence of exposure-response relationships for miR-423-3p (ptrend=0.01, FDR=0.19) and gene expression (ptrend=0.02, FDR=0.19).ConclusionsDEE exposure under existing or recommended OELs may be associated with biomarkers reflective of cancer-related processes, including inflammatory/immune response.
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For further information contact us at helpdesk@openaire.euAccess Routesbronze 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2023 NetherlandsPublisher:Copernicus GmbH Bijlmakers, J.; Griffioen, J.; Karssenberg, D.; Environmental Sciences; FG Landschapskunde, Gis, Hydrologie; Global Ecohydrology and Sustainability; Water Quality Management; Landdegradatie en aardobservatie; Landscape functioning, Geocomputation and Hydrology;handle: 1874/427791 , 1874/427706
Abstract. Disturbance-dependent grasslands, often associated with hydromorphological and fire dynamics, are threatened, especially in subtropical climates. In the Nepalese and Indian Terai Arc Landscape at the foot of the Himalayas, natural and cultural grasslands serve a viable role for greater one-horned rhinoceros (Rhinoceros unicornis) and for grazers that form prey of the Royal Bengal tiger (Panthera tigris). The grasslands are vulnerable to encroachment of forest. We aimed to establish the effects of environmental drivers, in particular river discharge, river channel dynamics, precipitation and forest fires, on the spatio-temporal dynamics of these grasslands. The study area is the floodplain of the eastern branch of the Karnali River and adjacent western part of Bardia National Park. We created annual time series (1993–2019) of land cover with the use of field data, remotely sensed LANDSAT imagery and a supervised classification model. Additionally, we analysed the pattern of grassland patches and aerial photographs of 1964. Between 1964 and 2019, grassland patches decreased in abundance and size due to encroachment of forest. Outside the floodplain, conversion of grassland to bare substrate coincides with extreme precipitation events. Within the floodplain, conversion of grassland to bare substrate correlates with the magnitude of the annual peak discharge of the bifurcated Karnali River. Since 2009, however, this correlation is absent due to a shift of the main discharge channel to the western branch of the Karnali River. Consequently, alluvial tall grasslands (Saccharum spontaneum dominant) have vastly expanded between 2009 and 2019. Because the hydromorphological processes in the floodplain have become more static, other sources of disturbances – local flooding of ephemeral streams, anthropogenic maintenance, grazing and fires – are more paramount to prevent encroachment of grasslands. Altogether, our findings underscore that a change in the environmental drivers impact the surface area and heterogeneity of grassland patches in the landscape, which can lead to cascading effects for the grassland-dependent megafauna.
NARCIS; Utrecht Univ... arrow_drop_down add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routesgold 2 citations 2 popularity Top 10% influence Average impulse Average Powered by BIP!more_vert NARCIS; Utrecht Univ... arrow_drop_down add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2023 Switzerland, Spain, NetherlandsPublisher:Elsevier BV Funded by:NWO | Exposome-NL, SNSF | Assessing the impact of t..., EC | EXPANSENWO| Exposome-NL ,SNSF| Assessing the impact of the urban exposome on cardio-respiratory health in a highly populated European setting ,EC| EXPANSESaucy, Apolline; Gehring, Ulrike; Olmos, Sergio; Delpierre, Cyrille; de Bont, Jeroen; Gruzieva, Olena; de Hoogh, Kees; Huss, Anke; Ljungman, Petter; Melén, Erik; Persson, Åsa; Pieterson, Inka; Tewis, Marjan; Yu, Zhebin; Vermeulen, Roel; Vlaanderen, Jelle; Tonne, Cathryn; IRAS OH Epidemiology Chemical Agents;Residential relocation is increasingly used as a natural experiment in epidemiological studies to assess the health impact of changes in environmental exposures. Since the likelihood of relocation can be influenced by individual characteristics that also influence health, studies may be biased if the predictors of relocation are not appropriately accounted for. Using data from Swedish and Dutch adults (SDPP, AMIGO), and birth cohorts (BAMSE, PIAMA), we investigated factors associated with relocation and changes in multiple environmental exposures across life stages. We used logistic regression to identify baseline predictors of moving, including sociodemographic and household characteristics, health behaviors and health. We identified exposure clusters reflecting three domains of the urban exposome (air pollution, grey surface, and socioeconomic deprivation) and conducted multinomial logistic regression to identify predictors of exposome trajectories among movers. On average, 7 % of the participants relocated each year. Before relocating, movers were consistently exposed to higher levels of air pollution than non-movers. Predictors of moving differed between the adult and birth cohorts, highlighting the importance of life stages. In the adult cohorts, moving was associated with younger age, smoking, and lower education and was independent of cardio-respiratory health indicators (hypertension, BMI, asthma, COPD). Contrary to adult cohorts, higher parental education and household socioeconomic position were associated with a higher probability of relocation in birth cohorts, alongside being the first child and living in a multi-unit dwelling. Among movers in all cohorts, those with a higher socioeconomic position at baseline were more likely to move towards healthier levels of the urban exposome. We provide new insights into predictors of relocation and subsequent changes in multiple aspects of the urban exposome in four cohorts covering different life stages in Sweden and the Netherlands. These results inform strategies to limit bias due to residential self-selection in epidemiological studies using relocation as a natural experiment. The EXPANSE project is funded by the European Union’s Horizon 2020 research and innovation programme under grand agreement No 874627. This research has received funding from the EXPOSOME-NL Gravitation program of the Dutch Ministry of Education, Culture, and Science and the Netherlands Organization for Scientific Research (NWO grant number 024.004.017). AS has received funding from the Swiss National Science Foundation (grant number 210781). We acknowledge collaborators involved in the EXPANSE project and those who participated in the cohort data collection and preparation for this research. The AMIGO cohort was funded by the Netherlands Organisation for Health Research and Development (ZonMw) within the Electromagnetic Fields and Health Research programme (grant numbers 85200001 and 85200002). The SDPP cohort was funded by the Stockholm County Council, the Swedish Research Council, the Swedish Diabetes Association, and Novo Nordisk Scandinavia. The PIAMA study was supported by The Netherlands Organization for Health Research and Development; The Dutch Research Council (NWO); The Lung Foundation Netherlands; The Netherlands Ministry of Spatial Planning, Housing, and the Environment; The Netherlands Ministry of Health, Welfare, and Sport; and The National Institute for Public Health and the Environment. The BAMSE study was supported by grants from the Swedish Research Council (2016-03086; 2020-01886), the Swedish Heart-Lung Foundation, Region Stockholm (ALF project, and for cohort and database maintenance).
NARCIS; Utrecht Univ... arrow_drop_down NARCIS; Utrecht University RepositoryArticle . 2023add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routesgold 1 citations 1 popularity Average influence Average impulse Average Powered by BIP!more_vert NARCIS; Utrecht Univ... arrow_drop_down NARCIS; Utrecht University RepositoryArticle . 2023add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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description Publicationkeyboard_double_arrow_right Other literature type , Article 2023 Italy, NetherlandsPublisher:Schweizerbart E. Wubben; T. Veenstra; J. Witkowski; I. Raffi; F. Hilgen; R. Bos; J. van Dijk; Y. Lathouwers; B. Spiering; L. Vennema; Z. Wang; F. Sangiorgi; A. Sluijs;handle: 11564/819294
The Miocene Climatic Optimum (MCO; ~16.9–14.7 Ma) was a relatively warm interval which interrupted the Cenozoic cooling trend and bears analogies with projected near-future climate change. Evidence for MCO warming and climatic variability is dominantly based on studies from mid- to high-latitude regions and deep ocean benthic foraminiferal oxygen isotope reconstructions, whereas studies from tropical latitudes are needed to resolve latitudinal temperature gradients and ocean nutrient cycling. Sedimentary cores retrieved at Ocean Drilling Program (ODP) Site 959 (Leg 159) in the eastern equatorial Atlantic Ocean offer a near-continuous, low-latitude record spanning the Early to Middle Miocene, but age constraints were limited. To achieve an orbitally resolved age model, we generated new calcareous nannofossil and diatom biostratigraphy as well as high-resolution bulk carbonate stable carbon (δ13C) and oxygen isotope (δ18O) ratios, magnetic susceptibility (MS), weight percent CaCO3 and mean greyscale records. We record several diagnostic biostratigraphic markers and identify the well-dated onset of the MCO, Monterey Excursion (ME), Carbon Maxima (CM) events and peak warming in the bulk carbonate isotope records. An orbital age model is realized by tuning the bulk carbonate δ13C record to eccentricity extracted from the Laskar et al. (2004) astronomical solution that is consistent with the bio- and chemostratigraphic constraints. We conclude that the studied sediment record spans the Early to Middle Miocene interval between ~18.2 and 15 Ma and includes a hiatus directly prior to the onset of MCO of maximally ~700 kyr. All records reveal dominant eccentricity- paced variability, while prominent precession and obliquity paced variability is observed between ~16.9–16.1 Ma; this interval corresponds to a node in the long ~2.4 Myr eccentricity cycle. Moreover, a major shift from bio-siliceous-dominated to carbonate-rich sediments is found across the onset of the MCO (~16.9 Ma). Both lithologies represent intervals of relatively high productivity, likely associated with upwelling. Ultimately, our high-resolution record from Site 959 can provide an important opportunity for reconstructing a tropical paleoclimate record at precession-to-eccentricity resolution during the MCO.
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You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routesbronze 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2023 Sweden, Spain, Switzerland, NetherlandsPublisher:Elsevier BV Funded by:EC | EXPANSEEC| EXPANSEJeroen de Bont; Regina Pickford; Christofer Åström; Fabian Coloma; Konstantina Dimakopoulou; Kees de Hoogh; Dorina Ibi; Klea Katsouyanni; Erik Melén; Federica Nobile; Göran Pershagen; Åsa Persson; Evangelia Samoli; Massimo Stafoggia; Cathryn Tonne; Jelle Vlaanderen; Kathrin Wolf; Roel Vermeulen; Annette Peters; Petter Ljungman;pmid: 37598594
Introduction: The complex interplay of multiple environmental factors and cardiovascular has scarcely been studied. Within the EXPANSE project, we evaluated the association between long-term exposure to multiple environmental indices and stroke incidence across Europe. Methods: Participants from three traditional adult cohorts (Germany, Netherlands and Sweden) and four administrative cohorts (Catalonia [region Spain], Rome [city-wide], Greece and Sweden [nationwide]) were followed until incident stroke, death, migration, loss of follow-up or study end. We estimated exposures at residential addresses from different exposure domains: air pollution (nitrogen dioxide (NO2), particulate matter < 2.5 μm (PM2.5), black carbon (BC), ozone), built environment (green/blue spaces, impervious surfaces) and meteorology (seasonal mean and standard deviation of temperatures). Associations between environmental exposures and stroke were estimated in single and multiple-exposure Cox proportional hazard models, and Principal Component (PC) Analyses derived prototypes for specific exposures domains. We carried out random effects meta-analyses by cohort type. Results: In over 15 million participants, increased levels of NO2 and BC were associated with increased higher stroke incidence in both cohort types. Increased Normalized Difference Vegetation Index (NDVI) was associated with a lower stroke incidence in both cohort types, whereas an increase in impervious surface was associated with an increase in stroke incidence. The first PC of the air pollution domain (PM2.5, NO2 and BC) was associated with an increase in stroke incidence. For the built environment, higher levels of NDVI and lower levels of impervious surfaces were associated with a protective effect [%change in HR per 1 unit = -2.0 (95 %CI, -5.9;2.0) and -1.1(95 %CI, -2.0; -0.3) for traditional adult and administrative cohorts, respectively]. No clear patterns were observed for distance to blue spaces or temperature parameters. Conclusions: We observed increased HRs for stroke with exposure to PM2.5, NO2 and BC, lower levels of greenness and higher impervious surface in single and combined exposure models. Project funded by the European Union’s Horizon 2020 research and innovation programme (No 874627). Jeroen de Bont is funded by the Svenska Forskningsrådet Formas (2022-00468) and Ulla Hamberg Angeby and Lennart Angeby Foundation 2022 (2022-02870).
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routesgold 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2023 Belgium, United Kingdom, Netherlands, NetherlandsPublisher:Springer Science and Business Media LLC Funded by:NWO | Perturbations of System E..., EC | DOWN2EARTH, EC | HEATNWO| Perturbations of System Earth: Reading the Past to Project the Future - A proposal to create the Netherlands Earth System Science Centre (ESSC) ,EC| DOWN2EARTH ,EC| HEATBaxter, AJ; Verschuren, D; Peterse, F; Miralles, DG; Martin-Jones, CM; Maitituerdi, A; Van Der Meeren, T; Van Daele, M; Lane, CS; Haug, GH; Olago, DO; Sinninghe Damsté, JS;AbstractAnthropogenic climate change is predicted to severely impact the global hydrological cycle1, particularly in tropical regions where agriculture-based economies depend on monsoon rainfall2. In the Horn of Africa, more frequent drought conditions in recent decades3,4 contrast with climate models projecting precipitation to increase with rising temperature5. Here we use organic geochemical climate-proxy data from the sediment record of Lake Chala (Kenya and Tanzania) to probe the stability of the link between hydroclimate and temperature over approximately the past 75,000 years, hence encompassing a sufficiently wide range of temperatures to test the ‘dry gets drier, wet gets wetter’ paradigm6 of anthropogenic climate change in the time domain. We show that the positive relationship between effective moisture and temperature in easternmost Africa during the cooler last glacial period shifted to negative around the onset of the Holocene 11,700 years ago, when the atmospheric carbon dioxide concentration exceeded 250 parts per million and mean annual temperature approached modern-day values. Thus, at that time, the budget between monsoonal precipitation and continental evaporation7 crossed a tipping point such that the positive influence of temperature on evaporation became greater than its positive influence on precipitation. Our results imply that under continued anthropogenic warming, the Horn of Africa will probably experience further drying, and they highlight the need for improved simulation of both dynamic and thermodynamic processes in the tropical hydrological cycle.
Nature arrow_drop_down Ghent University Academic BibliographyArticle . 2023Data sources: Ghent University Academic BibliographyGhent University Academic BibliographyArticle . 2023Data sources: Ghent University Academic Bibliographyadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 4 citations 4 popularity Top 10% influence Average impulse Average Powered by BIP!more_vert Nature arrow_drop_down Ghent University Academic BibliographyArticle . 2023Data sources: Ghent University Academic BibliographyGhent University Academic BibliographyArticle . 2023Data sources: Ghent University Academic Bibliographyadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2023 Netherlands, United KingdomPublisher:Copernicus GmbH Funded by:NWO | State and fate of Antarct...NWO| State and fate of Antarctica’s gatekeepers: a HIgh Resolution approach for Ice ShElf instability (HiRISE)E. Lambert; A. Jüling; R. S. W. van de Wal; R. S. W. van de Wal; P. R. Holland;Abstract. A major source of uncertainty in future sea level projections is the ocean-driven basal melt of Antarctic ice shelves. While ice sheet models require a kilometre-scale resolution to realistically resolve ice shelf stability and grounding line migration, global or regional 3D ocean models are computationally too expensive to produce basal melt forcing fields at this resolution on long timescales. To bridge this resolution gap, we introduce the 2D numerical model LADDIE (one-layer Antarctic model for dynamical downscaling of ice–ocean exchanges), which allows for the computationally efficient modelling of detailed basal melt fields. The model is open source and can be applied easily to different geometries or different ocean forcings. The aim of this study is threefold: to introduce the model to the community, to demonstrate its application and performance in two use cases, and to describe and interpret new basal melt patterns simulated by this model. The two use cases are the small Crosson–Dotson Ice Shelf in the warm Amundsen Sea region and the large Filchner–Ronne Ice Shelf in the cold Weddell Sea. At ice-shelf-wide scales, LADDIE reproduces observed patterns of basal melting and freezing in warm and cold environments without the need to re-tune parameters for individual ice shelves. At scales of 0.5–5 km, which are typically unresolved by 3D ocean models and poorly constrained by observations, LADDIE produces plausible basal melt patterns. Most significantly, the simulated basal melt patterns are physically consistent with the applied ice shelf topography. These patterns are governed by the topographic steering and Coriolis deflection of meltwater flows, two processes that are poorly represented in basal melt parameterisations. The kilometre-scale melt patterns simulated by LADDIE include enhanced melt rates in grounding zones and basal channels and enhanced melt or freezing in shear margins. As these regions are critical for ice shelf stability, we conclude that LADDIE can provide detailed basal melt patterns at the essential resolution that ice sheet models require. The physical consistency between the applied geometry and the simulated basal melt fields indicates that LADDIE can play a valuable role in the development of coupled ice–ocean modelling.
The Cryosphere (TC);... arrow_drop_down The Cryosphere (TC); NERC Open Research ArchiveOther literature type . Article . 2023 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routesgold 1 citations 1 popularity Average influence Average impulse Average Powered by BIP!visibility 8visibility views 8 download downloads 3 Powered bymore_vert The Cryosphere (TC);... arrow_drop_down The Cryosphere (TC); NERC Open Research ArchiveOther literature type . Article . 2023 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/tc-17-3203-2023&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2023 NetherlandsPublisher:Copernicus GmbH Nick Nortier; Michel Paardekooper; Chris Lucas; Anne Blankert; Arendjan van der Neut; Stefan Luxembourg; Agnes Mewe; Wilfried van Sark;Abstract. Alongside a transition from steerable and centralized traditional electricity generation to intermittent and more decentralized renewable electricity generation from solar panels and wind turbines, Dutch energy transition scenarios project a widespread deployment of heat pumps and electric vehicles towards 2050. While clearly contributing to the decarbonization of the Dutch energy system, these developments impose challenges regarding electricity supply-demand mismatch and grid congestion. Spatially resolved electricity demand and supply profiles are required to gain a better insight into where and when such problems are likely to occur within the different scenarios. The present paper focuses on Dutch solar energy supply and features the construction of geodatabases of scenario-specific, spatially resolved electricity generation profiles for building, land and water-bound PV. Country-level PV capacities are geographically distributed based on spatial variance in roof PV potential and availability of suitable land and water use areas. Corresponding electricity generation profiles are constructed using historical meteorological measurements, a diffuse fraction model and a anisotropic transposition model. Empirically found performance ratio profiles are applied to account for a multitude of performance loss factors, including shading, dust and inverter efficiency. In 2050, building-bound capacity is projected to show only limited overlap with both land-bound and water-bound PV capacity. On the other hand, regions with considerable water-bound PV capacity also tend to show considerable land-bound PV capacity. Compared to the present-day situation, yearly country-level PV electricity generation is projected to be a factor 18.5, 15.7, or 7.7 higher in 2050 when respectively following the Regional, National or International Steering scenarios.
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For further information contact us at helpdesk@openaire.euAccess Routesgold 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2023 Netherlands, SwitzerlandPublisher:Elsevier BV Funded by:NWO | Exposome-NL, NWO | Aspasia 2013, EC | EXPANSENWO| Exposome-NL ,NWO| Aspasia 2013 ,EC| EXPANSEFemke Bouma; Nicole AH Janssen; Joost Wesseling; Sjoerd van Ratingen; Maciek Strak; Jules Kerckhoffs; Ulrike Gehring; Wouter Hendricx; Kees de Hoogh; Roel Vermeulen; Gerard Hoek;BACKGROUND: Health implications of long-term exposure to ubiquitously present ultrafine particles (UFP) are uncertain. The aim of this study was to investigate the associations between long-term UFP exposure and natural and cause-specific mortality (including cardiovascular disease (CVD), respiratory disease, and lung cancer) in the Netherlands. METHODS: A Dutch national cohort of 10.8 million adults aged >/= 30 years was followed from 2013 until 2019. Annual average UFP concentrations were estimated at the home address at baseline, using land-use regression models based on a nationwide mobile monitoring campaign performed at the midpoint of the follow-up period. Cox proportional hazard models were applied, adjusting for individual and area-level socio-economic status covariates. Two-pollutant models with the major regulated pollutants nitrogen dioxide (NO(2)) and fine particles (PM(2)(.)(5) and PM(10)), and the health relevant combustion aerosol pollutant (elemental carbon (EC)) were assessed based on dispersion modelling. RESULTS: A total of 945,615 natural deaths occurred during 71,008,209 person-years of follow-up. The correlation of UFP concentration with other pollutants ranged from moderate (0.59 (PM(2)(.)(5))) to high (0.81 (NO(2))). We found a significant association between annual average UFP exposure and natural mortality [HR 1.012 (95 % CI 1.010-1.015), per interquartile range (IQR) (2723 particles/cm(3)) increment]. Associations were stronger for respiratory disease mortality [HR 1.022 (1.013-1.032)] and lung cancer mortality [HR 1.038 (1.028-1.048)] and weaker for CVD mortality [HR 1.005 (1.000-1.011)]. The associations of UFP with natural and lung cancer mortality attenuated but remained significant in all two-pollutant models, whereas the associations with CVD and respiratory mortality attenuated to the null. CONCLUSION: Long-term UFP exposure was associated with natural and lung cancer mortality among adults independently from other regulated air pollutants.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.envint.2023.107960&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesgold 8 citations 8 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.envint.2023.107960&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Other literature type , Article 2023 NetherlandsPublisher:Copernicus GmbH Funded by:NWO | State and fate of Antarct...NWO| State and fate of Antarctica’s gatekeepers: a HIgh Resolution approach for Ice ShElf instability (HiRISE)Authors: Veldhuijsen, Sanne; van de Berg, Willem Jan; Brils, Max; Kuipers Munneke, Peter; +3 AuthorsVeldhuijsen, Sanne; van de Berg, Willem Jan; Brils, Max; Kuipers Munneke, Peter; van den Broeke, Michiel; Sub Dynamics Meteorology; Marine and Atmospheric Research;handle: 1874/428200
Firn simulations are essential for understanding Antarctic ice sheet mass change, as they enable us to convert satellite altimetry observed volume changes to mass changes and column thickness to ice thickness and to quantify the meltwater buffering capacity of firn. Here, we present and evaluate a simulation of the contemporary Antarctic firn layer using the updated semi-empirical IMAU Firn Densification Model (IMAU-FDM) for the period 1979–2020. We have improved previous fresh-snow density and firn compaction parameterizations and used updated atmospheric forcing. In addition, the model has been calibrated and evaluated using 112 firn core density observations across the ice sheet. We found that 62 % of the seasonal and 67 % of the decadal surface height variability are due to variations in firn air content rather than firn mass. Comparison of simulated surface elevation change with a previously published multi-mission altimetry product for the period 2003–2015 shows that performance of the updated model has improved, notably in Dronning Maud Land and Wilkes Land. However, a substantial trend difference (>10 cm yr−1) remains in the Antarctic Peninsula and Ellsworth Land, mainly caused by uncertainties in the spin-up forcing. By estimating previous climatic conditions from ice core data, these trend differences can be reduced by 38 %.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/tc-17-1675-2023&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesgold 4 citations 4 popularity Top 10% influence Average impulse Average Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/tc-17-1675-2023&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2023 NetherlandsPublisher:BMJ Jason YY Wong; Batel Blechter; Bryan A Bassig; Yufei Dai; Roel Vermeulen; Wei Hu; Mohammad L Rahman; Huawei Duan; Yong Niu; George S Downward; Shuguang Leng; Bu-Tian Ji; Wei Fu; Jun Xu; Kees Meliefste; Baosen Zhou; Jufang Yang; Dianzhi Ren; Meng Ye; Xiaowei Jia; Tao Meng; Ping Bin; H. Dean Hosgood; Nathaniel Rothman; Debra T Silverman; Yuxin Zheng; Qing Lan;BackgroundWe previously found that occupational exposure to diesel engine exhaust (DEE) was associated with alterations to 19 biomarkers that potentially reflect the mechanisms of carcinogenesis. Whether DEE is associated with biological alterations at concentrations under existing or recommended occupational exposure limits (OELs) is unclear.MethodsIn a cross-sectional study of 54 factory workers exposed long-term to DEE and 55 unexposed controls, we reanalysed the 19 previously identified biomarkers. Multivariable linear regression was used to compare biomarker levels between DEE-exposed versus unexposed subjects and to assess elemental carbon (EC) exposure-response relationships, adjusted for age and smoking status. We analysed each biomarker at EC concentrations below the US Mine Safety and Health Administration (MSHA) OEL (<106 µg/m3), below the European Union (EU) OEL (<50 µg/m3) and below the American Conference of Governmental Industrial Hygienists (ACGIH) recommendation (<20 µg/m3).ResultsBelow the MSHA OEL, 17 biomarkers were altered between DEE-exposed workers and unexposed controls. Below the EU OEL, DEE-exposed workers had elevated lymphocytes (p=9E-03, false discovery rate (FDR)=0.04), CD4+ count (p=0.02, FDR=0.05), CD8+ count (p=5E-03, FDR=0.03) and miR-92a-3p (p=0.02, FDR=0.05), and nasal turbinate gene expression (first principal component: p=1E-06, FDR=2E-05), as well as decreased C-reactive protein (p=0.02, FDR=0.05), macrophage inflammatory protein-1β (p=0.04, FDR=0.09), miR-423-3p (p=0.04, FDR=0.09) and miR-122-5p (p=2E-03, FDR=0.02). Even at EC concentrations under the ACGIH recommendation, we found some evidence of exposure-response relationships for miR-423-3p (ptrend=0.01, FDR=0.19) and gene expression (ptrend=0.02, FDR=0.19).ConclusionsDEE exposure under existing or recommended OELs may be associated with biomarkers reflective of cancer-related processes, including inflammatory/immune response.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1136/oemed-2022-108719&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesbronze 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1136/oemed-2022-108719&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2023 NetherlandsPublisher:Copernicus GmbH Bijlmakers, J.; Griffioen, J.; Karssenberg, D.; Environmental Sciences; FG Landschapskunde, Gis, Hydrologie; Global Ecohydrology and Sustainability; Water Quality Management; Landdegradatie en aardobservatie; Landscape functioning, Geocomputation and Hydrology;handle: 1874/427791 , 1874/427706
Abstract. Disturbance-dependent grasslands, often associated with hydromorphological and fire dynamics, are threatened, especially in subtropical climates. In the Nepalese and Indian Terai Arc Landscape at the foot of the Himalayas, natural and cultural grasslands serve a viable role for greater one-horned rhinoceros (Rhinoceros unicornis) and for grazers that form prey of the Royal Bengal tiger (Panthera tigris). The grasslands are vulnerable to encroachment of forest. We aimed to establish the effects of environmental drivers, in particular river discharge, river channel dynamics, precipitation and forest fires, on the spatio-temporal dynamics of these grasslands. The study area is the floodplain of the eastern branch of the Karnali River and adjacent western part of Bardia National Park. We created annual time series (1993–2019) of land cover with the use of field data, remotely sensed LANDSAT imagery and a supervised classification model. Additionally, we analysed the pattern of grassland patches and aerial photographs of 1964. Between 1964 and 2019, grassland patches decreased in abundance and size due to encroachment of forest. Outside the floodplain, conversion of grassland to bare substrate coincides with extreme precipitation events. Within the floodplain, conversion of grassland to bare substrate correlates with the magnitude of the annual peak discharge of the bifurcated Karnali River. Since 2009, however, this correlation is absent due to a shift of the main discharge channel to the western branch of the Karnali River. Consequently, alluvial tall grasslands (Saccharum spontaneum dominant) have vastly expanded between 2009 and 2019. Because the hydromorphological processes in the floodplain have become more static, other sources of disturbances – local flooding of ephemeral streams, anthropogenic maintenance, grazing and fires – are more paramount to prevent encroachment of grasslands. Altogether, our findings underscore that a change in the environmental drivers impact the surface area and heterogeneity of grassland patches in the landscape, which can lead to cascading effects for the grassland-dependent megafauna.
NARCIS; Utrecht Univ... arrow_drop_down add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/bg-20-1113-2023&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesgold 2 citations 2 popularity Top 10% influence Average impulse Average Powered by BIP!more_vert NARCIS; Utrecht Univ... arrow_drop_down add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/bg-20-1113-2023&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2023 Switzerland, Spain, NetherlandsPublisher:Elsevier BV Funded by:NWO | Exposome-NL, SNSF | Assessing the impact of t..., EC | EXPANSENWO| Exposome-NL ,SNSF| Assessing the impact of the urban exposome on cardio-respiratory health in a highly populated European setting ,EC| EXPANSESaucy, Apolline; Gehring, Ulrike; Olmos, Sergio; Delpierre, Cyrille; de Bont, Jeroen; Gruzieva, Olena; de Hoogh, Kees; Huss, Anke; Ljungman, Petter; Melén, Erik; Persson, Åsa; Pieterson, Inka; Tewis, Marjan; Yu, Zhebin; Vermeulen, Roel; Vlaanderen, Jelle; Tonne, Cathryn; IRAS OH Epidemiology Chemical Agents;Residential relocation is increasingly used as a natural experiment in epidemiological studies to assess the health impact of changes in environmental exposures. Since the likelihood of relocation can be influenced by individual characteristics that also influence health, studies may be biased if the predictors of relocation are not appropriately accounted for. Using data from Swedish and Dutch adults (SDPP, AMIGO), and birth cohorts (BAMSE, PIAMA), we investigated factors associated with relocation and changes in multiple environmental exposures across life stages. We used logistic regression to identify baseline predictors of moving, including sociodemographic and household characteristics, health behaviors and health. We identified exposure clusters reflecting three domains of the urban exposome (air pollution, grey surface, and socioeconomic deprivation) and conducted multinomial logistic regression to identify predictors of exposome trajectories among movers. On average, 7 % of the participants relocated each year. Before relocating, movers were consistently exposed to higher levels of air pollution than non-movers. Predictors of moving differed between the adult and birth cohorts, highlighting the importance of life stages. In the adult cohorts, moving was associated with younger age, smoking, and lower education and was independent of cardio-respiratory health indicators (hypertension, BMI, asthma, COPD). Contrary to adult cohorts, higher parental education and household socioeconomic position were associated with a higher probability of relocation in birth cohorts, alongside being the first child and living in a multi-unit dwelling. Among movers in all cohorts, those with a higher socioeconomic position at baseline were more likely to move towards healthier levels of the urban exposome. We provide new insights into predictors of relocation and subsequent changes in multiple aspects of the urban exposome in four cohorts covering different life stages in Sweden and the Netherlands. These results inform strategies to limit bias due to residential self-selection in epidemiological studies using relocation as a natural experiment. The EXPANSE project is funded by the European Union’s Horizon 2020 research and innovation programme under grand agreement No 874627. This research has received funding from the EXPOSOME-NL Gravitation program of the Dutch Ministry of Education, Culture, and Science and the Netherlands Organization for Scientific Research (NWO grant number 024.004.017). AS has received funding from the Swiss National Science Foundation (grant number 210781). We acknowledge collaborators involved in the EXPANSE project and those who participated in the cohort data collection and preparation for this research. The AMIGO cohort was funded by the Netherlands Organisation for Health Research and Development (ZonMw) within the Electromagnetic Fields and Health Research programme (grant numbers 85200001 and 85200002). The SDPP cohort was funded by the Stockholm County Council, the Swedish Research Council, the Swedish Diabetes Association, and Novo Nordisk Scandinavia. The PIAMA study was supported by The Netherlands Organization for Health Research and Development; The Dutch Research Council (NWO); The Lung Foundation Netherlands; The Netherlands Ministry of Spatial Planning, Housing, and the Environment; The Netherlands Ministry of Health, Welfare, and Sport; and The National Institute for Public Health and the Environment. The BAMSE study was supported by grants from the Swedish Research Council (2016-03086; 2020-01886), the Swedish Heart-Lung Foundation, Region Stockholm (ALF project, and for cohort and database maintenance).
NARCIS; Utrecht Univ... arrow_drop_down NARCIS; Utrecht University RepositoryArticle . 2023add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routesgold 1 citations 1 popularity Average influence Average impulse Average Powered by BIP!more_vert NARCIS; Utrecht Univ... arrow_drop_down NARCIS; Utrecht University RepositoryArticle . 2023add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.envint.2023.107849&type=result"></script>'); --> </script>
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