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2 Research products, page 1 of 1

  • COVID-19
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  • Open Access Turkish
    Authors: 
    Yıldız, Muhammet Çağrı;
    Publisher: Bursa Uludağ Üniversitesi
    Country: Turkey

    Bu çalışma, Türkiye Cumhuriyeti Sağlık Bakanlığı olası COVID-19 vaka sorgulama kılavuzuna göre; kombine nazofaringeal/orofaringeal sürüntü örneklerinde RT-PCR ile hızlı antijen test sonuçlarının karşılaştırılması amacıyla yapıldı. Çalışmada, 28 Ekim 2021-14 Kasım 2021 tarihleri arasında, Bursa Uludağ Üniveristesi Sağlık Uygulama ve Araştırma Merkezi Acil Pandemi Polikliniğine, SARS-CoV-2 RT-PCR testi (Biospeedy, Bioeksen, İstanbul, Turkiye) yaptırmak için başvurmuş olan 200 hastadan kombine nazofaringeal/orofaringeal (kombine burun boğaz sürüntüsü) sürüntü örnekleri alındı. Semptomları bir haftadan kısa sürenler çalışmaya dahil edildi. Bursa Uludağ Üniversitesi Sağlık Uygulama ve Araştırma Merkezi Tıbbi Mikrobiyoloji Anabilim dalı içindeki PCR laboratuvarında Mö-screen korona antijen testleri (möLab, QIAGEN, Almanya) çalışıldı ve SARS-CoV-2 RT-PCR testi Ct değeri (döngü eşiği) ile hızlı antijen test sonuçları arasındaki uyum karşılaştırıldı. Hızlı antijen test sonuçları pozitif ya da negatif olarak kaydedildi. Pozitif sonuçlar, test bandındaki renk yoğunluğuna göre güçlü, orta, zayıf olarak tecrübeli, tek kişi tarafından değerlendirildi. İki yüz katılımcının seksen tanesinin her iki testi pozitifti. Yüz yirmisinin negatifti. Duyarlılık (80/80) ve özgüllük (120/120) %100 olarak bulundu. Zayıf pozitif olarak değerlendirilen 19 sonucun Ct değer aralığı 18,9-30,37, orta pozitif olarak değerlendirilen 38 sonucun Ct değer aralığı 16,56-28,48, güçlü pozitif olarak değerlendirilen 23 sonucun Ct değer aralığı 14,03-23,66 olarak bulundu. Ct değerleriyle hızlı antijen testinin pozitifliği arasında, istatistiksel olarak anlamlı, ters bir korelasyon bulundu (r değeri - 0,706, p < 0,001). Sonuç olarak SARS-CoV-2 PCR testi ile Mö-screen korona antijen testinin uyumunun yüksek olması nedeniyle; okullar, bakım evleri gibi kalabalık alanlarda, NAAT’ların kısıtlı olduğu veya bulunmadığı yerlerde Mö-screen korona antijen testi kullanımının uygun olduğu değerlendirildi. This study was conducted in accordance with the possible COVID-19 case investigation guidelines of the Ministry of Health of the Republic of Turkey; in order to compare the rapid antigen test results with RT-PCR in combined nasopharyngeal/oropharyngeal swab samples. In the study, combined nasopharyngeal/oropharyngeal swab samples were obtained from 200 patients who applied to Bursa Uludağ University Health Application and Research Center Emergency Pandemic Outpatient Clinic between October 28, 2021 and November 14, 2021 for the SARS-CoV-2 RT-PCR test (Biospeedy, Bioeksen, Istanbul, Turkey). Whose symptoms lasted less than a week were included in the study. Bursa Uludağ University Health Application and Research Center, Medical Microbiology PCR laboratory performed Mo-screen Corona antigen tests (moLab, QIAGEN, Germany) and SARS-CoV-2 RT-PCR test and the Ct values (cycle threshold) were determined. Antigen test results were compared with RT-PCR. Rapid antigen test results were recorded as positive or negative. The positive results were evaluated by a single experienced person as strong, medium and weak according to the color intensity in the test band. Eighty of the two hundred participants had both tests positive. One hundred and twenty of them were negative in both tests. Sensitivity (80/80) and specificity (120/120) were found to be 100%. The Ct value range of 19 results evaluated as weakly positive was 18,9-30,37, the Ct value range of 38 results evaluated as moderately positive was 16,56-28,48, and the Ct value range of 23 results considered as high positive was 14,03-23,66. A statistically significant inverse correlation was found between Ct values and the positive intensity of the rapid antigen test (r value -0,706, p < 0,001). In conclusion, due to the high compatibility of the SARS-CoV-2 PCR test and the Mö-screen corona antigen test, Mö-screen corona antigen test is usable in crowded areas such as schools, and nursing homes, and where NAAT tests are limited or unavailable.

  • Open Access Turkish
    Authors: 
    Cevizci, Tuba Özdemir;
    Publisher: Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi
    Country: Turkey

    COVID-19 is a disease that started as a pneumonia epidemic in Wuhan, China's Hubei province in January 2020, and quickly became a global health problem. There are also pregnant women in the affected group. It is well known that pregnant women are vulnerable to infections. Both pregnant women and newborns should be considered at risk for COVID19. In some studies, vertical transition is mentioned. Therefore, it is crucial to understand the impact of COVID-19 on morbidity, mortality, perinatal, maternal and fetal aspects of pregnant women and newborns in order to develop strategies for prevention and infection control. The aim of this study is to investigate the infants of mothers who had COVID-19 infection during pregnancy have cardiac effects. In this study, babies of mothers who applied to NE University Meram Medical Faculty Pediatric Cardiology and Neonatal Department between 2021-2022 and diagnosed with COVID-19 during pregnancy were evaluated cardiologically. Physical examination, heart sounds, ECO (echocardiografi) and ECG (electrocardiografi) parameters were evaluated at admission. Statistical analysis of the data was performed using the SPSS 27.0 package program (IBM SPSS, Chicago, IL, USA). Statistically, cases where p was less than 0.05 were considered significant. 41.9% (n=13) of 31 infants born to mothers who had COVID-19 infection during pregnancy were girls and 58.1% (n=18) was boys. 56.3% (n=18) of 32 babies born to vii mothers who did not have COVID-19 infection during pregnancy were girls and 43.8% (n=14) were boys. There was no significant difference between the groups in terms of gender (p=0.256). 25.8% (n=8) of the babies of mothers who had COVID-19 during pregnancy were premature, 74.2% (n=23) were mature; 15.6% (n=5) of the babies of mothers who did not have COVID-19 during pregnancy were premature and 84.4% (n=27) were mature. There was no statistically significant difference between the birth week of the babies and the status of having COVID-19 during the pregnancy of the mothers (p=0.318). There was no difference between the presence of symptoms in the newborn period and hospitalization in the intensive care unit in the newborn period and the situation of the mothers having COVID19 infection during pregnancy. There was no difference between the groups in terms of birth weight of the babies (p=0.896). There was no statistically significant difference between the weight gain rates of the babies (p=0.123). There was no significant difference between the length of stay of the babies in the intensive care unit and the status of the mothers having COVID-19 infection during their pregnancies. The values of the parameters measured in ECHO were found to be similar in babies of mothers who had and did not have COVID-19 during pregnancy (p>0.05). There was a statistically significant difference between the maximum values of the P wave measured in the ECGs of babies born to mothers with and without COVID-19 positivity (p=0.048). It was found that the other values measured on the ECG were similar in both groups, there was no statistically significant difference between them (p>0.05). Data on intrauterine exposure to COVID-19 and vertical transmission are still insufficient. In the literature review, we could not find sufficient data about the babies of mothers who had COVID-19 during pregnancy. Therefore, further studies are needed. However, no intrauterine cardiac involvement was found in our study. Coronavirüs hastalığı 2019 (COVID-19), Ocak 2020'de Çin'in Hubei eyaleti Wuhan'da pnömoni salgını şeklinde başlayıp hızlı şekilde küresel sağlık sorunu haline gelen bir hastalıktır. Hamile kadınların enfeksiyonlara karşı savunmasız oldukları iyi bilinmektedir. Hem hamile kadınlar hem de yeni doğanlar COVID-19 açısından risk altında kabul edilmelidir. Bazı çalışmalarda dikey geçişten söz edilmektedir. Bu nedenle, önleme ve enfeksiyon kontrolüne yönelik stratejiler geliştirmek için COVID-19'un morbidite, mortalite, perinatal, maternal ve fetal açıdan hamile kadınlar ve yenidoğanlar üzerindeki etkisini anlamak çok önemlidir. Bu çalışma ile gebeliğinde COVID-19 enfeksiyonu geçiren anne bebeklerinin kardiyak etkilenmesinin olup olmadığının araştırılması amaçlanmaktadır. Bu çalışmada, 2021-2022 yılları arasında Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi Çocuk Kardiyoloji ve Neonatoloji Bilim Dalı'na başvuran, gebelikte COVID-19 tanısı alan anne bebekleri kardiyolojik olarak değerlendirilmiştir. Başvuruda fizik muayene, kalp sesleri, ekokardiyografi (EKO) ve elektrokardiyografi (EKG) parametreleri değerlendirildi. Verilerin istatistiksel analizi, SPSS 27,0 paket programı (IBM SPSS, Chicago, IL, USA) kullanılarak yapıldı. İstatistiksel olarak p0,05). COVID-19 geçiren ve geçirmeyen anneden doğan bebeklerin EKG’lerinde ölçülen P dalgasının maksimum değerleri arasında istatistiksel olarak anlamlı fark vardı (p=0,048). EKG’de ölçülen diğer değerlerin her iki grupta benzer olduğu, aralarında istatistiksel olarak anlamlı fark olmadığı tespit edildi (p>0,05). İntrauterin COVID-19 maruziyeti ve dikey geçişle ilgili veriler hala yetersizdir. Literatür taramasında gebeliğinde COVID-19 geçiren anne bebekleri ile ilgili yeterli veriye rastlayamadık. Bu nedenle daha çok çalışmaya ihtiyaç vardır. Ancak çalışmamızda intrauterin kardiyak etkilenmeye rastlanmadı

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Advanced search in Research products
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The following results are related to COVID-19. Are you interested to view more results? Visit OpenAIRE - Explore.
2 Research products, page 1 of 1
  • Open Access Turkish
    Authors: 
    Yıldız, Muhammet Çağrı;
    Publisher: Bursa Uludağ Üniversitesi
    Country: Turkey

    Bu çalışma, Türkiye Cumhuriyeti Sağlık Bakanlığı olası COVID-19 vaka sorgulama kılavuzuna göre; kombine nazofaringeal/orofaringeal sürüntü örneklerinde RT-PCR ile hızlı antijen test sonuçlarının karşılaştırılması amacıyla yapıldı. Çalışmada, 28 Ekim 2021-14 Kasım 2021 tarihleri arasında, Bursa Uludağ Üniveristesi Sağlık Uygulama ve Araştırma Merkezi Acil Pandemi Polikliniğine, SARS-CoV-2 RT-PCR testi (Biospeedy, Bioeksen, İstanbul, Turkiye) yaptırmak için başvurmuş olan 200 hastadan kombine nazofaringeal/orofaringeal (kombine burun boğaz sürüntüsü) sürüntü örnekleri alındı. Semptomları bir haftadan kısa sürenler çalışmaya dahil edildi. Bursa Uludağ Üniversitesi Sağlık Uygulama ve Araştırma Merkezi Tıbbi Mikrobiyoloji Anabilim dalı içindeki PCR laboratuvarında Mö-screen korona antijen testleri (möLab, QIAGEN, Almanya) çalışıldı ve SARS-CoV-2 RT-PCR testi Ct değeri (döngü eşiği) ile hızlı antijen test sonuçları arasındaki uyum karşılaştırıldı. Hızlı antijen test sonuçları pozitif ya da negatif olarak kaydedildi. Pozitif sonuçlar, test bandındaki renk yoğunluğuna göre güçlü, orta, zayıf olarak tecrübeli, tek kişi tarafından değerlendirildi. İki yüz katılımcının seksen tanesinin her iki testi pozitifti. Yüz yirmisinin negatifti. Duyarlılık (80/80) ve özgüllük (120/120) %100 olarak bulundu. Zayıf pozitif olarak değerlendirilen 19 sonucun Ct değer aralığı 18,9-30,37, orta pozitif olarak değerlendirilen 38 sonucun Ct değer aralığı 16,56-28,48, güçlü pozitif olarak değerlendirilen 23 sonucun Ct değer aralığı 14,03-23,66 olarak bulundu. Ct değerleriyle hızlı antijen testinin pozitifliği arasında, istatistiksel olarak anlamlı, ters bir korelasyon bulundu (r değeri - 0,706, p < 0,001). Sonuç olarak SARS-CoV-2 PCR testi ile Mö-screen korona antijen testinin uyumunun yüksek olması nedeniyle; okullar, bakım evleri gibi kalabalık alanlarda, NAAT’ların kısıtlı olduğu veya bulunmadığı yerlerde Mö-screen korona antijen testi kullanımının uygun olduğu değerlendirildi. This study was conducted in accordance with the possible COVID-19 case investigation guidelines of the Ministry of Health of the Republic of Turkey; in order to compare the rapid antigen test results with RT-PCR in combined nasopharyngeal/oropharyngeal swab samples. In the study, combined nasopharyngeal/oropharyngeal swab samples were obtained from 200 patients who applied to Bursa Uludağ University Health Application and Research Center Emergency Pandemic Outpatient Clinic between October 28, 2021 and November 14, 2021 for the SARS-CoV-2 RT-PCR test (Biospeedy, Bioeksen, Istanbul, Turkey). Whose symptoms lasted less than a week were included in the study. Bursa Uludağ University Health Application and Research Center, Medical Microbiology PCR laboratory performed Mo-screen Corona antigen tests (moLab, QIAGEN, Germany) and SARS-CoV-2 RT-PCR test and the Ct values (cycle threshold) were determined. Antigen test results were compared with RT-PCR. Rapid antigen test results were recorded as positive or negative. The positive results were evaluated by a single experienced person as strong, medium and weak according to the color intensity in the test band. Eighty of the two hundred participants had both tests positive. One hundred and twenty of them were negative in both tests. Sensitivity (80/80) and specificity (120/120) were found to be 100%. The Ct value range of 19 results evaluated as weakly positive was 18,9-30,37, the Ct value range of 38 results evaluated as moderately positive was 16,56-28,48, and the Ct value range of 23 results considered as high positive was 14,03-23,66. A statistically significant inverse correlation was found between Ct values and the positive intensity of the rapid antigen test (r value -0,706, p < 0,001). In conclusion, due to the high compatibility of the SARS-CoV-2 PCR test and the Mö-screen corona antigen test, Mö-screen corona antigen test is usable in crowded areas such as schools, and nursing homes, and where NAAT tests are limited or unavailable.

  • Open Access Turkish
    Authors: 
    Cevizci, Tuba Özdemir;
    Publisher: Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi
    Country: Turkey

    COVID-19 is a disease that started as a pneumonia epidemic in Wuhan, China's Hubei province in January 2020, and quickly became a global health problem. There are also pregnant women in the affected group. It is well known that pregnant women are vulnerable to infections. Both pregnant women and newborns should be considered at risk for COVID19. In some studies, vertical transition is mentioned. Therefore, it is crucial to understand the impact of COVID-19 on morbidity, mortality, perinatal, maternal and fetal aspects of pregnant women and newborns in order to develop strategies for prevention and infection control. The aim of this study is to investigate the infants of mothers who had COVID-19 infection during pregnancy have cardiac effects. In this study, babies of mothers who applied to NE University Meram Medical Faculty Pediatric Cardiology and Neonatal Department between 2021-2022 and diagnosed with COVID-19 during pregnancy were evaluated cardiologically. Physical examination, heart sounds, ECO (echocardiografi) and ECG (electrocardiografi) parameters were evaluated at admission. Statistical analysis of the data was performed using the SPSS 27.0 package program (IBM SPSS, Chicago, IL, USA). Statistically, cases where p was less than 0.05 were considered significant. 41.9% (n=13) of 31 infants born to mothers who had COVID-19 infection during pregnancy were girls and 58.1% (n=18) was boys. 56.3% (n=18) of 32 babies born to vii mothers who did not have COVID-19 infection during pregnancy were girls and 43.8% (n=14) were boys. There was no significant difference between the groups in terms of gender (p=0.256). 25.8% (n=8) of the babies of mothers who had COVID-19 during pregnancy were premature, 74.2% (n=23) were mature; 15.6% (n=5) of the babies of mothers who did not have COVID-19 during pregnancy were premature and 84.4% (n=27) were mature. There was no statistically significant difference between the birth week of the babies and the status of having COVID-19 during the pregnancy of the mothers (p=0.318). There was no difference between the presence of symptoms in the newborn period and hospitalization in the intensive care unit in the newborn period and the situation of the mothers having COVID19 infection during pregnancy. There was no difference between the groups in terms of birth weight of the babies (p=0.896). There was no statistically significant difference between the weight gain rates of the babies (p=0.123). There was no significant difference between the length of stay of the babies in the intensive care unit and the status of the mothers having COVID-19 infection during their pregnancies. The values of the parameters measured in ECHO were found to be similar in babies of mothers who had and did not have COVID-19 during pregnancy (p>0.05). There was a statistically significant difference between the maximum values of the P wave measured in the ECGs of babies born to mothers with and without COVID-19 positivity (p=0.048). It was found that the other values measured on the ECG were similar in both groups, there was no statistically significant difference between them (p>0.05). Data on intrauterine exposure to COVID-19 and vertical transmission are still insufficient. In the literature review, we could not find sufficient data about the babies of mothers who had COVID-19 during pregnancy. Therefore, further studies are needed. However, no intrauterine cardiac involvement was found in our study. Coronavirüs hastalığı 2019 (COVID-19), Ocak 2020'de Çin'in Hubei eyaleti Wuhan'da pnömoni salgını şeklinde başlayıp hızlı şekilde küresel sağlık sorunu haline gelen bir hastalıktır. Hamile kadınların enfeksiyonlara karşı savunmasız oldukları iyi bilinmektedir. Hem hamile kadınlar hem de yeni doğanlar COVID-19 açısından risk altında kabul edilmelidir. Bazı çalışmalarda dikey geçişten söz edilmektedir. Bu nedenle, önleme ve enfeksiyon kontrolüne yönelik stratejiler geliştirmek için COVID-19'un morbidite, mortalite, perinatal, maternal ve fetal açıdan hamile kadınlar ve yenidoğanlar üzerindeki etkisini anlamak çok önemlidir. Bu çalışma ile gebeliğinde COVID-19 enfeksiyonu geçiren anne bebeklerinin kardiyak etkilenmesinin olup olmadığının araştırılması amaçlanmaktadır. Bu çalışmada, 2021-2022 yılları arasında Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi Çocuk Kardiyoloji ve Neonatoloji Bilim Dalı'na başvuran, gebelikte COVID-19 tanısı alan anne bebekleri kardiyolojik olarak değerlendirilmiştir. Başvuruda fizik muayene, kalp sesleri, ekokardiyografi (EKO) ve elektrokardiyografi (EKG) parametreleri değerlendirildi. Verilerin istatistiksel analizi, SPSS 27,0 paket programı (IBM SPSS, Chicago, IL, USA) kullanılarak yapıldı. İstatistiksel olarak p0,05). COVID-19 geçiren ve geçirmeyen anneden doğan bebeklerin EKG’lerinde ölçülen P dalgasının maksimum değerleri arasında istatistiksel olarak anlamlı fark vardı (p=0,048). EKG’de ölçülen diğer değerlerin her iki grupta benzer olduğu, aralarında istatistiksel olarak anlamlı fark olmadığı tespit edildi (p>0,05). İntrauterin COVID-19 maruziyeti ve dikey geçişle ilgili veriler hala yetersizdir. Literatür taramasında gebeliğinde COVID-19 geçiren anne bebekleri ile ilgili yeterli veriye rastlayamadık. Bu nedenle daha çok çalışmaya ihtiyaç vardır. Ancak çalışmamızda intrauterin kardiyak etkilenmeye rastlanmadı

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