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368 Research products, page 1 of 37

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  • Open Access English
    Authors: 
    Cohen, Alexander A.; van Doremalen, Neeltje; Greaney, Allison J.; Andersen, Hanne; Sharma, Ankur; Starr, Tyler N.; Keeffe, Jennifer R.; Fan, Chengcheng; Schulz, Jonathan E.; Gnanapragasam, Priyanthi N. P.; +12 more
    Country: United States

    To combat future SARS-CoV-2 variants and spillovers of SARS-like betacoronaviruses (sarbecoviruses) threatening global health, we designed mosaic nanoparticles presenting randomly-arranged sarbecovirus spike receptor-binding domains (RBDs) to elicit antibodies against c...

  • Open Access English
    Authors: 
    Winnett, Alexander Viloria; Porter, Michael K.; Romano, Anna E.; Savela, Emily S.; Akana, Reid; Shelby, Natasha; Reyes, Jessica A.; Schlenker, Noah W.; Cooper, Matthew M.; Carter, Alyssa M.; +6 more
    Country: United States

    Background. The analytical sensitivities of SARS-CoV-2 diagnostic tests span 6 orders of magnitude. Optimizing sample-collection methods to achieve the most reliable detection for a given sensitivity would increase the effectiveness of testing and minimize COVID-19 outb...

  • Open Access English
    Authors: 
    Carroll, Lorraine; Byrne, Fionnuala; Canty, Gillian; Gallagher, L. (Louise); Smith, Valerie;
    Country: Ireland

    Trinity Health and Education International Research Conference 2022 (THEConf 2022), Virtual Event, 8-10 March 2022 Background: The World Health Organisation (WHO) declared a global pandemic on the 11th of March 2020. The Irish government subsequently imposed the first n...

  • Open Access English
    Authors: 
    Nguyen, Minhphuong; Paul, Eric; Mills, Paul K.; Paul, Simon;
    Country: United States

    The probability of either testing COVID-19 positive or dying for three cohorts in Madera County, California in 2021 was compared. These cohorts included 1. those unvaccinated, 2. those vaccinated and 3. persons with a previous COVID-19 infection. The three groups were m...

  • Open Access English
    Authors: 
    Hahn, James Robert;
    Publisher: eScholarship, University of California
    Country: United States

    Currently, the entire globe is affected by the COVID-19 pandemic caused by the novel coronavirus, SARS-CoV-2(SCV2). The ability to detect, monitor and assess the spread of the virus is imperative to controlling the effects of the pandemic. In order to meet the need for ...

  • Open Access English
    Authors: 
    Garcia, Katherine Arias;
    Publisher: eScholarship, University of California
    Country: United States

    Only 5% of the graduates from medical schools identify as Latinx (AAMC, 2019). While, in the state of California, the growing Latinx and bilingual community is expected to exceed 40% of the state’s population with only 5% Latinx physicians (Martinez et al., 2019). Diver...

  • Open Access English
    Authors: 
    Hagaman, Natasha;
    Publisher: eScholarship, University of California
    Country: United States

    One of the factors which perpetuates gender inequality is the inequitable division of household labor, and particularly the division of child caretaking labor. Even when women are employed outside the home, many remain primarily responsible for household duties and chil...

  • Open Access English
    Authors: 
    Ary, Beatrice Elisabeth;
    Publisher: eScholarship, University of California
    Country: United States

    Cells have evolved proteins that detect foreign DNA, RNA, or proteins which then activate cellular pathways to combat bacterial or viral infection.1–4 Apolipoprotein B editing complex 3 (APOBEC3 or A3) is a host cytidine deaminase that deaminates cytidine to uridine in ...

  • Open Access English
    Authors: 
    Allen, A'Lester;
    Publisher: eScholarship, University of California
    Country: United States

    Because of the high sensitivity, molecular specificity, and non-invasive sampling technique, surface enhanced Raman scattering (SERS) is one of the most powerful analytical techniques. Additionally, its low interference from water makes SERS uniquely effective for biolo...

  • Other research product . 2022
    Open Access English
    Authors: 
    Sheng, Yanying;
    Publisher: eScholarship, University of California
    Country: United States

    This dissertation contains three essays studying topics in applied microeconomics. The first chapter studies the formation and the spread of crisis-driven racial animus during the coronavirus pandemic. Exploiting plausibly exogenous variation in the timing of the first ...