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7 research outcomes, page 1 of 1
  • publication . Preprint . Article . 2019
    Open Access
    Authors:
    Alessia Landi; Muriel Mari; Tobias Wolf; Svenja Kleiser; Christine Gretzmeier; Isabel Wilhelm; Dimitra Kiritsi; Roland Thuenauer; Roger Geiger; Alexander Nyström; ...
    Publisher: Cold Spring Harbor Laboratory
    Country: Netherlands
    Project: NWO | A three-dimensional look ... (2300175771), EC | DRIVE (765912), EC | LEC&LIP2INVADE (282105), EC | PRONKJEWAIL (713660)

    Lectins are glycan-binding proteins with no catalytic activity and ubiquitously expressed in nature. Numerous bacteria use lectins to efficiently bind to epithelia, thus facilitating tissue colonisation. Wounded skin is one of the preferred niches for Pseudomonas aerugi...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Xingdong Zhou; Yingying Cong; Tineke Veenendaal; Judith Klumperman; Dongfang Shi; Muriel Mari; Fulvio Reggiori;
    Country: Netherlands
    Project: EC | PRONKJEWAIL (713660), NWO | A three-dimensional look ... (2300175771)

    The porcine epidemic diarrhea virus (PEDV) is a coronavirus (CoV) belonging to the alpha-CoV genus and it causes high mortality in infected sucking piglets, resulting in substantial losses in the farming industry. CoV trigger a drastic reorganization of host cell membra...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Cong, Yingying; Kriegenburg, Franziska; de Haan, Cornelis A M; Reggiori, Fulvio; dI&I I&I-1;
    Country: Netherlands
    Project: NWO | The role of autophagy in ... (2300175628), NWO | A three-dimensional look ... (2300175771)

    Abstract Coronaviruses (CoV) are enveloped viruses and rely on their nucleocapsid N protein to incorporate the positive-stranded genomic RNA into the virions. CoV N proteins form oligomers but the mechanism and relevance underlying their multimerization remain to be ful...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Yingying Cong; Pauline Verlhac; Fulvio Reggiori;
    Publisher: MDPI AG
    Country: Netherlands
    Project: NWO | A three-dimensional look ... (2300175771), EC | PRONKJEWAIL (713660), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421)

    Autophagy is a conserved intracellular catabolic pathway that allows cells to maintain homeostasis through the degradation of deleterious components via specialized double-membrane vesicles called autophagosomes. During the past decades, it has been revealed that numero...

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  • other research product . Other ORP type . 2017
    Open Access English
    Authors:
    Cong, Yingying; Verlhac, Pauline; Reggiori, Fulvio;
    Project: SNSF | ER-phagy mechanisms to ma... (CRSII3_154421), EC | PRONKJEWAIL (713660), NWO | A three-dimensional look ... (2300175771)

    Autophagy is a conserved intracellular catabolic pathway that allows cells to maintain homeostasis through the degradation of deleterious components via specialized double-membrane vesicles called autophagosomes. During the past decades, it has been revealed that numero...

  • publication . Article . 2016
    Open Access English
    Authors:
    Mario Mauthe; Fulvio Reggiori;
    Publisher: Shared Science Publishers OG
    Country: Netherlands
    Project: NWO | A three-dimensional look ... (2300175771), NWO | The role of autophagy in ... (2300175628)

    The study of microbe infections has always been a very effective approach to unveil and dissect cellular pathways. Autophagy is not an exception. Although some of the breakthrough discoveries in the field were obtained using yeast, pathogens have been and still are a gr...

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  • publication . Article . 2016
    Open Access English
    Authors:
    Mario Mauthe; Martijn A. Langereis; Jennifer Jung; Xingdong Zhou; Alex Jones; Wienand A. Omta; Sharon A. Tooze; Bjoern Stork; Søren R. Paludan; Tero Ahola; ...
    Country: Netherlands
    Project: NWO | Viral strategies to evade... (2300180032), AKA | Mechanisms in the formati... (265997), NWO | A three-dimensional look ... (2300175771), NWO | The role of autophagy in ... (2300175628), WT , SNSF | ER-phagy mechanisms to ma... (CRSII3_154421), EC | XABA (282333)

    Autophagy is a catabolic process regulated by the orchestrated action of the autophagy-related (ATG) proteins. Recent work indicates that some of the ATG proteins also have autophagy-independent roles. Using an unbiased siRNA screen approach, we explored the extent of t...

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7 research outcomes, page 1 of 1